Mdm2 directs the ubiquitination of beta-arrestin-sequestered cAMP phosphodiesterase-4D5 (Q24316484)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19372219%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

29 December 2023

https://doi.org/10.1074/jbc.W120.015374

https://retractionwatch.com/2021/11/23/university-of-glasgow-in-discussions-to-retract-seven-papers-confirming-retraction-watch-reporting/

title

Mdm2 directs the ubiquitination of beta-arrestin-sequestered cAMP phosphodiesterase-4D5 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19372219%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

0 references

1 reference

Arginine vasopressin receptor 2

1 reference

Arrestin beta 2

1 reference

MDM2 proto-oncogene

1 reference

ubiquitin protein ligase activity

1 reference

Transformed mouse 3T3 cell double minute 2

1 reference

protein ubiquitination

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19372219%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Miles D. Houslay

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19372219%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Xiang Li

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19372219%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

language of work or name

English

0 references

publication date

16 April 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19372219%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

26 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19372219%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19372219%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19372219%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

16170-16182

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19372219%20AND%20SRC:MED&resulttype=core&format=json

MDM2 regulates dihydrofolate reductase activity through monoubiquitination

26 January 2020

cites work

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The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579.

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Characterization of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene

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1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1

19 March 2017

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DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling

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Keynote review: phosphodiesterase-4 as a therapeutic target

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Structure of the Ubiquitin-interacting Motif of S5a Bound to the Ubiquitin-like Domain of HR23B

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Solution structure of Vps27 UIM-ubiquitin complex important for endosomal sorting and receptor downregulation

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Structure and Ubiquitin Binding of the Ubiquitin-interacting Motif

19 March 2017

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beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi

19 March 2017

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Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins

19 March 2017

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Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin

19 March 2017

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Mechanisms underlying ubiquitination

19 March 2017

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Phosphodiesterase 4D and protein kinase a type II constitute a signaling unit in the centrosomal area

19 March 2017

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Themes and variations on ubiquitylation

19 March 2017

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Assembly of an A kinase-anchoring protein-beta(2)-adrenergic receptor complex facilitates receptor phosphorylation and signaling

19 March 2017

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Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B. Consequences for rolipram inhibition

19 March 2017

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Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation

19 March 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation

27 September 2017

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p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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The unique amino-terminal region of the PDE4D5 cAMP phosphodiesterase isoform confers preferential interaction with beta-arrestins

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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cAMP-specific phosphodiesterase HSPDE4D3 mutants which mimic activation and changes in rolipram inhibition triggered by protein kinase A phosphorylation of Ser-54: generation of a molecular model.

27 September 2017

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Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates

27 September 2017

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In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region

27 September 2017

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Cyclic nucleotide research -- still expanding after half a century

30 May 2018

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Specific role of phosphodiesterase 4B in lipopolysaccharide-induced signaling in mouse macrophages

21 January 2018

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Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells.

21 January 2018

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The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation

21 January 2018

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E3-independent monoubiquitination of ubiquitin-binding proteins.

21 January 2018

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21 January 2018

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UCR1 and UCR2 domains unique to the cAMP-specific phosphodiesterase family form a discrete module via electrostatic interactions.

21 January 2018

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Regulation of adenylate cyclase (EC 4.6.1.1) activity by its lipid environment

21 January 2018

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Sensitivity of p53 lysine mutants to ubiquitin-directed degradation targeted by human papillomavirus E6

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19372219

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19372219

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.008078

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19372219%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19372219%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

19372219

2 references