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    Ranitidine is a histamine H2 receptor antagonist used to inhibit gastric acid secretion and reduce gastric volume. It works by inhibiting histamine action at H2 receptors in gastric parietal cells. Common side effects include headache, abdominal pain, agitation, and hair loss. Nurses should assess for abdominal pain or distress and monitor for potential side effects. Vancomycin is a glycopeptide antibiotic that inhibits bacterial cell wall synthesis. It works by binding to terminal amino acids during cell wall synthesis, inhibiting transpeptidation and preventing further cell wall formation. Potential adverse effects include nephrotoxicity, ototoxicity, and red man syndrome. Nurses should monitor renal function, hearing,

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    Generic Name

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    Shaina
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    Ranitidine is a histamine H2 receptor antagonist used to inhibit gastric acid secretion and reduce gastric volume. It works by inhibiting histamine action at H2 receptors in gastric parietal cells. Common side effects include headache, abdominal pain, agitation, and hair loss. Nurses should assess for abdominal pain or distress and monitor for potential side effects. Vancomycin is a glycopeptide antibiotic that inhibits bacterial cell wall synthesis. It works by binding to terminal amino acids during cell wall synthesis, inhibiting transpeptidation and preventing further cell wall formation. Potential adverse effects include nephrotoxicity, ototoxicity, and red man syndrome. Nurses should monitor renal function, hearing,

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    Ranitidine is a histamine H2 receptor antagonist used to inhibit gastric acid secretion and reduce gastric volume. It works by inhibiting histamine action at H2 receptors in gastric parietal cells. Common side effects include headache, abdominal pain, agitation, and hair loss. Nurses should assess for abdominal pain or distress and monitor for potential side effects. Vancomycin is a glycopeptide antibiotic that inhibits bacterial cell wall synthesis. It works by binding to terminal amino acids during cell wall synthesis, inhibiting transpeptidation and preventing further cell wall formation. Potential adverse effects include nephrotoxicity, ototoxicity, and red man syndrome. Nurses should monitor renal function, hearing,

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    22 views3 pages

    Generic Name

    Uploaded by

    Shaina
    Ranitidine is a histamine H2 receptor antagonist used to inhibit gastric acid secretion and reduce gastric volume. It works by inhibiting histamine action at H2 receptors in gastric parietal cells. Common side effects include headache, abdominal pain, agitation, and hair loss. Nurses should assess for abdominal pain or distress and monitor for potential side effects. Vancomycin is a glycopeptide antibiotic that inhibits bacterial cell wall synthesis. It works by binding to terminal amino acids during cell wall synthesis, inhibiting transpeptidation and preventing further cell wall formation. Potential adverse effects include nephrotoxicity, ototoxicity, and red man syndrome. Nurses should monitor renal function, hearing,

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    GENERIC NAME: MECHANISM OF ACTION: SIDE EFFECTS/ADVERSE NURSING RESPONSIBILITY

    REACTION
    ranitidine Inhibits histamine action at histamine H2-
    receptors of gastric parietal cells. Common side effects: Baseline assessment
    Therapeutic Effect: Inhibits gastric acid  Obtain history of epigastric/abdominal pain.
    secretion. Reduces gastric volume, hydrogen  headache  Intervention/evaluation
    ion concentration.  abdominal pain  Assess mental status in elderly. Question
     agitation present abdominal pain, GI distress.
    BRAND NAME: INDICATION:  hair loss Patient/family teaching
     confusion • Smoking decreases effectiveness of medication.
    Zantac Prevention of duodenal ulcer.
     constipation
     Do not take medicine within 1 hr of
     diarrhea
    magnesium- or aluminum-containing antacids.
     dizziness
    • Transient burning/pruritus may occur with IV
    DRUG ILLUSTRATION:  hypersensitivity
    administration.
    reaction
    • Report headache.
     nausea
     vomiting • Avoid alcohol, aspirin.
     anemia
     necrotizing
    inflammation of the
    small intestine and
    colon in fetus or
    newborn

    CLASSIFICATION: CONTRAINDICATION:

    Histamine H2-receptor antagonist Hypersensitivity to ranitidine. OTC: Do not


    DOSAGE/FREQUENCY/ROUTE use if trouble or pain when swallowing food,
    vomiting with blood, or bloody or black stool
    2.5 mg IV q8 is present. Do not use 150 mg with kidney
    disease (unless medically advised).
    Cautions: Renal/hepatic impairment, elderly
    pts, history of acute porphyria.

