28TH INTERNATIONAL SYMPOSIUM

ON THE AUTONOMIC NERVOUS SYSTEM

Wyndham Grand
Clearwater Beach, Florida
November 1-4, 2017

Preliminary Program

WEDNESDAY, NOVEMBER 1, 2017

8:00 AM-5:00 PM Autonomic Disorders Workshop for Generalists
Dunes I-II
(separate registration required)
3:00-5:00 PM Case Discussion
Dunes I-II
(open to Workshop and AAS Meeting registrants)
5:00-6:30 PM Registration
Dunes Foyer
6:30-9:00 PM Poster Session I and Trainee Poster Competition
Dunes IV-V
(cheese & wine)

THURSDAY, NOVEMBER 2, 2017

8:00-8:30 AM Continental Breakfast
Pelican/Heron
8:30-9:15 AM Robertson Plenary Lecture
Pathophysiology of supine hypertension in autonomic failure
Italo Biaggioni, M.D.
Nashville, TN, USA
Chair: Satish Raj
Dunes I-III
Session 1: Treatment of Orthostatic Hypotension Symposium
Sponsored by Lundbeck
Chairs: Christopher Gibbons, Jens Jordan and Cyndya Shibao
Dunes I-III
9:15-9:30 AM Prospective study of real-world outcomes in the treatment of neurogenic
orthostatic hypotension with droxidopa
S. Kymes, C. François, K. McLeod, A. Duhig, A. Ogbonnaya, A. Quillen, J.
Cannon, C.A. Shibao, B. Yue, I. Biaggioni
Deerfield, IL, USA
9:30-9:45 AM AAS-Lundbeck Travel Fellowship Award
Renal conversion of L-dihydroxyphenylserine (droxidopa) to norepinephrine in
levodopa-untreated patients with neurogenic orthostatic hypotension
G. Lamotte, C. Holmes, P. Sullivan, D.S. Goldstein
Washington, DC, USA
9:45-10:00 AM AAS-Lundbeck Travel Fellowship Award
Vasovagal syncope patients have a reduced quality of life and greater
psychological distress compared to healthy subjects
J. Ng, R.S. Sheldon, D. Ritchie, V. Raj, S.R. Raj
Calgary, AB, Canada
10:00-10:15 AM AAS-Lundbeck Travel Fellowship Award
Initiation of droxidopa during hospital admission for management of refractory
neurogenic orthostatic hypotension in severely ill patients
B. Preheim, J. Celedonio, A. Diedrich, J. Kimmet, J.A.S. Muldowney, A.C. Peltier,
D. Robertson, I. Biaggioni, C.A. Shibao
Nashville, TN, USA
10:15-10:30 AM Effect of acetylcholinesterase inhibition on orthostatic blood pressure and plasma
norepinephrine in individuals with spinal cord injury and uninjured controls
J.M. Wecht, J.P. Weir, N.D. Nguyen, G.J. Schilero, C. Holmes, W.A. Bauman,
D.S. Goldstein
Bronx, NY, USA
10:30-10:50 AM Presentations from Top 4 Posters
(4 @ 5 min each)
Chairs: Cyndya Shibao & Wolfgang Singer
10:50-11:25 AM Coffee Break
Dunes Foyer
11:25-12:30 PM Groundbreaking Research Plenary Lecture
The sacral autonomic outflow is sympathetic
Jean-François Brunet, M.D., Ph.D.
Paris, France
Chair: David S. Goldstein
Dunes I-III
12:30-2:30 PM Poster Session II
(box lunch)
2:30-4:00 PM Free Time

4:00-5:00 PM Trainee Round Tables

(mentor-mentee activities)
Pelican
5:00-6:00 PM Trainee Social
Pelican
6:00-6:45 PM Streeten Plenary Lecture
Lessons my patients taught me
Horacio Kaufmann, M.D.
New York, NY, USA
Chair: William P. Cheshire
Dunes I-III
Session 2: Cardiovascular Autonomic Regulation
Chairs: Amy Arnold, Mark Chapleau & Jens Jordan
Dunes I-III
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6:45-7:00 PM Best Basic Science Autonomic Research
2016 AAS-Lundbeck Research Fellowship Awardee
Exploring neuro-cardiovascular dysregulation in a mouse model of hypertrophic
cardiomyopathy
R.A. Larson, M.K. Kafa, M.Z. Cicha, R.M. Weiss, R. Sabharwal, M.W. Chapleau
Iowa City, IA, USA
7:00-7:15 PM Streeten Travel Fellowship Award
In-vivo measurement of brainstem and hypothalamic centers involved in blood
pressure regulation in humans: a high-resolution fMRI study with LBNP
N. Nazarenko, J. Manuel Sánchez, P. Stahl, K. Heusser, J. Jordan, J. Tank, F.
Beissner
Hannover, Germany
7:15-7:30 PM AAS-Lundbeck Travel Fellowship Award
QT interval lengthening and recovery following experimental hypoglycemia using
the hyperinsulinemic clamp procedure
B.M.W. Illigens, P.J. Marotta, J. White, I. Bonyhay, C.H. Gibbons, G.K. Adler, R.
Freeman
Boston, MA, USA
7:30-7:45 PM FMS/Penaz Wesseling Travel Fellowship Award
Muscle sympathetic nerve activity is not altered by experimental sleep restriction
in healthy humans
J.K. Limberg, W.W. Holbein, B.D. Johnson, N. Covassin, M.J. Joyner, V.K.
Somers
Rochester, MN, USA
7:45-8:00 PM FMS/Penaz Wesseling Travel Fellowship Award
Blood pressure response to experimental sleep restriction: effect of family history
of hypertension
N. Covassin, J. Bukartyk, A.D. Calvin, L. Ruzek, F. Soucek, E.K. St Louis, V.K.
Somers
Rochester, MN, USA
8:00-8:15 PM Differential effect of meal on alpha1-adrenoceptor function in the mesenteric
circulation in healthy humans
R. Meshulam, F. Zreik, O. Shibolet, G. Jacob
Tel-Aviv, Israel
8:15-8:30 PM Awards Presentations
Recognition of Fellows of the American Autonomic Society
Recognition of Longtime Supporters
Chairs: William P. Cheshire & Satish Raj

