Agostino Bassi Elie Metchnikoff: Maestri-Coelia Ishiwatari

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Sericulture, the practice of breeding silkworms for production of raw silk, has been under

way for atleast 5000 years in China. Silkworm diseases have many different names
throughout the history of silk production, but modern scientists use French names: Pebrine,
Muscardine, Flacherie and Grasserie. The early history in discovery of insect pathogen of silk
worm and its effect on silk industry can be described through the research works of different
scientists throughout the 18th and 19th century.

AGOSTINO BASSI ELIE METCHNIKOFF


Agostino Bassi was an Italian entomologist. He He is a Russian imperial zoologist of Ukrainian
discovered that the muscardine disease of
Jewish origin best known for his pioneering
silkworms was caused by a very small organism
research in immunology. He and Paul Ehrlich
and a fungus that would eventually named
were jointly awarded the Nobel Prize in 1908
Beauveria bassiana in his honor. He preceded
Louis Pasteur in the discovery that in recognition of their work on immunity. He
microorganisms can be the cause of disease (the is known for his works on green mascurdine
germ theory of disease) disease of silkworms.

MAESTRI-COELIA LOUIS PASTEUR ISHIWATARI


Nucleo-polyhedralvirus(NPV) were first He is a French biologist, microbiologist and He was a Japanese biologist who was
observed in 1856 by these two Italian chemist renowned for his discoveries of investigating the cause of the Sotto disease
scientists. They were the first to establish principles of vaccination, pasteurization and (Sudden-collapse) that was killing larval
correlation between the presence of today regarded as the father of germ theory. populations of silkworms when he first
refractive crystals (viral occlusion bodies) and He has done research work on ‘Pebrine’ isolated the bacterium ‘Bacillus thuringiensis
symptoms of diseased silkworms. The disease of silkworms and developed a system (Bt) as the cause of disease in 1901. he named
disease is commonly known as ‘grasserie or the bacterium ‘sotto’ which was later ruled
to prevent this.
milky disease’. invalid.

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