Manor Drills - Module 5

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Manor Drills - Module 5

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1. Specific quantity of drug product having the uni- B


form character and quantity, produced during a single
manufacturing process
a.Lot
b.Batch
c.Product line
d.Bulk

2. Type of parabens that disrupt the endocrine system C


a.Methyl
b.Propyl
c.Long-chain
d.Short-chain

3. Also known as compressed lozenges B


a.Candies
b.Troches
c.Pastilles
d.Lollipops

4. A type of tablet that dissolves slowly in the cheeks for C


systemic absorption
a.Chewable tablet
b.Orally disintegrating tablet
c.Buccal tablet
d.Sublingual tablet

5. Lacrimal fluid has an isotonicity values correspond- D


ing to that of NaCl solution with the strength of
a.0.1%
b.9.0%
c.1.0%
d.0.9%

6. Burrow's solution is used as C


a.Diluent
b.Douche
c.Astringent
d.Mouthwash

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7. Gas used in gas sterilization B


a.Carbon dioxide
b.Ethylene oxide
c.Butane
d.CFCs

8. Pencil-shaped suppositories C
a.Rectal suppositories
b.Vaginal suppositories
c.Urethral suppositories
d.Ocular suppositories

9. Addition of an equal volume of diluent to a potent C


substance placed in a mortar
a.Spatulation
b.Trituration
c.Geometric dilution
d.Tumbling

10. Describe the flow property of a powder based on the A


angle of repose if the height of the powder cone is 5.8
cm and the horizontal spread is 20 cm
a.Excellent
b.Good
c.Fair
d.Passable

11. Most widely used milling equipment that uses a high D


speed rotor to which swinging arms are fixed
a.Roller mill
b.Edge runner mill
c.Ball mill
d.Hammer mill

12. The following are used as disintegrants, except: A


a.Gelatin
b.Starch paste
c.Sodium starch glycolate
d.Microcrystalline cellulose

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13. Long-acting form or polymorph of insulin A


a.Crystalline
b.Amorphous
c.Alpha
d.Beta

14. The required class for compounding area in sterile D


production
a.Class 100,000
b.Class 10, 000
c.Class 1,000
d.Class 100

15. Most penetrating form of radiation C


a.Alpha radiation
b.Beta radiation
c.Gamma radiation
d.Electron radiation

16. It is the policy of the state to safeguard the integrity of A


its territory and the well-being of its citizenry particu-
larly the youth, from the harmful effects of dangerous
drugs.
a.RA 9165
b.RA 8981
c.RA 9994
d.RA 7581

17. Moisture content requirement for soft-gelatin cap- B


sules
a.
3 - 6%
b.
6 - 10%
c.
12 - 16%
d.
16 - 20%

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18. Part of the tableting machine that guides the move- D
ment of punches
a.Hopper
b.Feed shoe
c.Die
d.Cam track

19. Also known as pessaries B


a.Rectal suppositories
b.Vaginal suppositories
c.Urethral suppositories
d.Ocular suppositories

20. Formation of paste by addition of non-solvent liquid B


(Mineral oil in water-soluble substances)
a.Trituration
b.Levigation
c.Pulverization by Intervention
d.Sifting

21. First TDDS developed D


a.
Duragesic
b.
Androderm
c.
Testoderm
d.
Transderm Scop

22. Compute for the osmotic pressure in atm of a 0.884M C


of sucrose solution at 16°C
a.25.96 atm
b.25.69 atm
c.20.96 atm
d.52.96 atm

23. Cup and bob viscometer type where the bob is rotat- A
ed
a.Searle type
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b.Couette Type
c.Cone and Plate Type
d.Ostwald Type

24. Hydroalcoholic solutions prepared from vegetable A


drugs or chemical substances
a.Tinctures
b.Elixirs
c.Spirits
d.Fluid extracts

25. Which example of bulk powder is dissolved in warm A


water prior to use as cleansing agent or antiseptic for
body cavity?