FRIDAY, NOVEMBER 3, 2017

8:00-8:30 AM Continental Breakfast
Pelican/Heron
8:30-9:15 AM MSA Plenary Lecture
Sleep disorders in multiple system atrophy
Pietro Cortelli, M.D.
Bologna, Italy
Chair: Horacio Kaufmann
Dunes I-III

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Session 3: Multiple System Atrophy and Other Synucleinopathies Symposium
Sponsored by The MSA Coalition and Theravance Biopharma
Chairs: Horacio Kaufmann & Wolfgang Singer
Dunes I-III
9:15-9:30 AM Intrathecal administration of autologous mesenchymal stem cells in multiple
system atrophy – a Phase I/II dose-escalation trial
W. Singer, A.B. Dietz, A.D. Zeller, T.L. Gehrking, A.M. Schmeichel, J.D.
Schmelzer, D.M. Sletten, J.A. Gehrking, E.A. Coon, P. Sandroni, E.E. Benarroch,
R.D. Fealey, J.Y. Matsumoto, J.H. Bower, J.E. Ahlskog, A. Hassan, A. McKeon,
B.T. Klassen, P.A. Low
Rochester, MN, USA
9:30-9:45 AM Profound myocardial norepinephrine deficiency in Parkinson’s disease
D.S. Goldstein, P. Sullivan, Y. Sharabi
Bethesda, MD, USA
9:45-10:00 AM Loss of bulbospinal inhibitory neurons in the ventrolateral medulla in multiple
system atrophy
A.M. Schmeichel, E.A. Coon, J.E. Parisi, P.A. Low, E.E. Benarroch
Rochester, MN, USA
10:00-10:15 AM Don Summers Memorial Multiple System Atrophy Travel Award
Preliminary results of the Global Multiple System Atrophy Registry (GLOMSAR):
an internet-based patient-reported registry
J.A. Palma, A. Porciuncula, F. Krismer, W. Meissner, H. Kaufmann, L. Norcliffe-
Kaufmann
New York, NY, USA
10:15-10:30 AM Alpha-synuclein deposition in a longitudinal study of Parkinson’s disease
C.H. Gibbons, N. Wang, J. Garcia, L. Shih, R. Freeman
Boston, MA, USA
10:30-10:45 AM Simultaneous assessment of alpha-synuclein deposition and catecholaminergic
innervation by immunofluorescence confocal microscopy in autonomic failure
R. Isonaka, P. Sullivan, C. Holmes, D.S. Goldstein
Bethesda, MD, USA
10:45-12:00 PM Genetics of Autonomic Disorders Symposium
Sponsored by Alnylam Pharmaceuticals, Dysautonomia Foundation and
PTC Therapeutics
Hereditary sensory and autonomic neuropathies (HSAN)
Lucy Norcliffe-Kaufmann, Ph.D.
New York, NY, USA
Autonomic dysfunction in familial amyloidosis
Alejandra Gonzalez-Duarte, M.D.
Mexico City, Mexico
The genetics of multiple system atrophy
Lucia Schottlaender, M.D.
London, England
Chairs: Roy Freeman & Jose-Alberto Palma
12:00-12:30 PM Box Lunch
Dunes I-III

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Session 4: Autonomic Contribution to Hypertension and Metabolism
Chairs: Qi Fu, Alfredo Gamboa & Jens Tank
Dunes I-III
12:30-12:45 PM Peripheral chemoreceptor modulation and the efficacy of baroreflex activation by
electrical carotid sinus stimulation in patients with therapy resistant arterial
hypertension
K. Heusser, A. Thöne, A. Lipp, J. Menne, J. Beige, H. Reuter, F. Hoffmann, M.
Halbach, S. Eckert, M. Wallbach, M. Koziolek, H. Haarmann, M. Joyner, J.F.
Paton, A. Diedrich, H. Haller, J. Jordan, J. Tank
Hannover, Germany
12:45-1:00 PM Use of Mayer wave amplitudes to demonstrate aberrant cardiovascular autonomic
control following concussion
M.F. LaFountaine, A.J. Testa, J.P. Weir
South Orange, NJ, USA
1:00-1:15 PM Angiotensin-(1-7) does not acutely lower blood pressure in patients with essential
hypertension
A.C. Arnold, J.E. Celedonio, S.Y. Paranjape, I. Biaggioni, A. Gamboa
Hershey, PA, USA
1:15-1:30 PM AAS-Lundbeck Travel Fellowship Award
The use of lidocaine lubricant in bowel management practices does not improve
autonomic dysreflexia in spinal cord injury: a randomized clinical trial
V.E.M. Lucci, M.S. McGrath, R. Willms, V.E. Claydon
Burnaby, BC, Canada
1:30-1:45 PM African Americans with CD36 partial deficiency have enhanced cardiovascular
parasympathetic tone
S.E. Mehr, J.E. Celedonio, A. Diedrich, N.N. Abumrad, C.R. Flynn, N.A. Abumrad,
C.A. Shibao
Nashville, TN, USA
1:45-2:00 PM Autonomic and metabolic dysregulation in a novel mouse model of metabolic
syndrome
R. Sabharwal, L. Yang, M.W. Chapleau
Iowa City, IA, USA
2:00-7:00 PM Free Time
2:30-4:30 PM AAS Board Meeting
Ibis
4:30-5:30 PM CAR Editorial Board Meeting
Ibis
5:30-6:30 PM AAS Committee Meetings
Pelican/Heron
7:00-10:00 PM Presidential Dinner
Pool Deck

