SHA-68

SHA-68
Systematic (IUPAC) name
	N-[(4-fluorophenyl)methyl]-3-oxo-1,1-diphenyl-5,6,8,8a-tetrahydro-[1,3]oxazolo[3,4-a]pyrazine-7-carboxamide
Identifiers
ATC code	none
PubChem	CID: 11374217
IUPHAR/BPS	5813
ChemSpider	9549134
ChEMBL	CHEMBL469695
Chemical data
Formula	C26H24FN3O3
Molecular mass	445.484 g/mol
	SMILES c4ccccc4C1(c5ccccc5)OC(=O)N3C1CN(CC3)C(=O)NCc(cc2)ccc2F ;
	InChI InChI=1S/C26H24FN3O3/c27-22-13-11-19(12-14-22)17-28-24(31)29-15-16-30-23(18-29)26(33-25(30)32,20-7-3-1-4-8-20)21-9-5-2-6-10-21/h1-14,23H,15-18H2,(H,28,31) ; Key:SFRQIPRTNYHJHP-UHFFFAOYSA-N ;
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SHA-68 is a drug which acts as a selective, non-peptide antagonist at the neuropeptide S receptor NPSR. In animal studies it has anxiogenic effects, and blocks the stimulant action of neuropeptide S.^[1]^[2]

References

↑ Fukatsu K, Nakayama Y, Tarui N, Mori M, Matsumoto H, Kurasawa O, Banno H. Bicyclic Piperazine Compound and Use Thereof. PCT Patent WO 2005/021555 A1. Published 26.08.2004
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