Station 3 Leaflet

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Common medications for COAD / asthma

Name of medications Route of Paediatrics Paediatrics Adults


administrati (< 5 years old) (> 5 years old)
on
Salbutamol (50mg in 10ml) Nebulisation o.o3ml/kg salbutamol + remaining ml NS 1ml + 3ml NS / 2ml + 2ml NS
Atrovent (ipratropium) Nebulisation
• 0.5mg/2ml • 1ml +3ml NS • 2ml + 2ml NS • 2ml + 2ml NS
• 0.25mg/2ml • 2ml + 3ml NS • 4ml • 4ml
AVN Nebulisation
A: Atrovent • A : 0.25mg/2ml • A: 0.5mg/2ml • A: 0.5mg/2ml
V: Ventholin V : o.o3ml/kg V : o.o3ml/kg V: 1ml (5mg)
N: Normal saline N : NS remaining ml N : NS remaining ml N: 1ml NS

Combivent (ipratropium 0.5mg + Nebulisation 1ml + 3ml NS 2ml + 2ml NS 4ml (pure 2 vials)
salbutamol 2.5mg)
*severe cases*
Budesonide Nebulisation • In Croup : 2mg stat (4ml) = 2 vials 2ml (1 vial) + 1ml salbutamol
• Others: 2ml (1 vial) + o.o3ml/kg salbutamol + + 1ml NS
remaining ml NS
Name of medications Route of Paediatrics Paediatrics Adults
administration (< 5 years old) (> 5 years old)
Magnesium Sulphate Intravenous 50mg/kg (25-75mg/kg) over 20mins 2.47g in 20ml over 20mins
(2.47g in 5ml) (1 vial must be diluted minimum of 7.5ml solution)
Hydrocortisone Intravenous 4mg/kg 4mg/kg 200mg stat in 20ml NS
(100mg dilute in 10ml NS)
Prednisolone Oral 1mg/kg 1mg/kg 1mg/kg (up to 60mg)
(0.5-1.0ml/kg/day)
Salbutamol Intravenous Infusion 3-20mcg/min
(0.5mg/ml) (max: 20mcg/min)
Respiratory failure : 5mcg/min
6 vials = 3mg/ml = 6ml
჻ 6ml + 44ml NS 0.9% = 50ml
Aminophylline* Intravenous Infusion *not recommended* Loading dose:
(250mg/10ml) • 5.7mg/kg over 30mins
>> up to 250mg : dilute in
**if pt have theophylline tx, to 50ml NS 0.9% (1 vial)
check for serum theophylline >> 250-500mg: dilute in
concentration 100ml NS 0.9% (2 vials)
LD = (concentration desired –
measured) x Vd
Maintenance dose:
• 2 vials = 500mg/20ml
Initial settings
for ventilator
for COPD /
asthma patient
WHEN TO SUSPECT AUTO-PEEP? MANAGEMENT WHEN
1. Increasing plateau pressures on the ventilator. SUSPECTING AUTO-PEEP?
2. Flow time scalar on Ventilator - doesn’t reach baseline

3. Active exhalation by the patient as seen by the use of 1. Reduce the RR


accessory muscles of respiration during exhalation.
2. Change I:E – prolong the expiratory
4. Drop-in blood pressure.
time
5. Long expiratory times.
3. Check Pplat FREQUENTLY – Pplat
6. Respiratory distress

<30mmhg

4. Set a low amount PEEP

5. Allow Permissive Hypercapnia

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