SATURDAY, NOVEMBER 4, 2017

8:00-8:30 AM Continental Breakfast
Pelican/Heron

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8:30-9:15 AM POTS Symposium
Pediatric POTS: the blind men, the elephant, and the drone
Jeffrey R. Boris, M.D.
Philadelphia, PA, USA
Chair: Satish Raj
Dunes I-III
Session 5: Postural Tachycardia Syndrome and Autonomic Neuropathy Symposium
Sponsored by Dysautonomia International
Chairs: Amanda Peltier & Satish Raj
Dunes I-III
9:15-9:30 AM AAS-Lundbeck Travel Fellowship Award
Nitric oxide function in POTS during high and low sodium diets
J.E. Celedonio, V.C. Nwazue, S.Y. Paranjape, E.M. Garland, L.E. Okamoto, C.A.
Shibao, I. Biaggioni, S.R. Raj, A. Gamboa
Nashville, TN, USA
9:30-9:45 AM Postural tachycardia in hypermobile Ehlers-Danlos syndrome: symptom burden
and healthcare utilization
M.G. Miglis, B. Schultz, S. Jaradeh, S. Muppidi
Palo Alto, CA, USA
9:45-10:00 AM Microneurographic evidence of primary hyperadrenergic POTS
L.E. Okamoto, E.M. Garland, K. Sato, L. Diedrich, R. Furlan, G. Jacob, D.
Robertson, I. Biaggioni, A. Diedrich
Nashville, TN, USA
10:00-10:15 AM A double blind-placebo controlled trial of IVIG in the treatment of AAG: results,
implications and lessons learned
C.H. Gibbons, S. Rajan, J. Garcia, R. Freeman
Boston, MA, USA
10:15-10:45 AM Coffee Break
Dunes Foyer
Session 6: Pediatric Autonomic Disorders
Chairs: Gisela Chelimsky & Julian Stewart
Dunes I-III
10:45-11:00 AM Expanding the genetic and phenotypic spectrum of hereditary sensory and
autonomic neuropathies: role of whole exome sequencing
J.A. Palma, L. Norcliffe-Kaufmann, S.A. Slaugenhaupt, H. Kaufmann
New York, NY, USA
11:00-11:15 AM Percutaneous electrical nerve field stimulation (PENFS) increases vagal tone in
adolescent functional abdominal pain disorders (aFAPDs)
K. Kovacic, A. Miranda, T. Chelimsky, L. Zhang, P. Simpson, G. Chelimsky
Milwaukee, WI, USA
11:15-11:30 AM Mechanisms of vasovagal syncope in the young: reduced systemic vascular
resistance versus reduced cardiac output
M.S. Medow, R. Sutton, P. Visintainez, D.L. Jardine, W. Wieling, J.M. Stewart
Valhalla, NY, USA
11:30-11:45 AM Mechanisms of vasovagal syncope in the young
J.M. Stewart, M.S. Medow, R. Sutton, P. Visintainer, D.L. Jardine, W. Wieling
Valhalla, NY, USA

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11:45-12:00 PM Baro-receptor sensitivity (BRS) in children and young adults: comparing normal
controls to POTS (postural orthostatic tachycardia syndrome) and
neurocardiogenic syncope patients
M. Alnoor, H. Varner, I. Butler, M. Numan
Houston, TX, USA
12:00-12:30 PM AAS Business Meeting
Dunes I-III
12:30-12:45 PM CLOSING REMARKS
William P. Cheshire, M.D.
President, American Autonomic Society
Dunes I-III

Afternoon Patient Seminar: Updates from the 2017 AAS Meeting

2:00-4:00 PM Organized by Dysautonomia International
Dunes I-III
(separate registration required)

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POSTER SESSION I
WEDNESDAY, NOVEMBER 1, 2017
6:30-9:00 PM
Dunes IV-V