I. Dentifrices
II. Dusting Powders
III. Douche Powders
IV. Insufflations
V. Triturations
a.III
b.V
c.II
d.I

26. The following are Van der Waals forces of attraction, A


except:
a.Hydrogen bonding
b.Dipole-induced dipole
c.Keesom forces
d.Debye forces

27. Part of transdermal drug delivery system (TDDS) that A


prevents water and drug loss
a.Occlusive backing film
b.Drug reservoir
c.Adhesive layer
d.Release laye

28. B
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Largest capsule size for human
a.0000
b.000
c.1
d.5

29. To promote, encourage, and require the use of gener- A


ic terminology of drugs.
a.RA 6675
b.RA 8981
c.RA 9711
d.RA 10918

30. In Stokes law, the parameter that has the greatest A


effect on the sedimentation rate is:
a.Diameter of the particle
b.Density of the particle
c.Density of the medium
d.Gravity

31. Expanded Senior Citizen Act of 2010 D


a.RA 9156
b.RA 6675
c.RA 8423
d.RA 9994

32. Hydrophilic ointment is what type of ointment base C


a.Hydrocarbon base
b.Absorption base
c.Water-removable base
d.Water-soluble base

33. This is known as heat content and it is the heat re- D


quired to increase the internal energy and to perform
work.
a.Specific heat
b.Heat potential
c.Entropy
d.Enthalpy

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34. A type of container that is impervious to air or any C
other gas
a.Well-closed
b.Tight
c.Hermetic
d.Tamper-resistant

35. Autoclave settings D


a.

121°C, 15 psi, 30 - 45 min

b.
121°C, 30 psi, 15 - 20 min
c.
100°C, 15 psi, 15 - 20 min
d.
121°C, 15 psi, 15 - 20 min

36. USP official method of particle size analysis A


a.Sieve analysis
b.Optical microscopy
c.Automatic particle counter
d.Sedimentation rate

37. The most preferred method of syrup preparation D


a.Solution with heat
b.Solution without heat
c.Reconstitution
d.Percolation

38. Treated soda-lime glass B


a.Type I
b.Type II
c.Type III
d.NP

39. Step in sugar coating that adds most weight C


a.Sealing
b.Subcoating
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c.Syruping
d.Polishing

40. FD&C Red No.40 B


a.Indigotine
b.Allura Red
c.Erythrosine
d.Tartrazine

41. What manufacturing process is applicable for Hard B


Gelatin Capsules?
a.Fusion method
b.Pin method
c.Tip Seal Method
d.Rotary Die Process

42. A sweetener that is 500x sweeter than sucrose D


a.Acesulfame potassium
b.Aspartame
c.Sucralose
d.Saccharin

43. Flavorant that mask bitter taste of drugs A


a.Chocolate
b.Orange
c.Vanilla
d.Butterscotch

44. Most inert grade of mixing tanks A


a.SS 316
b.SS 304
c.SS 136
d.SS 403

45. Most recommended rotating shell mixers that can A


alternately combine and draw apart the raw materials
a.V-shell blender
b.Sigma blade mixer
c.Double-cone blender
d.Planetary mixer
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46. Type of manufacturing activity wherein a competent D


manufacturing company manufactures products of
other company
a.Primary manufacturing
b.Secondary manufacturing
c.Tertiary manufacturing
d.Toll manufacturing

47. A type of powder paper that is transparent and wa- D


ter-proof, suitable for deliquescent and hygroscopic
drugs
a.Bond paper
b.Glassine
c.Vegetable parchment
d.Wax pape

48. FDA Act of 2009 C


a.RA 9502
b.RA 7581
c.RA 9711
d.RA 9502

49. The PRC Modernization Act of 2000 B


a.RA 10912
b.RA 8981
c.RA 8423
d.RA 9711

50. What manufacturing process is applicable for Soft B


Gelatin Capsules?
a.Tip Seal Method
b.Rotary Die Process
c.Pin method
d.Fusion Method

51. Simple ointment is a mixture of D


a.White petrolatum + white wax
b.White petrolatum + yellow wax

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c.Yellow petrolatum + white wax
d.Yellow petrolatum + yellow wax

