Empozoñamiento Ofídico Diapositivas

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EMPOZOÑAMIENT

EMPOZOÑAMIEN
O OFÍDICO
TO OFÍDICO
Angely Rojas
Dra. Maigualida Rengifo Yolimar Sánchez
Fabio Rondón
Stefany Torres
DEFINICIÓN

“Ponzoña”: Veneno
producido por animal
EPIDEMIOLOGÍA

• 1.8 y 2.7 millones de personas.

• 80.000 a 140.000 fallecen


• 10-40 años

• África subsahariana, Asia y América Latina

• Pico de casos de mayo-julio y octubre-diciembre


EN VENEZUELA

ELAPIDAE VIPERIDAE

Micrurus Bothrops
Lachesis
Crotalus
EN VENEZUELA
ELAPIDAE
Micrurus

Serpientes de coral
• Micrurus isozonus
• Micrurus dissoleucus
EN VENEZUELA
VIPERIDAE
Bothrops Lachesis Crotalus

Mapanare
Lachesis muta muta Cascabel
Manifestaciones clinicas
Accidente bothropico

Dolor en el sitio de la Edema circunscrito Flictenas de contenido


mordedura seroso o serohemático

La necrosis de los Compromiso del Un eventual estado


tejidos estado general de shock
Caracteristicas del edema

Trastornos de los factores de coagulacion


Manifestaciones clinicas
Accidente lachesico

Gastrointestinales Cardiocirculatorias Neurologicas

• Cólicos abdominales • Hipotensión severa, • Ptosis palpebral,


• Diarrea • Lipotimias, • Paresia de los músculos
• Bradicardia de la nuca
• Ruidos cardíacos • Parálisis respiratoria.
hipofonéticos.
Manifestaciones clinicas
Accidentes micruricos

○ isartria
○ crisis de sofocación
○ parálisis de los músculos
respiratorios
○ crisis hipotensiva
○ parálisis flácida de los
miembros
Manifestaciones clinicas
Accidente crotalico

Sistemico
• facies miasténica
• con ptosis palpebral bilateral
• oftalmoplejía
• diplopía
• dificultad para la acomodación
• visión borrosa.

Nefrohemolitico
• anemia
• hemoglobinuria
• albuminuria
• cilindruria
Diagnostico
○ Pruebas de coagulación
• Tiempo Parcial de Tromboplastina ( PTT ).
• Tiempo de Protrombina ( PT ).
• Tiempo de coagulación ( TC ).
• Fibrinógeno.
○ Hemograma
○ Urea y Creatinina
○ Electrolitos
○ Creatinfosfokinasa (CPK) y Deshidrogenasa láctica
(DHL)
○ Examen de orinas
Diagnostico
Identificar
Es fundamental identificar el
tipo de serpiente 50-70% de los
casos

Clinica
Permite la clasificacion del
envenenamiento y la gravedad
del mismo segun el genero de
la serpiente
Tratamiento
Medidas prehospitalarias

Inmovilizar la Limpiar la herida


No realizar No succion de
extremidad con agua o
torniquete la herida
afectada solucion

Movilizar en camilla No realizar No administrar Trasladar a


insisiones bebida que centro de salud
contengal cercano
alcohol
Medida hospitalarias
Vía aérea permeable  Canalizar 2 vía periféricas

A verificar Respiración  Oxigeno por cánula nasal en dificultad


respiratoria
B Verificar pulso y
estado circulatorio  Lavado de la herida con agua o solución

C Déficit neurológico
0,9%

 Corregir hipovolemia administrar líquidos


D Identificar de manera
EV tipo cristaloides
 Control Estrictos De Líquidos Ingeridos Y

E
temprana la presencia Eliminados
de complicaciones  Sona vesical en caso de anuria
SUERO ANTIOFIDICO
POLIVALENTE ANTICORAL

5 frascos casos leves Dosis inicial 10 frascos


10 para moderado y severo
TRATAMIENTO COMPLEMENTARIO
ADMISNISTRACCION DE SUERO ANTIOFIDICO
• Para el dolor morfina 0,03 mg/kg
• Agregar dosis a administrar en 500 ml de sol salina
• Goteo lento c8h V.O
• Reabcciones adversas en 15 min vigilar Antibiótico y profilaxis del tétano
• Gentamicina 650mg EV
• Si no aparecen pasar en 1 h
• Cefixime 400 mg c/24 h V.O
DISORDERS WORLDWIDE

NEPTUNE
Neptune is very far
away from Earth

PLUTO
Pluto is considered
a dwarf planet
ICON PACK
“This is a quote, words full of
wisdom that someone
important said and can make
the reader get inspired.”

—SOMEONE
FAMOUS
A PICTURE
REINFORCES
THE CONCEPT
Images reveal large amounts of
data, so remember: use an image
instead of a long text. Your
audience will appreciate it
CLINICAL TRIAL
PRECLINIC PHASE 1 PHASE 2 PHASE 3
LabAL
studies Human safety Expanded safety Efficacy & safety

100% 20% 60% 80%


TRIAL TIMELINE

RESEARCH EXPERIMENTATIO CONCLUSION


Saturn is a gas giant N planet from
Earth is the third S biggest
Jupiter is the
and has rings the Sun and has life planet of them all

PRECLINICA RESULTS
L second
Venus is the Despite being red,
planet from the Sun Mars is a cold place
PHASE 1
The Sun is the star at the center of the Solar System

24,000 20-80
Pluto is now a dwarf planet Participants

80% 6 DAYS
Success rate Experimentation time
TENDENCY
100 PHASE 1 - 35%
Saturn is a gas giant. It's composed of
hydrogen and helium
75

PHASE 2 - 20%
50 Neptune is the farthest planet from the
Sun and the fourth-largest

25 PHASE 3 - 45%
The Sun is the star at the center of the
Solar System
0
Follow the link in the graph to modify its data and then
Phase I Phase II Phase III paste the new one here. More info
RESULTS
TEST 1 TEST 2 TEST 3 TEST 4

GROUP 1 455 23 167 100


EXPERIMEN
TA GROUP 2 567 234 1000 23

GROUP 3 468 897 567 237

TEST 1 TEST 2 TEST 3 TEST 4

GROUP 1 789 309 237 12


EXPERIMEN
TB GROUP 2 349 873 192 50

GROUP 3 598 984 289 40


KEEP TRACK OF THE PROCESS

You can replace the image on


the screen with your own
work. Just right-click on it and
select “Replace image”
RESULTS ANALYSIS
GROUP 1 GROUP 2
Mercury - 100%

Venus - 60%
Neptune Pluto Ceres
Earth - 80%

Mars - 20% GROUP 3


Mercury is the closest planet to the Sun and
Jupiter - 40%
the smallest one in the Solar System. This
planet's name has nothing to do with the liquid
Saturn - 60% metal, since Mercury was named after a god
SUCCESS RATE
Mercury is the closest
planet to the Sun MERCUR 50%
Y
Venus is the second
planet from the Sun VENUS 05%

Earth is the third


planet from the Sun EARTH 15%

Despite being red,


Mars is a cold place MARS 20%

Jupiter is the biggest


planet of them all JUPITER 10%
THANKS
!
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