Product Name: Azadirachtin 10% Granular Insecticide

Page: 1 of 6
This version issued: March, 2016

Section 1 - Identification of the Material and Supplier

Chemical nature: Azadirachtin in a suitable carrier; presented as a granular product.
Trade Name: Azadirachtin 10% Granular Insecticide
APVMA Code: 49666
Product Use: Agricultural insecticide for use as described on the product label.
Supplier: Amgrow Pty Ltd
3/29 Birnie Ave
Lidcombe NSW 2141
Phone: 02 9395 1200 (office hours)
Fax: 02 9395 1241
www.amgrow.com.au
Creation Date: February, 2016
This version issued: March, 2016 and is valid for 5 years from this date.
Poisons Information Centre: Phone 13 1126 from anywhere in Australia

Section 2 - Hazards Identification

Statement of Hazardous Nature
This product is classified as: Xn, Harmful. N, Dangerous to the environment. Hazardous according to the criteria of
SWA.
Not a Dangerous Good according to Australian Dangerous Goods (ADG) Code, IATA or IMDG/IMSBC criteria.
SUSMP Classification: S5
ADG Classification: None allocated. Not a Dangerous Good according to Australian Dangerous Goods (ADG)
Code, IATA or IMDG/IMSBC criteria.
UN Number: None allocated

GHS Signal word: WARNING

Acute Toxicity Oral Category 4
Hazardous to aquatic environment Short term/Chronic Category 2
HAZARD STATEMENT:
H302: Harmful if swallowed.
H411: Toxic to aquatic life with long lasting effects.
PREVENTION
P102: Keep out of reach of children.
P262: Do not get in eyes, on skin, or on clothing.
P264: Wash contacted areas thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P273: Avoid release to the environment.
P280: Wear protective gloves, protective clothing and eye or face protection.
RESPONSE
P352: Wash with plenty of soap and water.
P301+P312: IF SWALLOWED: Call a POISON CENTRE or doctor if you feel unwell.
P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P391: Collect spillage.
P370+P378: Not combustible. Use extinguishing media suited to burning materials.
STORAGE
P410: Protect from sunlight.
P402+P404: Store in a dry place. Store in a closed container.
P403+P235: Store in a well-ventilated place. Keep cool.

SAFETY DATA SHEET

Issued by: Amgrow Pty Ltd Phone: 02 9395 1200 (office hours)
Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)
 Product Name: Azadirachtin 10% Granular Insecticide
Page: 2 of 6
This version issued: March, 2016

DISPOSAL
P501: Dispose of contents and containers as specified on the registered label.
Emergency Overview
Physical Description & Colour: coloured granules.
Odour: No data re odour.
Major Health Hazards: Azadirachtin is harmful to humans. Symptoms of acute exposure to organophosphate or
cholinesterase-inhibiting compounds may include the following: numbness, tingling sensations, incoordination,
headache, dizziness, tremor, nausea, abdominal cramps, sweating, blurred vision, difficulty breathing or respiratory
depression, and slow heartbeat. Very high doses may result in unconsciousness, incontinence, and convulsions or
fatality. harmful if swallowed. Signs and symptoms associated with mild exposures to organophosphate and
carbamate pesticides include: headache, fatigue, dizziness, loss of appetite with nausea, stomach cramps and
diarrhoea; blurred vision associated with excessive tearing; contracted pupils of the eye; excessive sweating and
salivation; slowed heartbeat, often fewer than 50 per minute; rippling of surface muscles just under the skin. These
symptoms may be mistaken for those of flu, heat stroke or heat exhaustion, or upset stomach. Moderately severe
organophosphate and carbamate insecticide poisoning cases exhibit all the signs and symptoms found in mild
poisonings, but in addition, the victim: is unable to walk; often complains of chest discomfort and tightness; exhibits
marked constriction of the pupils (pinpoint pupils); exhibits muscle twitching; has involuntary urination and bowel
movement. Severe poisonings are indicated by incontinence, unconsciousness and seizures.

