Version: 2.

1
Revision Date: 07-28-2020

SAFETY DATA SHEET

According to US Regulation 29 CFR 1910.1200 (HazCom 2012)

1. Identification

Product identifier: Ammonium Chloride

Other means of identification

Product No.: 0660, 3364, 3384

Recommended restrictions
Recommended use: For Laboratory, Research or Manufacturing Use.
Restrictions on use: Not determined.

Details of the supplier of the safety data sheet

Company Name: Avantor Performance Materials, LLC

Address: 100 Matsonford Rd, Suite 200
Radnor, PA 19087

Telephone: Customer Service: 855-282-6867

Contact Person: Product Information Compliance

E-mail: info@avantormaterials.com

Emergency telephone number:

CHEMTREC: 1-800-424-9300 within US and Canada (24 hrs/day, 7 days/week)

2. Hazard(s) identification

Hazard Classification
Health Hazards
Acute toxicity (Oral) Category 4
Skin Corrosion/Irritation Category 2
Serious Eye Damage/Eye Irritation Category 2A

Unknown toxicity - Health

Acute toxicity, inhalation, dust 100 %
or mist

Label Elements

Hazard Symbol:

Signal Word: Warning

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Hazard Statement: Harmful if swallowed.

Causes serious eye irritation.

Precautionary
Statements

Prevention: Wash thoroughly after handling. Do not eat, drink or smoke when using this
product. Wear protective gloves/protective clothing/eye protection/face
protection.

Response: IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. If eye irritation
persists: Get medical advice/attention. IF SWALLOWED: Call a POISON
CENTER/doctor if you feel unwell. Rinse mouth.

Disposal: Dispose of contents/container to an appropriate treatment and disposal

facility in accordance with applicable laws and regulations, and product
characteristics at time of disposal.

Hazard(s) not otherwise None.

classified (HNOC):

3. Composition/information on ingredients

Substances

Chemical Identity CAS number Content in percent (%)*

Ammonium chloride 12125-02-9 99.5 - 100.0%

* All concentrations are percent by weight unless ingredient is a gas. Gas concentrations are in percent by volume.

4. First-aid measures

General information: Get medical advice/attention if you feel unwell. Show this safety data sheet
to the doctor in attendance.

Ingestion: Rinse mouth. Get medical attention if symptoms occur.

Inhalation: Move to fresh air. Get medical attention if symptoms persist.

Skin Contact: Wash skin thoroughly with soap and water. Get medical attention if irritation
persists after washing.

Eye contact: Immediately flush with plenty of water for at least 15 minutes. If easy to do,
remove contact lenses. Get medical attention if symptoms persist.

Most important symptoms/effects, acute and delayed

Symptoms: Harmful if swallowed. Causes serious eye irritation.

Hazards: None known.

Indication of immediate medical attention and special treatment needed

Treatment: Treat symptomatically. Symptoms may be delayed.

5. Fire-fighting measures

General Fire Hazards: In case of fire and/or explosion do not breathe fumes.
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Suitable (and unsuitable) extinguishing media

Suitable extinguishing Use fire-extinguishing media appropriate for surrounding materials.

media:

Unsuitable extinguishing None known.

media:

Specific hazards arising from Fire may produce irritating, corrosive and/or toxic gases.
the chemical:

Special protective equipment and precautions for firefighters

Special fire fighting Move containers from fire area if you can do so without risk. Use water
procedures: spray to keep fire-exposed containers cool. Cool containers exposed to
flames with water until well after the fire is out.

Special protective equipment Firefighters must use standard protective equipment including flame
for fire-fighters: retardant coat, helmet with face shield, gloves, rubber boots, and in
enclosed spaces, SCBA.

6. Accidental release measures

Personal precautions, Keep unauthorized personnel away. Keep upwind. Ventilate closed spaces
protective equipment and before entering them. Avoid inhalation of dust. Do not touch damaged
emergency procedures: containers or spilled material unless wearing appropriate protective
clothing.

Methods and material for Sweep up and place in a clearly labeled container for chemical waste.
containment and cleaning Clean surface thoroughly to remove residual contamination.
up:

Notification Procedures: Inform authorities if large amounts are involved. Prevent entry into
waterways, sewer, basements or confined areas.

Environmental Precautions: Prevent further leakage or spillage if safe to do so. Avoid discharge into
drains, water courses or onto the ground.