52. Gas law wherein V and T are variable and P, n, R are B


held constant
a.
Boyle's Law
b.
Charles' Law
c.
Avogadro's Law
d.
Gay-Lussac's Law

53. An emulsion instability which defined as the irre- C


versible separation into a later due to coalescence of
the internal phase
a.Sedimentation
b.Creaming
c.Breaking or Cracking
d.Phase inversion

54. Traditional and Alternative Medicine Act of 1997 C

a.RA 9502
b.RA 8981
c.RA 8423
d.RA 10912

55. Use of Tragacanth in tablet formulation B


a.Disintegrant
b.Binder
c.Diluent
d.Lubricant

56. Which example of bulk powder is locally applied A


non-toxic powders that have no systemic action?
I. Dentifrices
II. Dusting Powders
III. Douche Powders
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IV. Insufflations
V. Triturations
a.II
b.III
c.V
d.I

57. Too much of this excipient in the formulation of effer- A


vescent granules causes a sticky product
a.Citric acid
b.Tartaric acid
c.Malic acid
d.Fumaric acid

58. Most widely used pressurizable container in aerosols C


a.Aluminum
b.Glass
c.Tin-plated steel
d.Brass

59. Range of HLB value in the Griffin scale for anti-foam- A


ing agents
a.0-3
b.3-8
c.8-16
d.16-18

60. An automatic particle counter that uses electric resis- B


tance to determine the size of the particle
a.HIAC Royco
b.Coulter counter
c.Gelman
d.Abbe

61. Type of extract where nearly all solvent is removed B


a.Semiliquid
b.Pilular
c.Powdered
d.Marc

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62. The gram-molecular volume of gas at STP is equal to: C
a.1.0 L
b.2.24 L
c.22.4 L
d.22.4 mL

63. Which example of bulk powder is blown into a body A


cavity using a special device?I. DentifricesII. Dusting
PowdersIII. Douche PowdersIV. InsufflationsV. Tritura-
tions
a.IV
b.III
c.V
d.I

64. The Avogadros number is equal to A


a.6.02 x 1023
b.1.802 x 1023
c.9.6 x 1023
d.6.0 x 1023

65. A drug is soluble if its 1 part can be dissolved to C


a.Less than 1 part of solvent
b.1 to 10 parts of solvent
c.10 to 30 parts of solvent
d.30 to 100 parts of solvent

66. The ratio of the void volume to the bulk volume of the A
packing
a.Porosity
b.Packing arrangement
c.Bulkiness
d.Flow particles

67. What manufacturing process is applicable for closing C


ampules?
a.Wet Granulation Method
b.Pin Method
c.Tip Seal Method
d.Fusion Method
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68. Type of tablet defects in which there is a partial or B


complete separation of the top or bottom crown
a.Lamination
b.Capping
c.Cracking
d.Chipping

69. In optical microscopy, this is the longest tangent line B


that can be measured in a particle
a.Martin diameter
b.Feret diameter
c.Projected area diameter
d.Longest diameter

70. Generics Act of 1988 A


a.RA 6675
b.RA 8981
c.RA 9165
d.RA 8203

71. The biological half-life of a drug that is eliminated by C


1st order is mathematically represented by:
a.1/k
b.log k
c.0.693/k
d.2.303/k

72. Composition of glycerogelatin C


a.40% gelatin, 35% glycerin, 15% water, 10% API
b.45% glycerin, 30% water, 15% gelatin, 10% API
c.40% glycerin, 35% water, 15% gelatin, 10% API
d.45% gelatin, 30% glycerin, 15% water, 10% API

73. The following are considered as true antioxidants, A


except:
a.Vitamin C
b.Vitamin E
c.BHT
d.BHA
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74. Which example of bulk powder is referred to as dilu- C


tions of potent powdered drugs?
I. Dentifrices
II. Dusting Powders
III. Douche Powders
IV. Insufflations
V. Triturations
a.IV
b.III
c.V
d.I