Trainee Poster Competition* Judges: AAS Board Members

Autonomic Failure: PAF, MSA, Parkinson’s Disease

Poster #1* The effect of exercise on heart rate variability during sleep in Parkinson’s
disease
A.A. Memon, R.A. Memon, K. Wood, A. Joop, J. Pilkington, M. Bamman, S. Pati,
A.W. Amara
Birmingham, AL, USA
Poster #2 Depression in multiple system atrophy: association with disease progression and
autonomic symptoms
J.M. Martinez, J.A. Palma, L. Norcliffe-Kaufmann, H. Kaufmann
New York, NY, USA
Poster #3 Psychosis in multiple system atrophy
J.A. Palma, C.R. de Camargo, J. Martinez, L. Norcliffe-Kaufmann, H. Kaufmann
New York, NY, USA
Poster #4 Cold-induced sweat: an uncommon presentation of pure autonomic failure
E. Villareal-Vitorica, C.R. de Camargo, J.A. Palma, L. Norcliffe-Kaufmann, H.
Kaufmann
New York, NY, USA
Poster #5 Recurrent episodes of loss of consciousness; a case of seronegative
autoimmune autonomic ganglionopathy with features of postural orthostatic
tachycardia syndrome treated with plasmapheresis: a prospective case study
R.A. Khan, M. Mazhar, C.E. Kaufman
Oklahoma City, OK, USA
Autonomic Regulation: Basic Science & Animal Studies
Poster #6 2016 AAS-Lundbeck Research Fellowship Awardee
Activation of hypothalamic oxytocin neurons restores oxytocin release to
parasympathetic cardiac vagal neurons of the brainstem in left ventricular
hypertrophy induced heart failure
J. Dyavanapalli, D. Mendelowitz
Washington, DC, USA
Cardiac Autonomic Innervation: Humans
Poster #7 Differentiating positive and negative blood pressure variations in the computation
of baroreflex sensitivity in amyotrophic lateral sclerosis
B. De Maria, A. Porta, G. Galizia, R. Sideri, K. Marinou, G. Mora, L. Dalla
Vecchia
Milan, Italy
Poster #8 Centripetal degeneration of cardiac sympathetic nerves in Lewy body diseases
D.S. Goldstein, P. Sullivan, Y. Sharabi
Bethesda, MD, USA

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Poster #9* Patients with a history of mild traumatic brain injury have impaired autonomic
responses to unpleasant odorous stimuli
M. Liu, F. Ammon, J. Markus, R. Wang, K.M. Hösl, T. Hummel, M.J. Hilz
Erlangen, Germany
Poster #10 Blood pressure variability accurately quantifies the evolution of autonomic
cardiovascular control in acute spinal cord injury
V.E.M. Lucci, J.A. Inskip, O.A. Sandberg, S.S. Bajaj, I. Ruiz-Romero, M.S.
McGrath, B.K. Kwon, V.E. Claydon
Burnaby, BC, Canada
Cardiorespiratory Coupling, Dysautonomia in Schizophrenia
Poster #11 Paced breathing enhancements of cardiorespiratory coupling: a potential therapy
to schizophrenia dysautonomia
B. Goubran, L. Firulescu, A. Dumenigo, R. Aguirre, R.W. May, F.D. Fincham,
J.D. Oms, M.A. Sanchez-Gonzalez
South Miami, FL, USA
Cardiovascular Disease, Obesity & Aging: Human Studies
Poster #12* Autonomic symptoms in pre-bariatric surgery patients and at 3 months post
surgery
V.M. Ponnusamy, A.P. Owens, C.J. Mathias, H. Chahal, S. Purkayastha, V.
Iodice
London, UK
Cerebral Blood Flow Regulation
Poster #13 The relationship between cardiovascular and cerebrovascular responses to
head-up tilt in patients with orthostatic intolerance
T.S. Ahern, K.M. Dickson, K.A. Lichtenstein, M.E. Parker, A. McGlamery, A.
Vaene, A. Kim, A. Cabral, M.A. Kalafut, J.R. Criado
La Jolla, CA, USA
Poster #14* Position-dependent changes of blood flow in carotid arteries assessed by
camera-based photoplethysmography
O.V. Mamontov, T.V. Krasnikova, M.A. Volynsky, E.V. Shlyakhto, A.A. Kamshilin
St. Petersburg, Russia
Poster #15 Differential perfusion between the cerebral hemispheres depicted by near-infra
red spectroscopy during head up tilt table test
H. Elfadeel, H. Varner, J. Lankford, I. Butler, M. Numan
Houston, TX, USA
Diabetic, Autoimmune & Other Autonomic Neuropathies
Poster #16 Toenail changes in autonomic neuropathy
G.A. Cook, Y. Ma
Portsmouth, VA, USA
Poster #17 A case of a patient with tonic pupil and hypohydrosis
H.N. Jeong, S.W. Kim
Seoul, South Korea
Poster #18 Clarification of hypoglycemic symptoms in patients with autonomic dysfunction
J.L. Gilden, B. Osmani, E. Ariano, E. Abousaad, A. Al-Khazaali, M. Siddiqui, A.
Moid, B.G. Theckedath
North Chicago, IL, USA
Gastrointestinal & Urogenital Systems, IBS, Cystitis

