Pridefine

Pridefine

Systematic (IUPAC) name
3-(Diphenylmethylidene)-1-ethylpyrrolidine
Clinical data
Legal status	Uncontrolled
Routes of administration	Oral
Identifiers
CAS Number	5370-41-2
ATC code	none
PubChem	CID: 31740
ChemSpider	29434
UNII	W0394470AX Y
Chemical data
Formula	C19H21N
Molecular mass	263.38 g/mol

Pridefine (AHR-1,118) is a drug which was investigated as an antidepressant in the late 1970s and early 1980s, but was never marketed. It acts as a balanced reuptake inhibitor of serotonin, dopamine, and norepinephrine, and also has some weak releasing activity.

In clinical trials pridefine was found to be as efficacious as the tricyclic antidepressants amitriptyline and imipramine in the treatment of major depressive disorder but was much more tolerable in comparison and also had an earlier onset of action. It has been shown to be effective in the treatment of alcoholism as well.

See also

• Desoxypipradrol
• Diphenylprolinol
• Pipradrol