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    Ehrlichiosis HVK1602

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    kamal
    This document discusses canine ehrlichiosis, caused by the bacterium Ehrlichia canis, which infects dogs. It is transmitted by the brown dog tick. The main symptoms are fever, lack of appetite, enlarged lymph nodes, coughing, and difficulty breathing. Laboratory tests may show low blood cell counts. A blood smear can detect morulae inside white blood cells, confirming the diagnosis. Treatment involves antibiotics like doxycycline or tetracycline for several weeks. With treatment, the dog's condition should improve over time.

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    Ehrlichiosis HVK1602

    Uploaded by

    kamal
    12 views23 pages
    This document discusses canine ehrlichiosis, caused by the bacterium Ehrlichia canis, which infects dogs. It is transmitted by the brown dog tick. The main symptoms are fever, lack of appetite, enlarged lymph nodes, coughing, and difficulty breathing. Laboratory tests may show low blood cell counts. A blood smear can detect morulae inside white blood cells, confirming the diagnosis. Treatment involves antibiotics like doxycycline or tetracycline for several weeks. With treatment, the dog's condition should improve over time.

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    EHRLICHIOSIS HVK1602

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    This document discusses canine ehrlichiosis, caused by the bacterium Ehrlichia canis, which infects dogs. It is transmitted by the brown dog tick. The main symptoms are fever, lack of appetite, enlarged lymph nodes, coughing, and difficulty breathing. Laboratory tests may show low blood cell counts. A blood smear can detect morulae inside white blood cells, confirming the diagnosis. Treatment involves antibiotics like doxycycline or tetracycline for several weeks. With treatment, the dog's condition should improve over time.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    12 views23 pages

    Ehrlichiosis HVK1602

    Uploaded by

    kamal
    This document discusses canine ehrlichiosis, caused by the bacterium Ehrlichia canis, which infects dogs. It is transmitted by the brown dog tick. The main symptoms are fever, lack of appetite, enlarged lymph nodes, coughing, and difficulty breathing. Laboratory tests may show low blood cell counts. A blood smear can detect morulae inside white blood cells, confirming the diagnosis. Treatment involves antibiotics like doxycycline or tetracycline for several weeks. With treatment, the dog's condition should improve over time.

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    CANINE EHRLICHIOSIS

    SUBMITTED BY: SUBMITTED TO:


    AKASH H R DEPT. OF VLD
    HVK1602
    About the patient
    • Case number:17163
     Animal: Dog
    Species: Canine
    • Breed: German shepherd
     Sex: female
    Age: 4 yrs
     Body weight: 24kg
    Owner’s complaint
     Reported that animal is having severe dry
    cough started 2 days back. feed intake is decresed