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Poster #19* Effect of the autonomic nervous system on splanchnic circulation before and
after meals
F. Zreik, R. Meshulam, O. Shibolet, G. Jacob
Tel Aviv, Israel
Poster #20 Gastric myoelectrical and neurohormone changes associated with nausea during
tilt-induced syncope
G.L. Heyer, L.H. Boles, R.A. Harvey, M.J. Cismowski
Columbus, OH, USA
Poster #21 Inhibition of somatostatin release from enteric neurons of the guinea pig tenia
coli by neurohumoral peptides of the vasoactive intestinal peptide (VIP)-secretin
family
J.R. Grider, K.S. Murthy, G.M. Makhlouf
Richmond, VA, USA
Poster #22 Impairment of mitochondrial bioenergetics in functional disorders does not
improve with clinical amelioration
J. de los Santos, E. Awe, D. Johannes, D. Bierer, L. Zhong, S. Komas, B.
Kalyanaraman, J. Banda, G. Chelimsky, T. Chelimsky
Milwaukee, WI, USA
Genetic Autonomic Disorders
Poster #23* Arterial stiffness: a possible link between orthostatic intolerance and Ehlers-
Danlos syndromes
A.J. Miller, J. Schubart, R. Bascom, C. Francomano, S. Mills, E. Schaefer, T.
Sheehan, A. Dimmock, L.I. Sinoway
Hershey, PA, USA
Poster #24* Incidence and prevalence of cancer and neoplasia in familial dysautonomia
C.R. de Carmargo, J.A. Palma, L. Norcliffe-Kaufmann, H. Kaufmann
New York, NY, USA
Microneurography & Cardiovascular Reflexes in Humans
Poster #25 Muscle sympathetic nerve activity peaks in the first trimester in healthy
pregnancy: a longitudinal case study
S.L. Hissen, K. El Sayed, V.G. Macefield, R. Brown, C.E. Taylor
Sydney, NSW, Australia
Poster #26* Effect of chronic anxiety on sympathetic vasoconstrictor and cardiac
responsiveness in humans
S.W. Holwerda, R.E. Luehrs, L.E. DuBose, N.A. Wooldridge, J.G. Fiedorowicz,
F.M. Abboud, G.L. Pierce
Iowa City, IA, USA
Novel Therapies & Clinical Trials
Poster #27* Can intermittent calf compression improve orthostatic tolerance?
B.C.D. Hockin, L.J. Rietchel, V.E. Claydon
Burnaby, BC, Canada
Poster #28 Intranasal dexmedetomidine for adrenergic crisis in familial dysautonomia
C.L. Spalink, E. Barnes, J.A. Palma, L. Norcliffe-Kaufmann, H. Kaufmann
New York, NY, USA
Poster #29* The effect of dipeptidyl peptidase IV inhibition on norepinephrine release in the
setting of neuropeptide Y infusion
S.A. Hubers, J.R. Wilson, C.A. Shibao, N.J. Brown
Nashville, TN, USA

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Poster #30 Stimulation of the dorsal root ganglion (DRG) for medicine refractory chronic
neuropathic pain: is there sympathetic involvement?
Y.B. Sverrisdóttir, J. Fitzgerald, A. Kent, J. Kramer, A.L. Green
Oxford, UK
Orthostatic Hypotension and Syncope
Poster #31* Orthostatic heart rate-blood pressure relationship identifies neurogenic
orthostatic hypotension
A. Velasco, L.E. Okamoto, E.M. Garland, Y. Chang, I. Biaggioni
Birmingham, AL, USA
Poster #32* Validity and reliability of orthostatic and non-orthostatic symptoms scores derived
from the Orthostatic Discriminant and Severity Scale – a new instrument to
discriminate orthostatic from non-orthostatic symptoms
J. Baker, J. Paturel, K. Kimpinski
London, ON, Canada
Poster #33* Recent syncopal burden, but not prior syncope burden, predicts quality of life
J. Ng, R.S. Sheldon, D. Ritchie, V. Raj, S.R. Raj
Calgary, AB, Canada
Poster #34* Quality of life improves in vasovagal syncope patients regardless of fainting in
follow-up: role of syncope expert?
J. Ng, R.S. Sheldon, C. Maxey, D. Ritchie, S.R. Raj
Calgary, AB, Canada
Poster #35* Initial cardiovascular response to head-up tilt (HUT) in vasovagal syncope (VVS)
S. Balegh, J. Benoît, B. Ditto, R. Schondorf
Montréal, QC, Canada
Postural Orthostatic Tachycardia Syndrome (POTS)
Poster #36 Symptom relief from median arcuate ligament syndrome corrective surgery in
patients with postural orthostatic tachycardia syndrome and median arcuate
ligament syndrome
A. Abouelnasr, S. Alam, Z. Rehman, H. Mistry, K. Munez, R. Abu-Jajeh, M.A.
Nasri, M. Khan, A. Chandralekha, A. Suleman, R. Overberg
McKinney, TX, USA
Poster #37 Effectiveness of droxidopa in children with postural orthostatic tachycardia
syndrome
B. Kakavand, K. Pires
Orlando, FL, USA
Poster #38 Prospective screening for intracranial aneurysms in patients with Ehlers-Danlos
syndrome presenting with POTS
D.S. Saperstein
Phoenix, AZ, USA
Poster #39* Employment and economic impacts of postural tachycardia syndrome: insights
from a cross-sectional community-based survey
K. Bourne, J. Ng, L. Stiles, B.H. Shaw, E.A. Green, C.A. Shibao, L.E. Okamoto,
E.M. Garland, A. Gamboa, A. Peltier, A. Diedrich, I. Biaggioni, D. Robertson,
S.R. Raj
Calgary, AB, Canada