7. Handling and storage

Precautions for safe handling: Avoid contact with eyes, skin, and clothing. Avoid inhalation of dust. Do not
taste or swallow. Do not eat, drink or smoke when using the product. Use
only with adequate ventilation. Wash thoroughly after handling. See Section
8 of the SDS for Personal Protective Equipment.

Conditions for safe storage, Keep container tightly closed. Store in a well-ventilated place.
including any
incompatibilities:

8. Exposure controls/personal protection

Control Parameters
Occupational Exposure Limits
Chemical Identity Type Exposure Limit Values Source

Ammonium chloride - Fume. TWA 10 mg/m3 US. ACGIH Threshold Limit Values (2011)
STEL 20 mg/m3 US. ACGIH Threshold Limit Values (2011)
REL 10 mg/m3 US. NIOSH: Pocket Guide to Chemical
Hazards (2010)
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STEL 20 mg/m3 US. NIOSH: Pocket Guide to Chemical

Hazards (2010)
STEL 20 mg/m3 US. OSHA Table Z-1-A (29 CFR 1910.1000)
(1989)
TWA 10 mg/m3 US. OSHA Table Z-1-A (29 CFR 1910.1000)
(1989)
TWA 10 mg/m3 US. Tennessee. OELs. Occupational Exposure
Limits, Table Z1A (06 2008)
STEL 20 mg/m3 US. Tennessee. OELs. Occupational Exposure
Limits, Table Z1A (01 2019)
TWA PEL 10 mg/m3 US. California Code of Regulations, Title 8,
Section 5155. Airborne Contaminants (08
2010)
STEL 20 mg/m3 US. California Code of Regulations, Title 8,
Section 5155. Airborne Contaminants (08
2010)
Ammonium chloride - Total TWA 50 millions of US. OSHA Table Z-3 (29 CFR 1910.1000) (03
dust. particles per 2016)
cubic foot of
air
Ammonium chloride - TWA 15 millions of US. OSHA Table Z-3 (29 CFR 1910.1000) (03
Respirable fraction. particles per 2016)
cubic foot of
air
TWA 5 mg/m3 US. OSHA Table Z-3 (29 CFR 1910.1000) (03
2016)
Ammonium chloride - Total TWA 15 mg/m3 US. OSHA Table Z-3 (29 CFR 1910.1000) (03
dust. 2016)

Appropriate Engineering No data available.

Controls

Individual protection measures, such as personal protective equipment

General information: Good general ventilation (typically 10 air changes per hour) should be used.
Ventilation rates should be matched to conditions. If applicable, use
process enclosures, local exhaust ventilation, or other engineering controls
to maintain airborne levels below recommended exposure limits. If
exposure limits have not been established, maintain airborne levels to an
acceptable level. An eye wash and safety shower must be available in the
immediate work area.

Eye/face protection: Use tight fitting goggles if dust is generated.

Skin Protection
Hand Protection: Use suitable protective gloves if risk of skin contact.

Other: Wear suitable protective clothing.

Respiratory Protection: If engineering controls do not maintain airborne concentrations below

recommended exposure limits (where applicable) or to an acceptable level
(in countries where exposure limits have not been established), an
approved respirator must be worn. Air-purifying respirator with a high
efficiency particulate filter.

Hygiene measures: Provide eyewash station and safety shower. Always observe good personal
hygiene measures, such as washing after handling the material and before
eating, drinking, and/or smoking. Routinely wash work clothing and
protective equipment to remove contaminants.

9. Physical and chemical properties

Appearance
Physical state: Solid
Form: Granular powder
Color: White
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Odor: Odorless
Odor threshold: No data available.
pH: 4.5 - 6.0 (25 °C) (5% aqueous solution)
Melting point/freezing point: 337.8 - 341 °C
Initial boiling point and boiling range: 520 °C
Flash Point: Not applicable
Evaporation rate: No data available.
Flammability (solid, gas): Noncombustible Solid
Upper/lower limit on flammability or explosive limits
Flammability limit - upper (%): No data available.
Flammability limit - lower (%): No data available.
Explosive limit - upper (%): No data available.
Explosive limit - lower (%): No data available.
Vapor pressure: 0.133 kPa (160.4 °C)
Vapor density: No data available.
Density: 1.53 g/cm3 (20 °C)
Relative density: 1.53 (25 °C)
Solubility(ies)
Solubility in water: 372 g/l (20 °C)
758 g/l (100 °C)
Solubility (other): acetone: Practically insoluble
ether: Practically insoluble
ethyl acetate: Practically insoluble
methanol: Soluble
Partition coefficient (n-octanol/water): No data available.
Auto-ignition temperature: > 400 °C
Decomposition temperature: 338 °C
Viscosity: No data available.

