Tumor of The Eye

TUMORS OF THE EYE
NURHAIDA DJAMIL
FAKULTAS KEDOKTERAN UNIVERSITAS ISLAM SUMATERA UTARA MEDAN 2012
EYE TUMOR NURHAIDA DJAMIL 3/2/2013
Introduction
2
Tumor mata dapat : * Be live threatening
* mengurangi penglihatan
* Penyebab Masalah kecantikan
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Eye Tumor Classification

3
External : on palpebra, conjunctiva, cornea and lacrimal sac. Intraocular Orbital
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Benign External Eye Tumor

4
Dermoid cyst and dermoid tumor Xanthelasma Millium Papilloma Nevus Verruca vulgaris = Common wart Molluscum contagiosum
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Malignant External Tumor

5
Carsinoma in situ Basal cell carcinoma Squamous cell carcinoma Aquired melanosis Lacrimal sac tumor
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Intraocular Eye Tumor

6
1. Malignant melanoma. 2. Retinoblastoma. 3. Uveal metastatic tumor.
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Orbital Tumor (1)

7
Hemangioma Neurogenic Tumor : * Optical nerve glioma * Meningioma * Neurofibroma Rhabdomysarcoma
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Orbital Tumor (2)

8
Lacrimal gland tumor : * Benign mixed tumor * Adenoid cystic carcinoma Metastatic tumor Malignant lymphoma Idiopathic orbital inflammatory desease Dysthyroid ophthalmopathy
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Dermoid Cysts
9
Congenital tumor Dinding tumor terdiri dari dermis dan lapisan epidermis Lokasi : supero-temporal Tumor palpation : tegas , bulat , dan lembut , mobile under the skin. T/ : In toto excision
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Dermoid Cysts
10
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Dermoid Tumor
11
Congenital, lokasi di limbus Terdiri dari jaringan ikat dengan folikel rambut dan kelenjar sebaceous, berdinding oleh epitel skuamosa berlapis Signs : padat, mulus, bulat, menonjol massal, keputihan dalam warna T/ : excision
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Dermoid Tumor
12
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Papilloma
13
Location : margo palpebra and limbus Signs : massa tumor merupakan seperti kembang kol- dan pedunkulata Ukuran tumor yang besar dapat menyerupai keganasan Memiliki kecenderungan tumbuh kembali Infeksi virus. T/ : In toto excision.
Verruca vulgaris
14
Not a true tumor Etiology : viral Shape : various T/ : excision
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Molluscum Contagiosum
15
Etiology : a pox viral Signs : kecil, pucat, lilin , nodul umbilicated T/ : excision
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Basal Cell Carsinoma

16
Dikenal sebagai Basal cell epithelioma 90% di kelopak mata Age 50-55 y, particularly men Signs : ulcerative small node, with elevated border Rarely cause metastasis
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Basal Cell Carsinoma: Therapy

17
Eksisi luas dengan 2 mm batas keamanan, dikendalikan oleh potongan bekuRadiotherapy Cryotherapy Mohs Chemosurgery Curetage and electrodessication
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Squamous Cell Carsinoma

18
2 - 9 % of eyelid malignancies Lebih agresif dibanding dengan BCC Pertumbuhan lambat Metastasis ke regio kelenjar lymph Sign : plaque-like, nodular, ulcerating tumor T/ : similar to basal cell carcinoma
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
19
Intraocular Malignant Melanoma
Iris Melanoma : 6-8%
Uveal melanoma : 9%
Choroidal Melanoma : 85%
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Retinoblastoma
20
Primer yang paling umum, ganas, tumor intraokular masa kanak-kanak Occurring in about 1:20.000 live birth Tidak ada kecenderungan jnis kelamin Sebagian besar menjadi klinis jelas sebelum usia 3 tahun
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
21
Genetic Aspects of Retinoblastoma
Non heritable account for 60% of cases Tumor muncul di tingkat somatik dalam sel retina tunggal Dapat diwariskan memperhitungkan 40% dari kasus. Sel-sel retina primitif cenderung untuk transformasi ganas Hanya 6% memiliki riwayat keluarga yang positif
Presentation of Retinoblastoma
22
Leukocoria (white pupillary reflex), in about 60% cases. Strabismus, in 20% of cases Secondary glaucoma Anterior segment invasion
EYE TUMOR
Orbital inflamation Proptosis Metastasis (regn. LN) Routine exam to risk patients
NURHAIDA DJAMIL
3/2/2013
Signs of Retinoblastoma
23
Awal intraretinal tumor: lesi putih yang datar atau bulat Endofitik tumor: massa putih, kalsifikasi sekunder Exophytic tumor : * Multiglobulated white mass with retinal detachment * perdarahan vitreus
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Retinoblastoma Special Investigations

24
Ultrasonography
CT-Scan : to detect calsification

MRI : to detect optic nerve infiltration
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Retinoblastoma Treatment
25
Unilateral : enukleasi, termasuk sekitar 10 mm dari saraf optik Bilateral : enucleation dari mata yg rusak , irradiation of the fellow eye Pertumbuhan extraocular : excenteration Metastasis : palliative radiotherapy or chemotherapy
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
ENUCLEATION
26
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Capillary Hemangioma
27
Muncul pada bulan pertama setelah kelahiran tanda lahir Strawberry pada kulit palpebra 1st year enlargement followed by regression T/ : * Steroid, low dosage of irradiation * Dysfunction or marked deformity is an indication of excision
Capillary Hemangioma
28
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013
Rhabdomyosarcoma
29
Tumor yang paling umum ganas primer orbital pada anak-anak. Presentation : progresif yang cepat proptosis pada anak-anak 7 tahun usia Sign : Sebuah massa teraba di orbit superior nasal Pembengkakan dan injeksi dari kulit di atasnya, tetapi kulit tidak panas D/ : USG and CT, biopsy T/ : Irradiation and chemotherapy
Rhabdomyosarcoma
30
EYE TUMOR
NURHAIDA DJAMIL
3/2/2013

Tumor of The Eye

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TUMORS OF THE EYE

Tumor mata dapat : * Be live threatening

Eye Tumor Classification

External : on palpebra, conjunctiva, cornea and lacrimal sac. Intraocular Orbital

Benign External Eye Tumor

Malignant External Tumor

Intraocular Eye Tumor

1. Malignant melanoma. 2. Retinoblastoma. 3. Uveal metastatic tumor.

Orbital Tumor (1)

Hemangioma Neurogenic Tumor : * Optical nerve glioma * Meningioma * Neurofibroma Rhabdomysarcoma

Orbital Tumor (2)

Not a true tumor Etiology : viral Shape : various T/ : excision

Basal Cell Carsinoma

Basal Cell Carsinoma: Therapy

Squamous Cell Carsinoma

Intraocular Malignant Melanoma

Iris Melanoma : 6-8%

Genetic Aspects of Retinoblastoma

Retinoblastoma Special Investigations

CT-Scan : to detect calsification

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