Papers by Hatemadel Sembawa
Biomedical Journal of Scientific & Technical Research
Growing knowledge supports the importance of microRNAs in cell growth regulation, differentiation... more Growing knowledge supports the importance of microRNAs in cell growth regulation, differentiation, apoptosis, and tumorigenesis. We addressed the associations between miRNA variants and risk of urothelial bladder carcinoma (UBCa). Subjects and Methods: Sixty-six cases with UBCa (33 pTa, 13 pT1, 20 pT2) of low and high tumor grade (21 and 45 cases, respectively), and 156 healthy controls were genotyped for miR-196a2 rs11614913(C>T), miR-146a rs2910164(C>G), and miR-499 rs3746444(A>G) using TaqMan genotyping assays. Patients were stratified according to tumor stage, tumor grade, and risk of recurrence for UBCa. We used the SNPStats (https://www.snpstats.net) to choose best interactive model(s) of inheritance in selected miRNAs. Results: The rs3746444 SNP showed a potential association with risk of UBCa (odds ratio [OR]= 1.9; P= 0.012). Significant associations were found for rs3746444 (P= 0.013) in codominant models, and for rs11614913 (P= 0.048) in an additive model. The rs11614913T allele had a protective effect, while homozygotes for the C allele were associated with a significantly increased risk of UBCa compared with controls (χ2= 3.7; P= 0.05). Homozygosity of rs3746444A/A was more frequent in cases than controls (43.9% versus 30.8%). Despite its significant impact in diverse ethnic populations, the rs29101164 SNP did not show clear effects on UBCa. Besides, the presence of rs3746444A/A was associated with tumors of high grade (OR= 2.7; P= 0.046). Conclusion: This study was the first among the Saudi community to present a substantial function of miRNA biomarkers to predict UBCa, identify at-risk patients, and suggest a potential therapeutic target for UBCa.
Journal of Education and Learning
The aim of the study was to evaluate the benefits from 4th year surgical course for medical stude... more The aim of the study was to evaluate the benefits from 4th year surgical course for medical students upon reaching 6th year surgical course. A questionnaire survey was conducted and questions regarding student satisfaction with the 4th year course and the benefits gained from this course in the 6th year were evaluated. Students were questioned regarding their interest in surgery as a career. A total of 67 students were enrolled in the study and the information collected from them was analyzed. The results showed that only 35 students reported in agreement of offering 1 surgery course; whereas, only 32 students reported in agreement of 2 surgery courses. The results also showed that only 26 students were interested in surgery as a career. The study emphasized on spreading awareness among students regarding surgery, and suggested that courses must be introduced in the curriculum to help students in their future decision making.
Canadian journal of surgery. Journal canadien de chirurgie, 2008
I ntestinal carcinoids are an uncommon neoplasm, and multiple carcinoids are extremely rare. Carc... more I ntestinal carcinoids are an uncommon neoplasm, and multiple carcinoids are extremely rare. Carcinoids of the ileum account for 15.4% of all gastrointestinal carcinoids 1 and are multicentric in 20%-30% of patients. We present the first published report of patients with more than 40 carcinoids in the terminal ileum. In both patients, the carcinoids were associated with extraintestinal neoplasms. Our findings support the association of carcinoids with other neoplastic conditions.
Journal of Education and Learning
The aim of the study was to evaluate the benefits from 4th year surgical course for medical stude... more The aim of the study was to evaluate the benefits from 4th year surgical course for medical students upon reaching 6th year surgical course. A questionnaire survey was conducted and questions regarding student satisfaction with the 4th year course and the benefits gained from this course in the 6th year were evaluated. Students were questioned regarding their interest in surgery as a career. A total of 67 students were enrolled in the study and the information collected from them was analyzed. The results showed that only 35 students reported in agreement of offering 1 surgery course; whereas, only 32 students reported in agreement of 2 surgery courses. The results also showed that only 26 students were interested in surgery as a career. The study emphasized on spreading awareness among students regarding surgery, and suggested that courses must be introduced in the curriculum to help students in their future decision making.
Multiple Choice Question ( MCQ ) is used in assessing and evaluating the educational process worl... more Multiple Choice Question ( MCQ ) is used in assessing and evaluating the educational process worldwide as well as medical schools in Saudi Arabia. The Study is cross-sectional study was carried out in 278 medical students at Umm Al-Qura University, Makkah, Saudi Arabia. Data was collected by using a ?pre-tested? semi-structured questionnaire. The data were analyzed using SPSS Version 11 statistical. There are four main reasons that make MCQ exam difficult to students. There are aproblem in studying methods,problem in teaching technique,problem in the giving curriculum and problem in the language. Other difficulties in answering MCQ exam related to the way of questions include: problems in the content of thequestion, problems in the level of the exam, problems in answer options and problems in recalling.Also, the time given is insufficient or difficulties in time organization during exam one of main problems. There are some external problems such as separated answering sheet, anxiety symptoms, eating and sleeping before theexam.
- See more at: http://www.journalijar.com/article/17831/difficulties-in-answering-multiple-choice-questions-among-umm-al-qura-medical-students,makkah,-saudi-arabia./#sthash.wRrCPovF.dpuf
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Papers by Hatemadel Sembawa
- See more at: http://www.journalijar.com/article/17831/difficulties-in-answering-multiple-choice-questions-among-umm-al-qura-medical-students,makkah,-saudi-arabia./#sthash.wRrCPovF.dpuf
- See more at: http://www.journalijar.com/article/17831/difficulties-in-answering-multiple-choice-questions-among-umm-al-qura-medical-students,makkah,-saudi-arabia./#sthash.wRrCPovF.dpuf