This document contains 20 multiple choice questions about leprosy. The questions cover topics such as bones affected in leprosy, clinical features of leprosy, treatment history including drugs used such as dapsone and rifampicin, animal models for studying leprosy, and organizations involved in leprosy research and treatment.
This document contains 20 multiple choice questions about leprosy. The questions cover topics such as bones affected in leprosy, clinical features of leprosy, treatment history including drugs used such as dapsone and rifampicin, animal models for studying leprosy, and organizations involved in leprosy research and treatment.
This document contains 20 multiple choice questions about leprosy. The questions cover topics such as bones affected in leprosy, clinical features of leprosy, treatment history including drugs used such as dapsone and rifampicin, animal models for studying leprosy, and organizations involved in leprosy research and treatment.
This document contains 20 multiple choice questions about leprosy. The questions cover topics such as bones affected in leprosy, clinical features of leprosy, treatment history including drugs used such as dapsone and rifampicin, animal models for studying leprosy, and organizations involved in leprosy research and treatment.
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ROUND I- MCQ
LEPROSY Question 1 • Which bones are not involved in leprosy? a) Metatarsals b) Tarsals c) Metacarpals d) Proximal phalanx Question 2 • Pencilling or sucked candy stick is seen in a) Metacarpals b) Carapals c) Tarsals d) Metatarsals Question 3 • “Fascies leprosa” includes a triad of all except a) Atrophy of anterior nasal spine b) Atrophy of and recession of the maxilllary alveolar processes c) Atrophy and recession of the mandibular alveolar processes d) Endonasal inflammatory changes Question 4 • Which part of testes is involved first in leprosy? a) Leydig cells b) Seminiferous tubules c) Rete testes d) Interstitial cells Question 5 • What is the % of Indian leprosy patient developing renal amyloidosis? a) 0-15% b) 20-25 % c) 30-35% d) 40-45% Question 6 • Which of the following gland is affected in leprosy ? a) Parathyroid b) Pancreas c) Adrenal gland d) Pituitary Question 7 • When was IRIS association with leprosy first described ? a) 2001 b) 2003 c) 2005 d) 2007 Question 8 • Chaulmoogra oil is obtained from ___of tree a) Roots b) flower c) Bark d) Seeds Question 9 • When was Dapsone first synthesized ? a) 1947 b) 1934 c) 1952 d) 1908 Question 10 • Genetic basis of Dapsone resistance lies in mutation of ___codon of folPgene of M.Lepra a) 351 b) 531 c) 55 d) 46 Question 11 • Mutation in folP gene responsible for Dapsone resistance results from substitution of ___ for ____ amino acid ? a) Proline for leucine b) Leucin for proline c) Methionine for valine d) Valine for methionine Question 12 • Rifampicin is obtained from a) Streptomyces venezuelae b) Streptomyces griseus c) Streptomyces mediterranei d) Streptomyces rimosus Question 13 • Rifampicin resistance is due to mutation in which codon on RpoB gene ? a) 351 b) 531 c) 55 d) 47 Question 14 • DL -473 is a) Rifabutin b) Rifapentine c) Rifamycin d) Rifampicin Question 15 1ST successful experimental infection of non human primate was of a. Chimpanzees b.Sooty mangabey c. Gibbon d.None Question 16 • Bactrin is a) Fluoroquinlone b) Macrolide c) Sulphonamide d) Ansamycins Question 17 Promin is a) Fluoroquinlone b) Macrolide c) Sulphonamide d) Ansamycins Question 18 • Dapsone was first used for treatment of leprosy by a) Cochrane b) Lowe and smith c) Guy Faget d) Brown and hogrerzeil Question 19 Revimid is a) Thalidomide b) Macrolide c) Sulphonamide d) Ansamycins Question 20 • Following splints are used in deformity in leprosy except a) Abductor band splint b) Finger loop splint c) Opponens loop splint d) Gutter splint ROUND II- Questions Question 1 • ‘ Fascies leprosa’ was described by Danish physician named____ Answer 1 • Moller Christensen Question 2 • Chaulmoogra oil is also called as Answer 2 • Hydnocarpus oil Question 3 • POWD stands for • Prevention of worsening of disabilities Question 4 What are the spared area of ENL lesion ? Answer 4 • Hairy scalp , axilla, groin and perineum Question 5 • What is IDEAL ? Answer 5 • ‘Initiative for Diagnostic and Epidemiological Assays for Leprosy’ Question 6 Who suggested use of Armadillos as a model for leprosy ? Answer 6 Storrs Question 7 • Best model to study neuropathology in leprosy is Answer 7 • Nude mice Question 8 • Viable leprosy bacilli can survive in dried nasal secretions upto 7 days Question 9 • Who introduced nude mice in leprosy research ? Prabhakaran Question 10 • Naturally acquired leprosy in animals was discovered by Walsh Question 11 • What does NLR stand for ? • Netherlands Leprosy Relief Question 12 • Name 2 other mycobacteria , other than M. vaccae which have antigenic similarity with M.Lepra • M. Habana • M . Phlei • M. Gordonnae Question 13 • National Leprosy Control programme was launched in ? • 1953 Question 14 • What is the average normal perception threshold for nylon filament at finger pulp? • 0.217 gm/mm2 Question 15 • What does LEPRA stand for • British leprosy relief association Q 16 Identify • Rudolf Virchow Q 17. Identify • Beige mice - suitable for chemotherapy studies in leprosy Q 18. Name the family of this species • EDENTATA- family • Dasypus novenmcinctus Q 19. • The initial entry of M Leprae into Schwann cell is by binding? Answer • Laminin α- 2 chain Q 20. Connect • Anandwan ( forest of joy) was the first leprosy ashram started by Babe Amte. • It is located in the remote jungles of Warora , in Chandrapura distt. of Maharashtra about 100 km from Nagpur. • Other ashrams started by Babe Amte : Somnath & Ashokvan ashrams Q 17.Connect