Section 3 - Composition/Information on Ingredients

Ingredients CAS No Conc,%
Azadirachtin 11141-17-6 10
Silicon Dioxide 14808-60-7 65
Lignin sulfonate 8061-51-6 25
This is a commercial product whose exact ratio of components may vary slightly. Minor quantities of other non
hazardous ingredients are also possible.
The SWA TWA exposure value is the average airborne concentration of a particular substance when calculated over a normal 8 hour working day
for a 5 day working week. The STEL (Short Term Exposure Limit) is an exposure value that may be equalled (but should not be exceeded) for no
longer than 15 minutes and should not be repeated more than 4 times per day. There should be at least 60 minutes between successive exposures
at the STEL. The term "peak "is used when the TWA limit, because of the rapid action of the substance, should never be exceeded, even briefly.

Section 4 - First Aid Measures

General Information:
You should call The Poisons Information Centre if you feel that you may have been poisoned, burned or irritated by
this product. The number is 13 1126 from anywhere in Australia (0800 764 766 in New Zealand) and is available at all
times. Have this SDS with you when you call.
If swallowed, splashed on skin or inhaled, contact a Poisons Information Centre or a doctor at once. Remove any
contaminated clothing and wash skin thoroughly. Hospital treatment may be necessary.
Inhalation: First aid is not generally required. If in doubt, contact a Poisons Information Centre or a doctor.
Skin Contact: Gently brush away excess particles. Wash gently and thoroughly with water (use non-abrasive soap if
necessary) for 5 minutes or until chemical is removed.
Eye Contact: Quickly and gently brush particles from eyes. No effects expected. If irritation does occur, flush
contaminated eye(s) with lukewarm, gently flowing water for 5 minutes or until the product is removed. Obtain medical
advice if irritation becomes painful or lasts more than a few minutes. Take special care if exposed person is wearing contact
lenses.
Ingestion: If swallowed, do NOT induce vomiting. Wash mouth with water and contact a Poisons Information
Centre, or call a doctor.

Section 5 - Fire Fighting Measures

Fire and Explosion Hazards: The major hazard in fires is usually inhalation of heated and toxic or oxygen
deficient (or both), fire gases. There is no risk of an explosion from this product under normal circumstances if it is
involved in a fire.
Only small quantities of decomposition products are expected from this product at temperatures normally achieved in
a fire.
Fire decomposition products from this product are likely to be irritating if inhaled.

SAFETY DATA SHEET

Issued by: Amgrow Pty Ltd Phone: 02 9395 1200 (office hours)
Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)
 Product Name: Azadirachtin 10% Granular Insecticide
Page: 3 of 6
This version issued: March, 2016

Extinguishing Media: Not combustible. Use extinguishing media suited to burning materials.
Fire Fighting: If a significant quantity of this product is involved in a fire, call the fire brigade.
Flash point: Does not burn.
Upper Flammability Limit: Does not burn.
Lower Flammability Limit: Does not burn.
Autoignition temperature: Not applicable - does not burn.
Flammability Class: Does not burn.

Section 6 - Accidental Release Measures

Accidental release: In the event of a major spill, prevent spillage from entering drains or water courses. As a minimum,
wear overalls, goggles and gloves. Suitable materials for protective clothing include rubber. Eye/face protective equipment
should comprise as a minimum, protective goggles. If there is a significant chance that dusts are likely to build up in cleanup
area, we recommend that you use a suitable dust mask.
Stop leak if safe to do so, and contain spill. Sweep up and shovel or collect recoverable product into labelled
containers for recycling or salvage, and dispose of promptly. Consider vacuuming if appropriate. Recycle containers
wherever possible after careful cleaning. Refer to product label for specific instructions. After spills, wash area
preventing runoff from entering drains. If a significant quantity of material enters drains, advise emergency services.
Full details regarding disposal of used containers, spillage and unused material may be found on the label. If there is
any conflict between this SDS and the label, instructions on the label prevail. Ensure legality of disposal by consulting
regulations prior to disposal. Thoroughly launder protective clothing before storage or re-use. Advise laundry of nature
of contamination when sending contaminated clothing to laundry.

Section 7 - Handling and Storage

Handling: Keep exposure to this product to a minimum, and minimise the quantities kept in work areas. Check Section
8 of this SDS for details of personal protective measures, and make sure that those measures are followed. The
measures detailed below under "Storage" should be followed during handling in order to minimise risks to persons using
the product in the workplace. Also, avoid contact or contamination of product with incompatible materials listed in Section
10.
Storage: This product is a Scheduled Poison. Observe all relevant regulations regarding sale, transport and storage of
this schedule of poison. Protect this product from light. Store in the closed original container in a dry, cool, well-ventilated
area out of direct sunlight. Make sure that the product does not come into contact with substances listed under
"Incompatibilities" in Section 10. Check packaging - there may be further storage instructions on the label.