75. Required temperature for specific gravity determina- C


tion
a.15.56°C
b.30°C
c.25°C
d.20°C

76. The intermolecular forces exist between Cl2 and CBr4 C


are:
a.Dipole-dipole
b.Dipole-induced dipole
c.Induced dipole-induced dipole
d.Ion-induced dipole

77. Using White Vincent Method, compute for the re- B


quired volume to make 0.3 g of Atropine sulfate
(E=0.13) isotonic.
a.3.9 mL
b.4.3 mL
c.25.6 mL
d.33.3 mL

78. Which of the following is a colligative property? A


a.Osmotic Pressure
b.Boiling Point
c.Freezing Point
d.Vapor Pressure
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79. Preservative used in hard gelatin capsules C


a.Parabens
b.Benzyl benzoate
c.Sulfur dioxide
d.Titanium dioxide

80. The dissolution of drug is calculated using B


a.Henderson-Hasselbalch
b.Noyes-Whitney
c.Arhhenius
d.Stokes

81. A dispersion system that composed of small inorgan- A


ic particles and large organic molecules dispensed
throughout a liquid vehicle
a.Gel
b.Cream
c.Paste
d.Magma

82. Which manufacturing process is applicable for semi- D


solid dosage forms?
a.Rotary Die Process
b.Wet granulation
c.Tip Seal
d.Fusion Method

83. Reliable sealing method for ampule closure C


a.Tip sealing
b.Bead sealing
c.Pull sealing
d.Band sealing

84. Type A hydrolysis of gelatin A


a.Acid
b.Base
c.Salt
d.Partial

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85. Compute for the E-value of Zinc Chloride (MW=135.9) B
with an Liso of 5.1.
a.0.46
b.0.64
c.453
d.1.22

86. To have an effective competition policy in the supply B


and demand of quality drugs. .
a.RA 10918
b.RA 9502
c.RA 8423
d.RA 10912

87. Method of granulation used for moisture- and B


heat-sensitive drugs
a.Wet granulation
b.Dry granulation
c.Melt granulation
d.Direct compression

88. Storage condition: Cool C


a.
-20 to -10°C
b.
2 to 8°C
c.
8 to 15°C
d.
15 to 20°C

89. What manufacturing process is applicable for B


tablets?
a.Rotary Die Process
b.Wet Granulation
c.Tip Seal Method
d.Fusion Method

90. One of its objectives is to standardize and regulate B


the pharmacy education in the country.
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a.RA 10912
b.RA 10918
c.RA 8203
d.RA 9994

91. Crystal symmetry of Urea B


a.Cubic
b.Tetragonal
c.Hexagonal
d.Rhombic

92. Convert 37.5°C to Fahrenheit B


a.
98.6 °F
b.
99.5 °F
c.
100.4 °F
d.
100.3 °F

93. To safeguard the health of the people against coun- B


terfeit drug.
a.RA 9165
b.RA 8203
c.RA 9994
d.RA 9711

94. The buffer equation is also known as C


a.Noyes-Whitney
b.Arrhenius
c.Henderson-Hasselbalch
d.Van't hoff

95. Describe the flow characteristic based on Hausner B


ratio if the bulk volume is 70 mL and the tapped
volume is 60 mL
a.Excellent
b.Good
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c.Fair
d.Passable

96. Most stable polymorph of cocoa butter B


a.Alpha
b.Beta
c.Beta prime
d.Gamma

97. Type of plastic used in blister packs C


a.1
b.2
c.3
d.4

98. Type of extended-release formulation that follows C


zero-order kinetics
a.Immediate-release
b.Sustained-release
c.Controlled-release
d.Target-release

99. Flow system that shows a yield value A


a.Plastic
b.Pseudoplastic
c.Dilatant
d.Newtonian

100. Which example of bulk powder contains a soap, mild D


abrasive agent and anticariogenic agent?
I. Dentifrices
II. Dusting Powders
III. Douche Powders
IV. Insufflations
V. Triturations
a.V
b.III
c.II
d.I

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