    GENERIC NAME: MECHANISM OF ACTION: SIDE EFFECTS/ADVERSE REACTION NURSING RESPONSIBILITY


    vancomycin Inhibits cell wall synthesis by binding
    to the D-Ala-D-Ala terminal of the
    growing peptide chain during cell wall Side effects Baseline assessment
    synthesis, resulting in inhibition of the • Frequent: • Avoid other ototoxic, nephrotoxic
    transpeptidase, which prevents further PO: Bitter/unpleasant taste, nausea, medications if possible.
    elongation and cross-linking of the vomiting, mouth irritation (with oral • Obtain culture, sensitivity test before
    peptidoglycan matrix (see glycopeptide solution). giving first dose (therapy may begin
    pharm). • Rare: before results are known).
    BRAND NAME: INDICATION: Parenteral: Phlebitis, • Consider placement of central venous
    thrombophlebitis, pain at peripheral line/PICC line.
    Vancocin life threatening infections, sepsis IV site, dizziness, vertigo, tinnitus, Intervention/evaluation
    chills, fever, rash, necrosis with • Monitor serum renal function tests,
    extravasation. I&O. Assess skin for rash.
    DRUG ILLUSTRATION: PO: Rash. • Check hearing acuity, balance.
    Adverse effects/toxic reactions • Monitor B/P carefully during infusion.
    Monitor for "red man"syndrome.
    • Nephrotoxicity (acute kidney injury, • Evaluate IV site for phlebitis (heat,
    acute tubular necrosis, renal failure), pain, red streaking over vein).
    ototoxicity (temporary or permanent • Obtain vancomycin peak/trough level
    hearing loss) may occur. as ordered by physician or pharmacist
    • Therapeutic serum level: peak: 20–40
    • Too-rapid infusion may cause "red
    mcg/mL; trough: 10–20 mcg/mL.
    man syndrome," a common adverse
    • Toxic serum level: peak: greater than
    reaction characterized by pruritus,
    40 mcg/mL; trough: greater than 20
    urticaria, erythema, angioedema,
    mcg/mL.
    tachycardia, hypotension, myalgia,
    Patient/ family teaching
    maculopapular rash (usually appears
    • Continue therapy for full length of
    on face, neck, upper torso).
    CLASSIFICATION: CONTRAINDICATION: treatment.
    • Cardiovascular toxicity (cardiac • Doses should be evenly spaced.
    Tricyclic glycopeptide antibiotic. Hypersensitivity to vancomycin. depression, arrest) occurs rarely. • Report ringing in ears, hearing loss,
    DOSAGE/FREQUENCY/ROUTE Cautions: Renal impairment; Onset usually occurs within 30 min changes in urinary frequency or
    concurrent therapy with other ototoxic, of start of infusion, resolves within consistency.
    40 mg + 10cc PNSS infuse over 30 nephrotoxic medications, elderly pts, • Lab tests are important part of total
    hrs following infusion. May result
    mins IV q6 dehydration. from too-rapid rate of infusion. therapy.
    References:

    Clinical Pathway:

    Karen G. (2018). “Imperforate Anus”. Retrieved from https://www.healthline.com/health/imperforate-anus

    Belleza M. (2021). “Imperforate Anus”. Retrieved from https://www.healthline.com/health/imperforate-anus

    NCP:

    Wayne G. (2022). “Impaired Tissue Integrity & Wound Care Nursing Care Plan”. Retrieved from https://nurseslabs.com/impaired-tissue-integrity/

    RNlessons. (2022). “Wayne BSN, RN. 2022. “Impaired Tissue Integrity & Wound Care Nursing Care Plan”. Retrieved from https://rnlessons.com/impaired-skin-integrity/

    Wagner, M. (2021). “Impaired Skin Integrity Nursing Diagnosis & Care Plan”. Retrieved from https://www.nursetogether.com/impaired-skin-integrity-nursing-diagnosis-care-
    plan/

    DS:

    Kizior Robert J. BS, RPh. & Hodgson, Keith J. RN, BSN, CCRN. Sauders Nursing Drug Handbook 2019. Elsevier
    AFT Pharmaceuticals Ltd. Ranitidine Hydrochloride 150 mg/10 mL Syrup data sheet September 2018. Medsafe. http://www.medsafe.govt.nz. Accessed 15/09/2022.

    GreenPharmacy (2023). “VANCOMYCIN HCL 1 GM” Retrieved from. https://greenpharmacyonline.com/rx-products/vancomycin-hcl-1-gm.html

    Caspian Tamin (2023). “Ranitidine. Retrieved from. https://www.caspiantamin.com/en/product/ranitidine

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