DRUG ANALYSIS

SPECIFIC CONTRAINDIC DRUG ADVERSE SPECIFIC NURSING

NAME OF DRUG INDICATION
ACTION ATION INTERACTION REACTION PRECAUTION RESPONSIBILITIES
Generic Name: Thought to produce Mild pain or Fever Contraindicated in Drug-drug: CNS: Agitation , axiety, May decrease neutrophil, Administer to child only
Acetaminophen analgesia by patients Barbiturates, fatigue, headache, WBC, RBC, and platelet after bowel sounds have
inhibiting hypersensitivity to carbamazepine, counts returned or oral feeding has
insomnia, pyrexia
Brand Name: prostaglandin and drug. I.V. form is hydantoins…; High resumed
doses or long term use of
Tylenol other substances that contraindicated in CV: Peripheral edema, May increase AST level.
these drugs may reduce
sensitize pain patients with therapeutic effects and tachycardia May decrease glucose, Use cautiously when
Dosage: receptors. Drug may severe hepatic enhance hepatoxicity potassium, phosphorus, preparing and administering
relieve fever impairment or effect of acetaminophen. GI: diarrhoea, nausea, magnesium, albumin, and Oral acetaminophen to
Mild pain or Fever. through central severe active liver Avoid using together vomiting, abdominal Hb level and hematocrit avoid overdosing.
Children ages 4 to 11 action in the disease. pain, constipation
months: 80mg P.O. (oral hypothalamic heat- Busulfan: may increase
Maximum daily dose Consider reducing total
suspension, drops, or regulating center. Use cautiously in busulfan level
Metabolic: includes all routes of daily dose and increasing
liquid) every 4 hours patients with any Hypovolemia, administration and all dosing intervals in patients
Dasatinib: May enhance
p.r.n. maximum, five type of liver hepatoxic effects of hypomagnesaemia, acetaminophen-containing with hepatic or renal
doses/day. disease dasatinib and increase hypoglycaemia products, including impairment.
acetaminophen level combination products.
Route: Respiratory: Abnormal Tell parents to consult
P.O. Isoniazid: May increase breath sounds. Dyspnea, May cause serious, prescriber before giving
risk of acetaminophen
hypoxia, atelectasis, potentially fatal skin drug to the child
adverse effects. Monitor
Therapeutic class: pleural effusion reaction, including Stevens-
patient
Analgesics Johnson syndrome, toxic Advise parents that drug is
Skin: rash, uticaria epidermal necrolysis, and only for short term use
Pharmacologic Class:
acute generalize
Para-aminophenol
exanthematous pustulosis. Warn parents that high
derivatives
Reaction may occur with doses or unsupervised long-
first or subsequent use term use can cause liver
Reference:
when acetaminophen is damage.
Nursing 2021 Drug
used as monotherapy or
Handbook
when it is one component Caution parents to contact
of combination drug health care provider if signs
therapy and symptoms of liver
damage (illogical thinking,
severe dyspepsia, jaundice,
and weakness) occur.