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Poster #40 Educational and social impacts of postural tachycardia syndrome: insights from a
cross-sectional community-based survey
L. Stiles, J. Ng, B.H. Shaw, E.A. Green, C.A. Shibao, L.E. Okamoto, E.M.
Garland, A. Gamboa, A. Peltier, A. Diedrich, I. Biaggioni, D. Robertson, S.R. Raj
East Moriches, NY, USA
Poster #41* Coagulopathies in postural orthostatic tachycardia syndrome
K. Munez, H. Mistry, N. Joy, S. Alam, M.A. Nasri, W. Almardini, Z. Rehman, E.
Algabre, A. Suleman
McKinney, TX, USA
Poster #42 Effects of Ivabradine on autonomic parameters in postural orthostatic
tachycardia syndrome (POTS) patients
M.A. Nasri, S. Alam, K. Kommera, H. Mistry, K. Munez, N. Joy, E. Algabre, R.
Iqbal, R.D. Dada, A. Suleman
McKinney, TX, USA
Poster #43 Pseudobulbar affect in postural tachycardia syndrome
R.K. Khurana
Baltimore, MD, USA
Cognitive Dysfunction in Autonomic Disorders
Poster #44* Autonomic contributions to psychological symptomatology in clinical disorders of
autonomic hyperarousal
A.P. Owens, D.A. Low, V. Iodice, H.D. Critchley, C.J. Mathias
London, UK
Pupillary Autonomic Modulation
Poster #45* Disease duration and severity correlate with reduced pupillary modulation in
patients with relapsing-remitting multiple sclerosis
M.J. Hilz, R. Wang, S. Roy, M. Liu, C. de Rojas Leal, K. Hösl, D.H. Lee, R.A.
Linker
Erlangen, Germany
Sleep Dysfunction in Autonomic Disorders
Poster #46* Sleep and autonomic impairment in Ehlers-Danlos syndrome: a case series
B. Schultz, C. Guilleminault, S. Jaradeh, M.G. Miglis
Palo Alto, CA, USA
Sympathovagal Balance, Spectral Analysis
Poster #47* The equivalency of non-invasive measures of vagal baroreflex sensitivity and
their relationship to orthostatic cardiac responses
M.G. Lloyd, M. Koehle, R.J. Drapala, V.E. Claydon
Burnaby, BC, Canada
Poster #48* Fingolimod discontinuation restores cardiovagal gain in patients with relapsing-
remitting multiple sclerosis
S. Roy, R. Wang, M. Liu, C. de Rojas Leal, K. Hösl, D.H. Lee, R.A. Linker, M.J.
Hilz
Erlangen, Germany
Poster #49* Effects of cigarette smoking on blood pressure and heart rate variability in
habitual smokers
E.V. Saperova, D.A. Dimitriev
Cheboksary, Russia
The Science of Clinical Practice

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Poster #50 Autonomic lifestyles and Fitbit pitfalls: how personal biosensors are changing
medical practice
W.P. Cheshire
Jacksonville, FL, USA
POSTER SESSION II
THURSDAY, NOVEMBER 2, 2017
12:30-2:30 PM
Dunes IV-V

Autonomic Dysfunction in Carcinomas

Poster #51 Role of heart rate variability and pulse wave analysis to quantify subclinical
autonomic dysfunctions in cancer patients
E. Khandelwal, S. Tripathi
Raipur, India
Autonomic Failure: PAF, MSA, Parkinson’s Disease
Poster #52 Addressing orthostatic hypotension in Parkinson disease patients in a neurology
resident continuity clinic
E.P. Golden, T. Le, L.S. Brown, P. Khemani
Dallas, TX, USA
Poster #53 Low CSF DOPA and DOPAC predict Parkinson’s disease
D.S. Goldstein, C. Holmes, G.J. Lopez, T. Wu, Y. Sharabi
Bethesda, MD, USA
Poster #54 Smoking and alcohol use influence age of onset in multiple system atrophy
L.M. Jones, J.E. Ahlskog, J.H. Bower, J.Y. Matsumoto, P. Sandroni, E.E.
Benarroch, M. Suarez, P.A. Low, W. Singer, E.A. Coon
Rochester, MN, USA
Poster #55 Association between complexity analysis of the systolic arterial pressure and
heart rate variability and rate of disease progression in patients with amyotrophic
lateral sclerosis
B. De Maria, G. Mora, K. Marinou, R. Sideri, R. Furlan, F. Barbic, A. Porta, L.
Dalla Vecchia
Milan, Italy
Poster #56 Vagal baroreflex sensitivity reflects the progression of Parkinson’s disease
K.J. Park, H. Jeong, E.B. Cho, T. Yang, S. Jung, J.Y. Chang
Jinju, The Republic of Korea
Autonomic Testing
Poster #57 Electrochemical skin conductance and the relationship to autonomic structure
and function in diabetes
C.H. Gibbons, J. Garcia, M. Casasola, R. Freeman
Boston, MA, USA
Poster #58 Does physiological volume status affect Q-Sweat volume?
J.A. Gehrking, D.M. Sletten, T.L. Gehrking, K. Minota, W. Singer, P.A. Low
Rochester, MN, USA
Diabetic, Autoimmune & Other Autonomic Neuropathies
Poster #59 Small fiber neuropathy associated with IgG monoclonal gammopathy
H.N. Jeong, S.W. Kim
Seoul, South Korea

