Pathophysiology of Pneumonia

Download as docx, pdf, or txt
Download as docx, pdf, or txt
You are on page 1of 1

PATHOPHYSIOLOGY OF PNEUMONIA

Contributing/Precipitating
PREDISPOSING Factors Factors
85 y.o, male Bacteria

Entry of microorganisms to respiratory system


through inspiration/aspiration (staphylococcus
and Gram-negative bacilli)

Activation of normal pulmonary defenses

Ineffective immune response resulting to


overwhelming infection

Penetrate the sterile lower respiratory tract

Organism multiplies and releases damaging toxins

Release of inflammatory mediators (IL-1,


IL-6, TNF, GCSF)

Inflammation Increased mucus Chills & fever


Airway constriction
production

Vasodilation & Hyperventilation


increase blood flow Cough
se RR

crackles Alveolar capillary


Decreased
leakage
lung
compliance
Results in:
* se BS Inflamed & fluid- DYSPNEA
* tactile filled alveolar sac
fremitus
*dullness
Altered gas
Hypoxemia
exchanged

You might also like