Other information
Molecular weight: 53.5 g/mol (NH4Cl)

10. Stability and reactivity

Reactivity: No dangerous reaction known under conditions of normal use.

Chemical Stability: Material is stable under normal conditions.

Possibility of hazardous Hazardous polymerization does not occur.

reactions:

Conditions to avoid: Excessive heat. Moisture.

Incompatible Materials: Strong oxidizing agents. Strong acids. Nitrates. Potassium. Copper.
Halogens.

Hazardous Decomposition Ammonia. Nitrogen oxides. Hydrogen chloride.

Products:

11. Toxicological information

Information on likely routes of exposure

Inhalation: May cause irritation to the respiratory system.

Skin Contact: Causes skin irritation.

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Eye contact: Causes serious eye irritation.

Ingestion: Harmful if swallowed.

Information on toxicological effects

Acute toxicity (list all possible routes of exposure)

Oral
Product: LD 50 (Rat): 1,410 - 1,650 mg/kg

Dermal
Product: LD 50 (Rat) > 2,000 mg/kg

Inhalation
Product: No data available.

Repeated dose toxicity

Product: No data available.

Skin Corrosion/Irritation
Product: Causes skin irritation.

Serious Eye Damage/Eye Irritation

Product: Causes serious eye irritation.

Respiratory or Skin Sensitization

Product: Not a skin nor a respiratory sensitizer.

Carcinogenicity
Product: This substance has no evidence of carcinogenic properties.

IARC Monographs on the Evaluation of Carcinogenic Risks to Humans:

No carcinogenic components identified

US. National Toxicology Program (NTP) Report on Carcinogens:

No carcinogenic components identified

US. OSHA Specifically Regulated Substances (29 CFR 1910.1001-1050):

No carcinogenic components identified

Germ Cell Mutagenicity

In vitro
Product: No mutagenic components identified

In vivo
Product: No mutagenic components identified

Reproductive toxicity
Product: No components toxic to reproduction

Specific Target Organ Toxicity - Single Exposure

Product: None known.

Specific Target Organ Toxicity - Repeated Exposure

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Product: None known.

Aspiration Hazard
Product: Not classified

Other effects: None known.

12. Ecological information

Ecotoxicity:

Acute hazards to the aquatic environment:

Fish
Product: No data available.

Aquatic Invertebrates
Product: No data available.

Chronic hazards to the aquatic environment:

Fish
Product: No data available.

Aquatic Invertebrates
Product: No data available.

Toxicity to Aquatic Plants

Product: No data available.

Persistence and Degradability

Biodegradation
Product: Expected to be readily biodegradable.

BOD/COD Ratio
Product: No data available.

Bioaccumulative potential
Bioconcentration Factor (BCF)
Product: No data available on bioaccumulation.

Partition Coefficient n-octanol / water (log Kow)

Product: No data available.

Mobility in soil: No data available.

Other adverse effects: The product components are not classified as environmentally hazardous.
However, this does not exclude the possibility that large or frequent spills
can have a harmful or damaging effect on the environment.

13. Disposal considerations

Disposal instructions: Discharge, treatment, or disposal may be subject to national, state, or local
laws.
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Contaminated Packaging: Since emptied containers retain product residue, follow label warnings even
after container is emptied.

14. Transport information

DOT
Not regulated.

IMDG
Not regulated.

IATA
Not regulated.

15. Regulatory information

US Federal Regulations
TSCA Section 12(b) Export Notification (40 CFR 707, Subpt. D)
None present or none present in regulated quantities.

US. OSHA Specifically Regulated Substances (29 CFR 1910.1001-1050)

None present or none present in regulated quantities.

CERCLA Hazardous Substance List (40 CFR 302.4):

Chemical Identity Reportable quantity
Ammonium chloride 5000 lbs.

Superfund Amendments and Reauthorization Act of 1986 (SARA)

Hazard categories
Acute toxicity (any route of exposure)
Skin Corrosion or Irritation
Serious eye damage or eye irritation

SARA 302 Extremely Hazardous Substance

None present or none present in regulated quantities.

SARA 304 Emergency Release Notification

None present or none present in regulated quantities.

SARA 311/312 Hazardous Chemical

Chemical Identity Threshold Planning Quantity
Ammonium chloride 10000 lbs.

