Teniloxazine

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Teniloxazine
Teniloxazine.svg
Systematic (IUPAC) name
2-{[2-(thiophen-2-ylmethyl)phenoxy]methyl}morpholine
Clinical data
Legal status
  • ℞ (Prescription only)
Routes of
administration		 Oral
Identifiers
CAS Number 62473-79-4 N
62473-80-7 (maleate)
ATC code None
PubChem CID: 119114
ChemSpider 106426 YesY
UNII 95Q6WNP25P YesY
Synonyms Y-8894
Chemical data
Formula C16H19NO2S
Molecular mass 289.393 g/mol
  • O1CCNCC1COc2ccccc2Cc3sccc3
  • InChI=1S/C16H19NO2S/c1-2-6-16(19-12-14-11-17-7-8-18-14)13(4-1)10-15-5-3-9-20-15/h1-6,9,14,17H,7-8,10-12H2 YesY
  • Key:OILWWIVKIDXCIB-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

Teniloxazine (Lucelan, Metatone), also known as sufoxazine/sulfoxazine, is a drug which is marketed in Japan.[1] Though initially investigated as a neuroprotective and nootropic agent for the treatment of cerebrovascular insufficiency in the 1980s,[2][3][4][5][6][7][8][9] it was ultimately developed and approved as an antidepressant instead.[10] It acts as a potent norepinephrine reuptake inhibitor, with fair selectivity over the serotonin and dopamine transporters, and also behaves as an antagonist at the 5-HT2A receptor.[7][10][11]

See also

References

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  9. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  10. ↑ 10.0 10.1 Lua error in package.lua at line 80: module 'strict' not found.
  11. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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