    History
     No history of cough reported earlier.
     Vaccination & deworming proper.
    OBSERVATIONS
     Animal was active and alert.
     On auscultation tracheal sounds highly
    exaggerated. Palpation of trachea elicited
    cough.
     Lung sounds exaggerated. Heart sounds
    masked by lung sounds.
     Pre-scapular & sub-maxillary lymph nodes
    enlarged.
    OBSERVATIONS
     Respiration rate: 102/min.(15-25)
     Pulse: 100/min (100-130)
     Temperature: 103.2°F
     MM: slightly congested
     Palpation of pharynx revealed no
     structural abnormalities.
    RESULT OF LABORATORY EXAMINATION
     Faecal sample: negative for ova of
    parasites
     Blood smear: E.canis morulae could
    be seen in the monocytes.
     Blood smear: No bacteria of
    pathogenic significance could be seen.
    RESULT OF LABORATORY EXAMINATION
     Hb - 10 g%(12-18)
     ESR- 1mm/hr (5-15)
     TLC - 7300/cmm (6000-17000)
     RBC - 4.3 million/cmm (5.5-8.5)
     Band cell – 2% (0-3%)
     Eosinophil – 3% (2-10%)
     Monocyte – 3% (3-10%)
     Lymphocyte – 13%(12 – 30 %)
     Neutrophil – 79% (60-70%)
    TREATMENT
    Inj. 5D -250ml -I/V
    Inj, FPP -3.3ML -I/M
    Inj. Rantac -2ml -S/C
    Inj. Perionorm -2ml –I/M
     Tab. DoxyI 100mg × 10
    Sig. 1tab daily orally
    (Doxycycline @ 5mg/kg BID PO
    Glycodine syrup × 1
    Sig. 2 tsp BID orally
    Animal was brought 2 days after &
    there was slight improvement in the
    condition.
    Temperature -104°F
    Pulse – 98/ min
    Respiration - panting
    Advised the owner to continue the
    treatment for 3 days.
    R×
    Tab DoxyI 100mg × 24
    Sig 1tab BID orally
    Follow-up
    Animal showed improvement in
    condition &
    the cough was reduced & stopped.
    CANINE EHRLICHIOSIS
    Etiology
    Ehrlichia canis affecting wild &
    domestic canids.
     Tropism for circulating leukocytes.
     Replicate in the phagosomes of leukocytes
    STAGES IN LIFE CYCLE
     Elementary body
     Initial body
     Morulae
    Transmission: by tick
    bite.
    Vector: Rhipicephalus
    sanguineus
    PATHOGENESIS
     Commonly called Canine monocytic
    ehrlichiosis.
     Incubation period:8-20 days.
     ACUTE PHASE: Rapid multiplication in
    the WBCs, spreads throughout the body
    reaching various parenchymatous organs
    like lungs, liver etc. In this phase symptoms
    are manifested.
    lab findings in acute phase:
    Anaemia, leukaemia, Thrombocytopaenia

    Mechanisms of
    thrombocytopaenia:
    1.Increased platelet consumption by
    endothelial blood vessels.
    2.Increased platelet destruction by spleen.
    3.Antiplatelet antibodies.
    CHRONIC PHASE:
    Bone marrow depression or bone
    marrow
    hypoplasia – reduction in all type of
    cells.
     Tropical canine pancytopaenia
    Very low parasitaemia at this stage.
    CLINICAL FINDINGS
     Due to involvement of hemic &
    lymphoreticular systems.
     Commonly progress from acute to
    chronic
    depending on
    - Strain of the organism.
    - Immune status of the animal.
    - Improper treatment.
    In Acute cases: Fever, anorexia,
    depression, lymph node enlargement,
    reluctance to walk, edema of limbs,
    coughing, dyspnoea, polyarthritis,
    diarrhoea etc.
    Chronic cases: marked spleenomegaly,
    renal failure, interstitial pneumonitis,
    cerebellar ataxia, depression, paresis,
    severe weight loss.
    Lesions
    Spleenomegaly, lymphadenopathy,
    haemorrhage in the liver, kidney, GIT.
    DIAGNOSIS
    - Symptoms
    -Demonstration of organisms (morulae)
    with in the WBCs in blood smear or buffy
    coat smear.(Giemsa stain)
    -Indirect immuno fluorescence test
    -Molecular diagnosis- PCR
    DIFFERENTIAL DIAGNOSIS

    Acute cases: Hepatozoon canis, Babesia


    canis, Haemobartonella
    canis,Lymphadenopathy.
    Chronic cases: Immune mediated pan
    cytopaenia, other diseases associated with
    specific organs like glomarulo nephritis.
    TREATMENT
     Tetracyclines – 10-20mg/Kg parenterally
    for 14 days, 22mg/Kg TID orally for 2
    weeks in acute cases & 1-2 months in
    chronic cases
     Doxycycline – 5-10mg/Kg PO or i/v for
    10-14 days (if tetracycline fails or in old
    dogs with kidney problems)
    Supportive therapy to combat wasting &
    specific organ dysfunction.
    THANK YOU

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