SARA 313 (TRI Reporting)

Reporting Reporting threshold for
threshold for manufacturing and
Chemical Identity other users processing
Ammonium chloride 10000 lbs. 25000 lbs.

Clean Air Act (CAA) Section 112(r) Accidental Release Prevention (40 CFR 68.130):
None present or none present in regulated quantities.

Clean Water Act Section 311 Hazardous Substances (40 CFR 117.3):
Chemical Identity Reportable quantity
Ammonium chloride Reportable quantity: 5000 lbs.

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US State Regulations

US. California Proposition 65

No ingredient requiring a warning under CA Prop 65.

US. New Jersey Worker and Community Right-to-Know Act

Chemical Identity
Ammonium chloride

US. Massachusetts RTK - Substance List

Chemical Identity
Ammonium chloride

US. Pennsylvania RTK - Hazardous Substances

Chemical Identity
Ammonium chloride

US. Rhode Island RTK

Chemical Identity
Ammonium chloride

International regulations

Montreal protocol
Not applicable

Stockholm convention
Not applicable

Rotterdam convention
Not applicable

Kyoto protocol
Not applicable

Inventory Status:
Australia AICS: On or in compliance with the inventory
Canada DSL Inventory List: On or in compliance with the inventory
China Inv. Existing Chemical Substances: On or in compliance with the inventory
Japan (ENCS) List: On or in compliance with the inventory
Japan ISHL Listing: On or in compliance with the inventory
Korea Existing Chemicals Inv. (KECI): On or in compliance with the inventory
Mexico INSQ: On or in compliance with the inventory
New Zealand Inventory of Chemicals: On or in compliance with the inventory
Philippines PICCS: On or in compliance with the inventory
Taiwan Chemical Substance Inventory: On or in compliance with the inventory
US TSCA Inventory: On or in compliance with the inventory
EINECS, ELINCS or NLP: On or in compliance with the inventory

16.Other information, including date of preparation or last revision

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NFPA Hazard ID

0 Flammability
Health
2 0
Reactivity
Special hazard.

Hazard rating: 0 - Minimal; 1 - Slight; 2 - Moderate; 3 - Serious; 4 - Severe; RNP - Rating not possible

Issue Date: 07-28-2020

Revision Information: Not relevant.

Version #: 2.1

Source of information: Sources of information used in preparing this SDS included one or more of
the following: results from in house or supplier toxicology studies, information
from the Toxicology Data Network (TOXNET), European Chemical Agency
(ECHA) substance dossiers, IARC Monographs, US National Toxicology
Program data, the Agency for Toxic Substances and Disease Registry, other
manufacturer’s SDSs and other sources, as appropriate.

Further Information: No data available.

Disclaimer: The information provided in this Safety Data Sheet (SDS) was prepared
based on data believed to be accurate as of the date of this SDS. TO THE
GREATEST EXTENT PERMITTED BY LAW, AVANTOR PERFORMANCE
MATERIALS (“AVANTOR”) EXPRESSLY DISCLAIMS ANY AND ALL
REPRESENTATIONS AND WARRANTIES REGARDING THE
INFORMATION CONTAINED HEREIN INCLUDING, WITHOUT
LIMITATION, AS TO ACCURACY, COMPLETENESS, FITNESS FOR
PURPOSE OR USE, MERCHANTABILITY, NON-INFRINGEMENT,
PERFORMANCE, SAFETY, SUITABILITY AND STABILITY. This SDS is
intended as a guide to the appropriate use, handling, storage and disposal of
the product to which it relates by properly trained personnel, and is not
intended to be comprehensive. Users of Avantor’s products are advised to
perform their own tests and to exercise their own judgment to determine the
safety, suitability and appropriate use, handling, storage and disposal of each
product and product combination for their own purposes and uses. TO THE
GREATEST EXTENT PERMITTED BY LAW, AVANTOR DISCLAIMS
LIABILITY FOR, AND BY USING AVANTOR’S PRODUCTS PURCHASER
AGREES THAT UNDER NO CIRCUMSTANCES SHALL AVANTOR BE
LIABLE FOR, SPECIAL, INDIRECT, INCIDENTAL , PUNITIVE OR
CONSEQUENTIAL DAMAGES OF ANY TYPE OR KIND, INCLUDING
WITHOUT LIMITATION, FOR LOSS OF PROFITS, REPUTATIONAL
DAMAGE, PRODUCT RECALL OR BUSINESS INTERRUPTION.

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