Worksheet 1 - Human Genetics

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Name: Lei Zaira A.

Biendima Course Year and Section: BS BIOLOGY4B

Worksheet #1
Introduction to Immunology

A. Immune system Vocabulary. Use the words from the word bank to answer A1 and A2.

A.1. Circle the immune system vocabulary words from the word bank. They could be arranged
vertically, horizontally, diagonally, and backward.
A.2. Instructions: Fill in the blanks with the words from the word bank.

1. The immune system protects your body from sickness and germs.
2. Leukocytes are white blood cells that seek out and destroy organisms or substances that can
cause disease.
3. Lymph nodes are glands that work like filters to remove germs. They’re found in your neck,
armpit, and other areas.
4. Cells that chew up invading germs are called phagocytes.
5. Lymphocytes are the cells that recognize invaders like germs.
6. Leukocytes travel through the body via lymphatic vessels.
7. A foreign substance that invades your body is called an antigen.
8. When your body detects an antigen, antibodies are made and lock onto it. Once an antigen is
recognized, your immune system can remember it the next time and protect you from getting
sick again.
9. Humans are born with innate immunity.
10. Hand washing is one of the best ways to avoid infections and help keep your immune system
healthy.
11. Immunodeficiencies occur when a part of the immune system is not present or is not
working properly.
12. When the immune system attacks healthy organs and tissues, it’s called an autoimmune
disorder.
13. An allergic reaction occurs when the immune system overreacts to exposure to antigens in
the environment.
14. Acquired immunodeficiencies can develop as a result of burns, malnutrition, or other medical
problems; or if a person takes certain medicines or has a disease.
15. An abnormal overgrowth of leukocytes results in leukemia, a form of cancer.
B. Pretest

Matching. Match column A with column B. Write the letter of your answer before the number.
Column A Column B
J 1. Natural immunity, the first line of defense
against foreign organisms and substances.
E 2. Skin and mucosal linings of respiratory and
gastrointestinal tract
a. Antigen
F 3. Tears and saliva contain this enzyme that kills
F
bacteria by breaking the peptidoglycan layer
F of cell walls. b. Adaptive immunity
G 4. Host cell engulfs and destroys the foreign
G organism. c. Cytokines
F
H 5. White cells in the blood; nucleated cells
G originated from bone marrow. d. Complement
6. A group of plasma and cell surface proteins
FD
G that fights invading organisms. e. Physical barriers
FC 7. Secretory proteins produced by lymphocytes f. Lysozyme
and monocytes in response to microbial
G
F antigens; help cell-to-cell communication, g. Phagocytosis
inflammatory reactions, immune response
G
F reactions. h. Neutrophils
I 8. Response to antigen
G
B 9. Second line of defense; develops memory for i. Antibody
subsequent exposure to the previously
G encountered organisms. j. Innate Immunity
AFF 10. Foreign microbial and non-microbial
substances

GG
F
Multiple Choice. Select the best answer by writing the letter before the number.

C 11. A __________________ is a disease-causing organism.


a. Bacteria G
b. Virus
c. Pathogen
F d. Antigen
D 12. Molecules that stimulate an immune response
a. Bacteria
G b. Virus
c. Pathogen
d. Antigen
A 13. White blood cells that produce antibodies and aid in immune response memory are called... a.
B cells

F
b. T cells
c. Monocyte
d. Granulocyte
B 14. White blood cells specialized to assist B cells are called...
a. B cells
b. T cells
c. Monocyte
F d. Granulocyte
C 15. Nonliving particle containing protein and DNA/RNA that can infect a living cell a. Bacteria
b. Microorganism
G c. Virus
d. Fungus
D
F 16. Which of the following is an example of the first line of defense?
a. Neutrophil
b. B cell
G c. Inflammation
F d. Normal microbiota
A 17. Which of the following is an example of the second line of defense?
a. Inflammation
G b. Skin
c. T helper cells
F d. Antibodies
D 18. Which of the following is an example of the third line of defense?
a. Lysozyme
G b. B cell
c. Neutrophil
F d. Antibodies
19. Compare and contrast innate and adaptive immunity.
G Innate immunity is the body’s first line of defense against pathogens. It is general and non-
specific, which means it does not differentiate between types of pathogens. Adaptive immunity
is a type of immunity that is built up as we are exposed to diseases or get vaccinated. Both
innate and adaptive immunity are two types of immunities that protect the body from harmful
pathogens and toxins.

20. What are the two primary lymphoid organs and what role do each play?
The two primary lymphoid organs include the bone marrow and thymus. Bone marrow
forms a specialized stem cell connective tissue that fills the cavities of most bones.
Thymus makes and trains special white blood cells called T-cells.

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