Grade 10 - About Mendelian Genetics

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Mendelian Genetics

Introduction to Genetics
 GENETICS = branch of biology that deals with heredity
and variation of organisms.

 Chromosomes carry the hereditary information of genes


 Chromosomes (and genes) occur in pairs
Homologous Chromosomes
 New combinations of genes occur in sexual reproduction
 Fertilization from two parents
Gregor Johann Mendel
 Austrian Monk, born in what is now Czech
Republic in 1822
 Went to the university of Vienna, where he
studied botany and learned the Scientific
Method
 Mendel looked at 7 traits of pea plants:
 In 1866 he published Experiments in Plant
Hybridization, in which he established his three
Principles of Inheritance:
1) Genes exist
2) Genes occur in pairs
3) One gene of each pair is
present in the gametes
 Unfortunately his work was
largely ignored for
34 years, until 1900, when
3 independent botanists
rediscovered it.
Genetics terms you
need to know:
 Gene – a unit of heredity;
a section of DNA sequence
encoding a single protein
 Genome – the entire set
of genes in an organism

 Alleles – two genes that occupy the same position on


homologous chromosomes and that cover the same
trait (like ‘flavors’ of a trait).
 Homozygous – having identical genes for a
particular characteristic (Ex: tt, or TT)
 Heterozygous – having two different genes for
a particular characteristic (Ex: Tt)

 Dominant – the allele of a gene that masks or


suppresses the expression of an alternate
allele; indicated by a capital letter (Ex: T)
 Recessive – an allele that is masked by a
dominant allele; indicated by a lower case
letter (Ex: t).
 Genotype – the genetic makeup of an
organisms
 Phenotype – the physical appearance
of an organism (Genotype + environment)

 Monohybrid cross: a genetic cross involving a


single pair of genes (one trait)
Punnett square
 A useful tool to do genetic crosses
 For a monohybrid cross, you need a square
divided by four (looks like a window pane)

We use the
Punnett square
to predict the
genotypes and
phenotypes of
the offspring.
Using a Punnett Square
STEPS:
1. determine the genotypes of the parent organisms
2. write down your "cross" (mating)
3. draw a p-square

Parent genotypes:
TT and t t

Cross
TT  tt
Punnett square
4. "split" the letters of the genotype for each parent
& put them "outside" the p-square
5. determine the possible genotypes of the
offspring by filling in the p-square
6. summarize results (genotypes & phenotypes of
offspring)
T T
TT  tt
t Tt Tt
Genotypes:
100% T t

Phenotypes:
t Tt Tt 100% Tall plants
Punnett Square Example:
Flower color:
P = purple (dominant)

p = white (recessive)

If you cross a homozygous purple with a


heterozygous white what will the possible resulting
genotype and phenotypes be?

P P
PP x Pp
Genotype: 50% PP, 50% Pp
P PP PP
Phenotype: 100% purple
p Pp Pp
Incomplete Dominance
Genes show incomplete dominance
when the heterozygous phenotype
is intermediate.

For example: Snapdragon flowers come in many


colors.

If you cross a red snapdragon (RR) RR  rr


with a white snapdragon (rr)

You get PINK flowers (Rr)!


Rr
Incomplete dominance
When the first generation (all pink flowers) is self
pollinated, the second generation has a 1:2:1
red, pink, white ratio.
Incomplete Dominance

R r
R R R Rr

r Rr rr
Make sure to summarize what you
learned at the end of the notes.

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