ADP-sugar diphosphatase

ADP-sugar diphosphatase
Identifiers
EC number	3.6.1.21
CAS number	Template:CAS
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, an ADP-sugar diphosphatase (EC 3.6.1.21) is an enzyme that catalyzes the chemical reaction

ADP-sugar + H₂O $\rightleftharpoons$ AMP + alpha-D-aldose 1-phosphate

Thus, the two substrates of this enzyme are ADP-sugar and H₂O, whereas its two products are AMP and alpha-D-aldose 1-phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is ADP-sugar sugarphosphohydrolase. Other names in common use include ADP-sugar pyrophosphatase, and adenosine diphosphosugar pyrophosphatase. This enzyme participates in 3 metabolic pathways: fructose and mannose metabolism, purine metabolism, and starch and sucrose metabolism.