Section 8 - Exposure Controls and Personal Protection

The following Australian Standards will provide general advice regarding safety clothing and equipment:

The ADI for Azadirachtin is set at 0.003mg/kg/day. The corresponding NOEL is set at 0.03mg/kg/day. ADI
means Acceptable Daily Intake; NOEL means No-observable-effect-level. Data from Australian ADI List, June
2014.
No special equipment is usually needed when occasionally handling small quantities. The following instructions are
for bulk handling or where regular exposure in an occupational setting occurs without proper containment systems.
Ventilation: This product should only be used in a well ventilated area. If natural ventilation is inadequate, use of a fan
is suggested.
Eye Protection: Eye protection such as protective glasses or goggles is recommended when this product is being
used.
Skin Protection: You should avoid contact even with mild skin irritants. Therefore you should wear suitable
impervious elbow-length gloves and facial protection when handling this product. See below for suitable material
types.
Protective Material Types: We suggest that protective clothing be made from the following materials: rubber.
Respirator: If there is a significant chance that dusts are likely to build up in the area where this product is being
used, we recommend that you use a suitable dust mask.
Safety deluge showers should, if practical, be provided near to where this product is being handled commercially.

SAFETY DATA SHEET

Issued by: Amgrow Pty Ltd Phone: 02 9395 1200 (office hours)
Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)
 Product Name: Azadirachtin 10% Granular Insecticide
Page: 4 of 6
This version issued: March, 2016

Section 9 - Physical and Chemical Properties:

Physical Description & colour: Tan coloured granules.
Odour: No data re odour.
Boiling Point: Not available.
Freezing/Melting Point: No specific data. Solid at normal temperatures.
Volatiles: No specific data. Expected to be low at 100°C.
Vapour Pressure: Negligible at normal ambient temperatures.
Vapour Density: Not applicable.
Specific Gravity: No data. Bulk density 1.1
Water Solubility: Insoluble.
pH: No data.
Volatility: Negligible at normal ambient temperatures.
Odour Threshold: No data.
Evaporation Rate: Not applicable.
Coeff Oil/water Distribution: No data
Viscosity: Not applicable.
Autoignition temp: Not applicable - does not burn.

Section 10 - Stability and Reactivity

Reactivity: This product is unlikely to react or decompose under normal storage conditions. However, if you have any
doubts, contact the supplier for advice on shelf life properties.
Conditions to Avoid: Protect this product from light. Store in the closed original container in a dry, cool, well-
ventilated area out of direct sunlight.
Incompatibilities: strong acids, strong bases, strong oxidising agents.
Fire Decomposition: Only small quantities of decomposition products are expected from this product at temperatures
normally achieved in a fire. Combustion forms carbon dioxide, and if incomplete, carbon monoxide and possibly smoke.
Water is also formed. May form nitrogen and its compounds, and under some circumstances, oxides of nitrogen.
Occasionally hydrogen cyanide gas in reducing atmospheres. May form oxides of phosphorus and other phosphorus
compounds. May form hydrogen chloride gas, other compounds of chlorine. Carbon monoxide poisoning produces
headache, weakness, nausea, dizziness, confusion, dimness of vision, disturbance of judgment, and unconsciousness
followed by coma and death.
Polymerisation: This product will not undergo polymerisation reactions.

