SIB-1893

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SIB-1893
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Systematic (IUPAC) name
(E)-2-methyl-6-(2-phenylethenyl)pyridine
Identifiers
CAS Number 6266-99-5 YesY
PubChem CID: 235382
ChEMBL CHEMBL88612 N
Chemical data
Formula C14H13N
Molecular mass 195.259 g/mol
  • c1ccccc1\C=C\c(nc2C)ccc2
 NYesY (what is this?)  (verify)

SIB-1893 is a drug used in scientific research which was one of the first compounds developed that acts as a selective antagonist for the metabotropic glutamate receptor subtype mGluR5.[1] It has anticonvulsant and neuroprotective effects,[2] and reduces glutamate release.[3] It has also been found to act as a positive allosteric modulator of mGluR4.[4]

References

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  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.



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