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    DIPHENHYDRAMINE

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    Joevence Gazo Cuaresma
    Diphenhydramine hydrochloride (Benadryl) is ordered as a pre-medication for BT. It acts as an antihistamine and histamine H1 receptor antagonist to reduce allergic reaction symptoms. Common side effects include drowsiness, sedation, and dry mouth. Nurses should monitor the patient for side effects and educate them on proper usage and signs of serious adverse reactions to report.

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    DIPHENHYDRAMINE

    Uploaded by

    Joevence Gazo Cuaresma
    141 views4 pages
    Diphenhydramine hydrochloride (Benadryl) is ordered as a pre-medication for BT. It acts as an antihistamine and histamine H1 receptor antagonist to reduce allergic reaction symptoms. Common side effects include drowsiness, sedation, and dry mouth. Nurses should monitor the patient for side effects and educate them on proper usage and signs of serious adverse reactions to report.

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    Diphenhydramine hydrochloride (Benadryl) is ordered as a pre-medication for BT. It acts as an antihistamine and histamine H1 receptor antagonist to reduce allergic reaction symptoms. Common side effects include drowsiness, sedation, and dry mouth. Nurses should monitor the patient for side effects and educate them on proper usage and signs of serious adverse reactions to report.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    141 views4 pages

    DIPHENHYDRAMINE

    Uploaded by

    Joevence Gazo Cuaresma
    Diphenhydramine hydrochloride (Benadryl) is ordered as a pre-medication for BT. It acts as an antihistamine and histamine H1 receptor antagonist to reduce allergic reaction symptoms. Common side effects include drowsiness, sedation, and dry mouth. Nurses should monitor the patient for side effects and educate them on proper usage and signs of serious adverse reactions to report.

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    Date ordered: April 25, 2021

    Doctor’s order: Pre BT med: Diphenhydramine 50mg

    IVTT
    Generic Name: Diphenhydramine Hydrochloride
    Trade Name: Benadryl
    Classification

    Therapeutic: Antihistamines

    Pharmacologic: Histamine H1 antagonist

    Actions: Diphenhydramine acts as an inverse

    agonist at the H1 receptor, thereby

    reversing effects of histamine on

    capillaries, reducing allergic reaction

    symptoms. Lastly, diphenhydramine acts

    as an intracellular sodium channel

    blocker, resulting in local anesthetic

    properties. Has atropine-like, antipruritic,

    and sedative effects.


    Indications: Relief symptoms associated with

    perennial and seasonal allergic rhinitis;

    vasomotor rhinitis; mild, uncomplicated

    urticaria and angioedema; allergic

    reactions to blood or plasma; adjunctive

    therapy in anaphylactic reactions

    Contraindication: Contraindicated if patient is allergic to


    antihistamines, third trimester of

    pregnancy and if patient is lactating.

    Interactions: Drug-drug: Possible increased and

    prolonged anticholinergic effects with

    MAOIs. Risk for increased sedation with

    alcohol, CNS depressants; avoid this

    combination.

    Drug-food: Increased risk of

    hepatotoxicity with alcohol.

    Adverse Effects: CNS: Drowsiness, sedation, dizziness,

    disturbed coordination, fatigue, confusion,

    restlessness, excitation, nervousness,

    tremor, headache, blurred vision, diplopia

    CV: Hypotension, palpitations,

    bradycardia, tachycardia, extrasystoles

    GI: Epigastric distress, anorexia,

    increased appetite and weight gain,

    nausea, vomiting, diarrhea or constipation


    GU: Urinary frequency, dysuria, urinary

    retention, early menses, decreased libido,

    impotence

    Hematologic: Hemolytic anemia,

    hypoplastic anemia, thrombocytopenia,

    leukopenia, agranulocytosis,

    pancytopenia

    Respiratory: Thickening of the bronchial

    secretions, chest tightness, wheezing,

    nasal stuffiness, dry mouth, dry nose, dry

    throat, sore throat

    Other: Urticaria, rash, anaphylactic shock,

    photosensitivity, excessive perspiration


    Nursing Responsibilities: -monitor patient response, and arrange

    for adjustment of dosage to lowest

    possible effective dose

    -give with food if GI upset occurs

    -instruct to avoid alcohol to avoid serious

    sedation

    -educate patient on its common and


    serious side effects and instruct to report

    to the NOD

    -instruct patient to report if there is DOB,

    hallucinations, tremors, loss of

    coordination, bleeding or bruising, visual

    disturbances and cardiac arrhythmias.


    Rationale: Used to temporarily relieve symptoms

    due to hay fever, upper respiratory

    allergies, or the common cold, such as

    runny nose and sneezing.

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