Section 11 - Toxicological Information

Toxicity: An information profile for Azadirachtin is available at http://extoxnet.orst.edu/pips/ghindex.html
Acute toxicity: Azadirachtin is harmful to humans. Symptoms of acute exposure to organophosphate or
cholinesterase-inhibiting compounds may include the following: numbness, tingling sensations, incoordination,
headache, dizziness, tremor, nausea, abdominal cramps, sweating, blurred vision, difficulty breathing or respiratory
depression, and slow heartbeat. Very high doses may result in unconsciousness, incontinence, and convulsions or
fatality. Persons with respiratory ailments, recent exposure to cholinesterase inhibitors, cholinesterase impairment, or
liver malfunction are at increased risk from exposure to Azadirachtin. The oral LD50 for Azadirachtin in rats is 95 to 270
mg/kg. The LD 50 for Azadirachtin is 60 mg/kg in mice, 1000 mg/kg in rabbits, 32 mg/kg in chickens, 500 to 504 mg/kg
in guinea pigs, and 800 mg/kg in sheep. The dermal LD 50 is greater than 2000 mg/kg in rats, and 1000 to 2000
mg/kg in rabbits. The 4-hour inhalation LC50 for Azadirachtin in rats is greater than 0.2 mg/L.
Chronic toxicity: Repeated or prolonged exposure to organophosphates may result in the same effects as acute
exposure including the delayed symptoms. Other effects reported in workers repeatedly exposed include impaired
memory and concentration, disorientation, severe depressions, irritability, confusion, headache, speech difficulties,
delayed reaction times, nightmares, sleepwalking, and drowsiness or insomnia. Rats and mice given technical
Azadirachtin in the diet for 104 weeks showed no adverse effects other than cholinesterase inhibition. Two-year
feeding studies using doses of 1 and 3 mg/kg/day of Azadirachtin in rats showed moderate depression of
cholinesterase. Cholinesterase levels recovered when the experimental feeding was discontinued. Identical results
occurred in a 2-year feeding study with dogs. Human volunteers who ingested 0.1 mg/kg/day of Azadirachtin for 4
weeks showed significant plasma cholinesterase inhibition.
Reproductive effects: Current evidence indicates that Azadirachtin does not adversely affect reproduction.

SAFETY DATA SHEET

Issued by: Amgrow Pty Ltd Phone: 02 9395 1200 (office hours)
Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)
 Product Name: Azadirachtin 10% Granular Insecticide
Page: 5 of 6
This version issued: March, 2016

Teratogenic effects: Available evidence suggests that Azadirachtin is not teratogenic. No birth defects were seen in
the offspring of male and female rats fed 1.0 mg/kg/day during a three-generation reproduction and fertility study.
Mutagenic effects: There is no evidence that Azadirachtin is mutagenic. No evidence of mutagenicity was found in
any of four tests performed.
Carcinogenic effects: There is no evidence that Azadirachtin is carcinogenic.
Organ toxicity: Azadirachtin primarily affects the nervous system through inhibition of cholinesterase, an enzyme
required for proper nerve functioning.
Fate in humans and animals: Azadirachtin is readily absorbed into the bloodstream through the gastrointestinal tract
if it is ingested, through the lungs if it is inhaled, or through the skin if there is dermal exposure. In humans,
Azadirachtin and its principal metabolites are eliminated rapidly. There is no data to hand indicating any particular
target organs.
Classification of Hazardous Ingredients
Ingredient Risk Phrases
Azadirachtin >=10%Conc<25%: Xn; R22
• Acute toxicity - category 3
• Hazardous to the aquatic environment (acute) - category 1
• Hazardous to the aquatic environment (chronic) - category 1
Potential Health Effects
Inhalation:
Short Term Exposure: Symptoms are described fully above.
Long Term Exposure: No data for health effects associated with long term inhalation.
Skin Contact:
Short Term Exposure: Symptoms are described fully above.
Long Term Exposure: No data for health effects associated with long term skin exposure.
Eye Contact:
Short Term Exposure: This product may be irritating to eyes, but is unlikely to cause anything more than mild
transient discomfort.
Long Term Exposure: No data for health effects associated with long term eye exposure.
Ingestion:
Short Term Exposure: Symptoms are described fully above.
Long Term Exposure: No data for health effects associated with long term ingestion.
Carcinogen Status:
SWA: No significant ingredient is classified as carcinogenic by SWA.
NTP: No significant ingredient is classified as carcinogenic by NTP.
IARC: No significant ingredient is classified as carcinogenic by IARC.
Section 12 - Ecological Information
Toxic to aquatic organisms, may cause long-term adverse effects to the aquatic environment. This product is
biodegradable. It will not accumulate in the soil or water or cause long term problems.
Effects on birds: Azadirachtin is moderately to very highly toxic to birds.
Effects on aquatic organisms: Azadirachtin is very highly toxic to freshwater fish, aquatic invertebrates and
estuarine and marine organisms. Cholinesterase inhibition was observed in acute toxicity tests of fish exposed to very
low concentrations of this insecticide. Application of concentrations as low as 0.01 pounds of active ingredient per
acre may cause fish and aquatic invertebrate deaths. Due to its high acute toxicity and its persistence in sediments,
Azadirachtin may represent a hazard to sea bottom dwellers. Smaller organisms appear to be more sensitive than
larger ones.
Effects on other organisms: Aquatic and general agricultural uses of Azadirachtin pose a serious hazard to wildlife
and honeybees.
Environmental Fate:
Breakdown in soil and groundwater: Azadirachtin is moderately persistent in soils. The half-life of Azadirachtin in
soil is usually between 60 and 120 days, but can range from 2 weeks to over 1 year, depending on the soil type,
climate, and other conditions. Azadirachtin adsorbs strongly to soil particles and it is not readily soluble in water. It is
therefore immobile in soils and unlikely to leach or to contaminate groundwater. TCP, the principal metabolite of
SAFETY DATA SHEET
Issued by: Amgrow Pty Ltd Phone: 02 9395 1200 (office hours)
Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)
 Product Name: Azadirachtin 10% Granular Insecticide
Page: 6 of 6
This version issued: March, 2016