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Poster #60 Positive GAD-65 antibodies in patients with autonomic dysfunction
L. Vlahovic, L. Kipp, L. Nguyen, J. Dunn, S. Jaradeh
Stanford, CA, USA
Poster #61 A randomized, blinded, parallel group lifestyle intervention study improves the
expiration:inspiration ratio in subjects with diabetic neuropathy
L. Zilliox, M. Morado, P. Kumar, K. Fleishmann, J.W. Russell
Baltimore, MD, USA
Epidemiology of Autonomic Disorders
Poster #62 Prevalence and incidence rates of autonomic disorders among U.S. Military
Healthcare System beneficiaries never diagnosed with diabetes
G.A. Cook, C.A. Shibley, E. Williams IV
Portsmouth, VA, USA
Exercise, Temperature Regulation & Hypoxia
Poster #63 PEARL™: Parkinson Exercise Autonomic Response Level — a bedside rating
scale to estimate exercise capabilities in Parkinson diseases
B. Weinstock
Brooklyn, NY, USA
Poster #64 Can resting heart rate influence heart rate recovery after submaximal exercise
test?
G.L. Garcia, K.E. Fontana, C.J.G. Cruz, E.M.K.V.K. Soares, L.G.G. Porto, L.F.
Junqueira Jr., G.E. Molina
Brasília, Brazil
Genetic Autonomic Disorders
Poster #65 Autonomic neuropathy in Wolfram syndrome
W.P. Cheshire, C.E. D’Souza, R.J. Uitti
Jacksonville, FL, USA
Poster #66 Allgrove syndrome (triple A syndrome): two cases and the fourth “A”
A.B. Murphy, J.A. Palma, H. Kaufmann
New York, NY, USA
Microneurography & Cardiovascular Reflexes in Humans
Poster #67 Role of corin in blood pressure regulation during pregnancy in humans
Q. Fu, S. Park, J.K. Yoo, M. Hieda, Y. Okada, S.S. Jarvis, A.S. Stickford, S.A.
Best, B.D. Levine
Dallas, TX, USA
Poster #68 Interindividual differences in sympathetic baroreflex sensitivity and vascular
transduction
S.L. Hissen, V.G. Macefield, R. Brown, C.E. Taylor
Sydney, NSW, Australia
Poster #69 The effect of 6 weeks of high-intense training on MSNA levels in hypertensive
males
T.S. Ehlers, T.P. Gunnarsson, M. Fiorenza, M.P. Nyberg, J. Bangsbo, Y.B.
Sverrisdóttir
Copenhagen, Denmark
Music and the Autonomic Nervous System
Poster #70 Effect of tempo and harmony on the autonomic nervous system
K.R. Chémali, K. McNeeley, D. Russell
Norfolk, VA, USA
Neuroimaging in Brain & Heart

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Poster #71 Comparison of 3T and 7T MRI imaging of the periaqueductal gray region (PAG)
C. Ustine, L. Zhong, L.T. Muftler, S.J. Li, G. Chen, E. Awe, C. Dean-Bernhoft, S.
Rand, G. Chelimsky, T. Chelimsky
Milwaukee, WI, USA
Poster #72 Correlation of autonomic dysfunction with the atrophy of central autonomic brain
areas in SCA patients
D. Tamuli, M. Kaur, S.S. Kumaran, A.K. Jaryal, A.K. Srivastava, K.K. Deepak
New Delhi, India
Poster #73 Neuroimaging biomarkers of putamen and cardiac catecholamine deficiency
identify early Parkinson’s disease
D.S. Goldstein, C. Holmes, G.J. Lopez, R. Isonaka, R.T. Vontell, T. Wu, Y.
Sharabi
Bethesda, MD, USA
Orthostatic Hypotension and Syncope
Poster #74 Syncopedia: filling the physician’s knowledge gap on transient loss of
consciousness
J.S.Y. de Jong, W. Wieling, F.J. de Lange, on behalf of the Syncopedia Editorial
Board
Amsterdam, The Netherlands
Poster #75 Topical diagnostics of arterial baroreflex dysfunction in patients with orthostatic
hypotension.
O.V. Mamontov, A.V. Kozlenoc, E.V. Shlyakhto
St. Petersburg, Russia
Poster #76 Implications of initial orthostatic hypotension seen during tilt table testing
A. Barboi, V. Patel, S. Pocica, S. Moffat, M. Plonka
Evanston, IL, USA
Poster #77 Role of potential confounders in affecting hospital admission because of syncope
F. Barbic, L. Canziani, R. Menè, M. Minonzio, A.G. Bottaccioli, D. Alhon-Shiffer,
F. Dipaola, E. Brunetta, M. Solbiati, L. Furlan, V. Bozzano, A. Galli, C. Conca, G.
Costantino, R.S. Sheldon, R. Furlan
Rozzano, Italy
Poster #78 Is hospital admission useful for syncope patients? Preliminary results of a
propensity analysis
F. Dipaola, E. Pivetta, G. Costantino, J. Quinn, A. Ungar, M. Solbiati, F. Barbic,
M. Gatti, R. Furlan
Milan, Italy
Poster #79 Neurogenic orthostatic hypotension burden of illness patient and caregiver
survey: impact of symptoms
D.O. Claassen, C.H. Adler, C.H. Gibbons, L.A. Hewitt
Nashville, TN, USA
Poster #80 Orthostatic responses to lunar and Martian gravity loads
U. Limper, P. Beck, P. Gauger, L. Beck, J. Tank, J. Jordan
Cologne, Germany
Migraine & Sleep
Poster #81 Sleep induction following cranial nerve modulation in migraine subjects
R.M. Harper, M.R. White, R.K. Harper, D. Snodgrass, F. Yan-Go, J. Jen, A.
Taghizadeh, E.K. Sauerland
Los Angeles, CA, USA
Pediatric Autonomic Disorders

