Zibotentan
From Infogalactic: the planetary knowledge core
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| Names | |
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| IUPAC name
N-(3-Methoxy-5-methylpyrazin-2-yl)-2-[4-(1,3,4-oxadiazol-2-yl)phenyl]pyridine-3-sulfonamide
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| Other names
ZD4054
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| Identifiers | |
186497-07-4  |
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| ChemSpider | 8085875  |
| 3539 | |
| Jmol 3D model | Interactive image |
| PubChem | 9910224 |
| UNII | 8054MM4902 |
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| Properties | |
| C19H16N6O4S | |
| Molar mass | 424.44 g·mol−1 |
| Vapor pressure | {{{value}}} |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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 verify (what is ?) |
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| Infobox references | |
Zibotentan (INN) (earlier code name ZD4054) is an anti-cancer candidate.[1] It is an endothelin receptor antagonist.[2]
It failed a phase III clinical trial for prostate cancer[3] but other trials are planned.[4] Tolerability of zibotentan plus docetaxel has been evaluated.[5]
References
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ http://www.fiercebiotech.com/story/azs-zibotentan-flunks-late-stage-prostate-cancer-trial/2010-09-27
- ↑ http://www.genengnews.com/gen-news-highlights/pfizer-astrazeneca-and-actelion-separately-report-phase-iii-trial-failures/81243985/
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
External links
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