Clopenthixol

Clopenthixol

Systematic (IUPAC) name
(E,Z)-2-[4-[3-(2-chlorothioxanthen-9-ylidene) propyl]piperazin-1-yl]ethanol
Clinical data
Routes of administration	Oral
Identifiers
CAS Number	982-24-1 N
ATC code	N05AF02 (WHO)
PubChem	CID: 12454
ChemSpider	11945 N
UNII	FLE878A8ZI N
KEGG	D02613 N
ChEMBL	CHEMBL53904 N
Chemical data
Formula	C22H25ClN2OS
Molecular mass	400.965 g/mol
SMILES Clc2cc1C(c3c(Sc1cc2)cccc3)=CCCN4CCN(CCO)CC4
NY (what is this?)  (verify)

Clopenthixol (Sordinol), also known as clopentixol, is a typical antipsychotic drug of the thioxanthene class. It was introduced by Lundbeck in 1961.

Clopenthixol is a racemic mixture of cis and trans isomers. Zuclopenthixol, the pure cis isomer, was later introduced by Lundbeck in 1962, and has been much more widely used. Both drugs are equally effective as antipsychotics and have similar adverse effect profiles, but clopenthixol is half as active on a milligram-to-milligram basis and appears to produce more sedation in comparison.

Clopenthixol is not approved for use in the United States.

See also

• Typical antipsychotic
• Thioxanthene

External links

• Clopenthixol at the US National Library of Medicine Medical Subject Headings (MeSH)