Valproic

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DRUG STUDY

GROUP: 2D
VALPROIC ACID AREA: PSYCHIATRIC WARD
YR
BSN 3-Y2-6 DATE: 04/04/24 CLINICAL INSTRUCTOR:
LEVEL &
SEC:
MECHANISM
DRUG NAME CLASSIFICATI INDICATION CONTRADICTIO ADVERSE NURSING
ON OF N REACTION RESPONSIBILITIES
ACTION
GENERIC Therapeutic class: Route: Adjust-a-dose (for all Contraindicated in patients CNS: asthenia, Closely monitor all patients taking or starting
NAME: Anticonvulsants PO indications): For elderly hypersensitive dizziness, drowsiness, antiepileptic drugs for changes in behavior
patients, start at lower to drug and in those with head-ache, insomnia, indicating worsening of suicidal thoughts or
VALPROIC Pharmacologic class: dosage. Increase dosage hepatic disease or nervousness, behavior or depression.
ACID Carboxylic acid Onset: more slowly and with significant hepatic somnolence, tremor,
derivatives Unknown regular monitoring of fluid dysfunction, and in pa- abnormal thinking, Symptoms such as anxiety, agitation,
AVAILABLE and nutritional intake, and tients with a urea cycle amnesia, ataxia, hostility, ma-nia, and hypomania may be
watch for dehydration, disorder (UCD). depression, emotional precursors to emerging suicidality.
FORMS: Peak: somnolence, and other ace- upset, fever, abnormal
Capsule: 5 mg Variable verse reactions. - dreams. Adverse reactions may not be caused by
valproic acid alone because it's usually used
Duration: with other anticonvulsants.
Unknown
Notify prescriber if tremors occur; a dosage
reduction may be needed.

Monitor drug level. Therapeutic level is


commonly considered to be 50 to 100
mcg/mL for seizure control and 50 to 125
mcg/mL for mania..

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