Azadirachtin, adsorbs weakly to soil particles and appears to be moderately mobile and persistent in soils.
Breakdown in water: The concentration and persistence of Azadirachtin in water will vary depending on the type of
formulation. The rate of hydrolysis is constant in acidic to neutral waters, but increases in alkaline waters. In water at
pH 7.0 and 25°C, it had a half-life of 35 to 78 days.
Breakdown in vegetation: Azadirachtin may be toxic to some plants, such as lettuce. Residues remain on plant
surfaces for approximately 10 to 14 days. Data indicate that this insecticide and its soil metabolites can accumulate in
certain crops.

Section 13 - Disposal Considerations

Disposal: Special help is available for the disposal of Agricultural Chemicals. The product label will give general advice
regarding disposal of small quantities, and how to cleanse containers. However, for help with the collection of unwanted
rural chemicals, contact ChemClear 1800 008 182 http://www.chemclear.com.au/ and for help with the disposal of empty
drums, contact DrumMuster http://www.drummuster.com.au/ where you will find contact details for your area.

Section 14 - Transport Information

UN Number: 1993
Class: 3
Package: III
Section 15 - Regulatory Information
AICS: All of the significant ingredients in this formulation are compliant with NICNAS regulations.
The following ingredient: Azadirachtin, is mentioned in the SUSMP.

Section 16 - Other Information

This SDS contains only safety-related information. For other data see product literature.
Acronyms:
ADG Code Australian Code for the Transport of Dangerous Goods by Road and Rail (7 th edition)
AICS Australian Inventory of Chemical Substances
SWA Safe Work Australia, formerly ASCC and NOHSC
CAS number Chemical Abstracts Service Registry Number
Hazchem Code Emergency action code of numbers and letters that provide information to emergency
services especially firefighters
IARC International Agency for Research on Cancer
NOS Not otherwise specified
NTP National Toxicology Program (USA)
R-Phrase Risk Phrase
SUSMP Standard for the Uniform Scheduling of Medicines & Poisons
UN Number United Nations Number
THIS SDS SUMMARISES OUR BEST KNOWLEDGE OF THE HEALTH AND SAFETY HAZARD INFORMATION OF THE PRODUCT AND HOW
TO SAFELY HANDLE AND USE THE PRODUCT IN THE WORKPLACE. EACH USER MUST REVIEW THIS SDS IN THE CONTEXT OF HOW
THE PRODUCT WILL BE HANDLED AND USED IN THE WORKPLACE.
IF CLARIFICATION OR FURTHER INFORMATION IS NEEDED TO ENSURE THAT AN APPROPRIATE RISK ASSESSMENT CAN BE MADE,
THE USER SHOULD CONTACT THIS COMPANY SO WE CAN ATTEMPT TO OBTAIN ADDITIONAL INFORMATION FROM OUR SUPPLIERS
OUR RESPONSIBILITY FOR PRODUCTS SOLD IS SUBJECT TO OUR STANDARD TERMS AND CONDITIONS, A COPY OF WHICH IS SENT
TO OUR CUSTOMERS AND IS ALSO AVAILABLE ON REQUEST.

Please read all labels carefully before using product.

SAFETY DATA SHEET

Issued by: Amgrow Pty Ltd Phone: 02 9395 1200 (office hours)
Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)