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Poster #82 Vagal modulation in pediatric Functional Pain and Autonomic Disorders (pFPAD)
improves as disability improves: preliminary report
G. Chelimsky, L. Zhong, E. Awe, D. Johannes, K. Kovacic, T. Chelimsky
Milwaukee, WI, USA
Poster #83 Afferent baroreflex failure in children and young adults
J.A. Palma, L. Norcliffe-Kaufmann, H. Kaufmann
New York, NY, USA
Poster #84 How long to tilt in pediatrics? 10 minutes is not enough!
M. Witzlib, T. Chelimsky, G. Chelimsky
Children’s Hospital of Wisconsin and Medical College of Wisconsin, Milwaukee,
WI, USA
Postural Orthostatic Tachycardia Syndrome (POTS)
Poster #85 Utilization of medications to reduce the symptoms in pediatric patients with
postural orthostatic tachycardia syndrome
J.R. Boris, T. Bernadzikowski
Philadelphia, PA, USA
Poster #86 The diagnostic journey and costs in postural tachycardia syndrome: insights from
a cross-sectional community-based patient survey.
L. Stiles, B.H. Shaw, E.A. Green, C.A. Shibao, L.E. Okamoto, E.M. Garland, A.
Gamboa, A. Peltier, A. Diedrich, I. Biaggioni, D. Robertson, S.R. Raj
East Moriches, NY, USA
Poster #87 Case report of May-Thurner syndrome surgery in postural orthostatic tachycardia
syndrome
K. Munez, H. Mistry, E. Algabre, N. Joy, M.A. Nasri, S. Alam, R.D. Dada, A.
Suleman
McKinney, TX, USA
Poster #88 POTS after an acute viral infection: role of reversed A:G ratio in clinical diagnosis
P. Kumar, S. Gupta, S. Raghavan
New Delhi, India
Poster #89 Postural orthostatic tachycardia syndrome (POTS) - its impact on school and
work participation
T.S. Ahern
La Jolla, CA, USA
Poster #90 Irritable heart syndrome without orthostatic tachycardia
H.J. Snapper
Atlanta, GA, USA
Poster #91 Droxidopa management in postural orthostatic tachycardia syndrome (POTS)
patients
N. Joy, E. Algabre, H. Mistry, K. Munez, M.A. Nasri, S. Alam, R. Jajunda, K.
Kommera, Z. Rehman, A. Suleman
McKinney, TX, USA
Poster #92 Median arcuate ligament surgery in postural orthostatic tachycardia syndrome
(POTS) – is post operative celiac artery velocity (POCAV) a success marker?
R.D. Dada, M.A. Nasri, H. Mistry, K. Kommera, N. Joy, K. Munez, S. Alam, E.
Algabre, R. Iqbal, A. Suleman
McKinney, TX, USA

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Poster #93 Autonomic parameters in postural orthostatic tachycardia syndrome patients
before and after median arcuate ligament syndrome surgery
S. Alam, K. Kommera, H. Mistry, K. Munez, E. Algabre, M.A. Nasri, N. Joy, R.D.
Dada, A. Suleman
McKinney, TX, USA
Poster #94 Vitamin D deficiency study in postural orthostatic tachycardia syndrome (POTS)
patients
K. Kommera, Z. Rehman, C. Ashanagri, A. Suleman
McKinney, TX, USA
Serious Mental Illness and Autonomic Dysfunction
Poster #95 Time course of improvement in autonomic function and attention in acute
psychosis: a case report
R.R. Aguirre, M. Zirio Mustafa, A. Dumenigo, S. Schulz, A. Voss, R. Dumenigo,
M.A. Sanchez-Gonzalez
South Miami, FL, USA
Supine Hypertension and Neurogenic Orthostatic Hypotension
Poster #96 Assessment of autonomic function during ictal and interictal period of migraine
S. Bansal, A.K. Srivastava
New Delhi, India
Sympathovagal Balance, Spectral Analysis
Poster #97 Correlation of autonomic and cognitive impairment in patients with a history of
traumatic brain injury
M.J. Hilz, K. Hösl, C. de Rojas Leal, S. Roy, M. Liu, R. Wang
Erlangen, Germany
Poster #98 Cardiovascular autonomic control during paced-respiration hypnosis
E. Brunetta, M. Minonzio, F. Barbic, D. Lopane, C. Poggio, F. Dipaola, C.
Margotti, P.R. Tomasin, R. Furlan
Rozzano, Italy
Poster #99 Optical imaging of baseline and stimulus-induced changes in facial perfusion
M. Cortez, N. Rea, J. Theriot, K.C. Brennan
Salt Lake City, UT, USA
Poster #100 Sympathetic cardiovascular modulation increases after three years of Fingolimod
therapy
R. Wang, S. Roy, M. Liu, C. de Rojas Leal, K. Hösl, D.H. Lee, R.A. Linker, M.J.
Hilz
Erlangen, Germany

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ACCME Accreditation Statement:
This activity has been planned and implemented in accordance with the accreditation requirements
and policies of the Accreditation Council for Continuing Medical Education through the joint
providership of The Medical College of Wisconsin and American Autonomic Society. The Medical
College of Wisconsin is accredited by the ACCME to provide continuing medical education for
physicians.

AMA Credit Designation Statement:

The Medical College of Wisconsin designates this for a maximum of 14.75 AMA PRA Category 1
Credit(s)™. Physicians should claim only the credit commensurate with the extent of their
participation in the activity.

Hours of Participation for Allied Health Care Professionals:

The Medical College of Wisconsin designates this activity for up to 14.75 hours of participation for
continuing education for allied health professionals.

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The American Autonomic Society would like to thank the following
for their support of this meeting:

PLATINUM SPONSOR

SYMPOSIA SPONSORS

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TRAVEL AWARD SPONSORS

OTHER SPONSORS

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