SET-3

Series AABB1/2 àíZ-nÌ H$moS>

Q.P. Code 57/2/3
amob Z§. narjmWu àíZ-nÌ H$moS> >H$mo CÎma-nwpñVH$m Ho$
Roll No. _wI-n¥ð >na Adí` {bIo§ &
Candidates must write the Q.P. Code
on the title page of the answer-book.

H¥$n`m Om±M H$a b| {H$ Bg àíZ-nÌ _o§ _w{ÐV n¥ð> 15 h¢ &

àíZ-nÌ _| Xm{hZo hmW H$s Amoa {XE JE àíZ-nÌ H$moS> H$mo narjmWu CÎma-nwpñVH$m Ho$ _wI-n¥ð>
na {bI| &
H¥$n`m Om±M H$a b| {H$ Bg àíZ-nÌ _| >13 àíZ h¢ &
H¥$n`m àíZ H$m CÎma {bIZm ewê$ H$aZo go nhbo, CÎma-nwpñVH$m _| àíZ H$m H«$_m§H$ Adí`
{bI| &
Bg àíZ-nÌ 15 {_ZQ >H$m g_` {X`m J`m h¡ & àíZ-
_| 10.15 ~Oo {H$`m OmEJm & 10.15 ~Oo go 10.30 ~Oo VH$ N>mÌ Ho$db àíZ-
Am¡a Bg Ad{Y Ho$ Xm¡amZ do CÎma-nwpñVH$m na H$moB© CÎma Zht {bI|Jo &
Please check that this question paper contains 15 printed pages.
Q.P. Code given on the right hand side of the question paper should be
written on the title page of the answer-book by the candidate.
Please check that this question paper contains 13 questions.
Please write down the serial number of the question in the
answer-book before attempting it.
15 minute time has been allotted to read this question paper. The question
paper will be distributed at 10.15 a.m. From 10.15 a.m. to 10.30 a.m., the
students will read the question paper only and will not write any answer on
the answer-book during this period.

Ord {dkmZ (g¡ÕmpÝVH$)

BIOLOGY (Theory)

:2 : 35
Time allowed : 2 hours Maximum Marks : 35

57/2/3 1 P.T.O.
 :
:
(i) 13
(ii)
(iii)
(iv) 6 2
(v) 6 3
(vi) 5
(vii) :

(viii)

IÊS> A
1. EH$ amoJr {OgH$m A§J àË`mamonU hmoZm h¡, H$mo à{Vajm {ZamoYH$ (Bå`wZmogàog|Q>) {X`m OmVm
h¡ & Bg à{Vajm {ZamoYH$ H$m Zm_ {bIH$a CgHo$ òmoV Ord H$m Zm_ {b{IE & 2
2. `Ú{n \$mBbo[aE{gg _maH$ (KmVH$) amoJ Zht h¡, naÝVw _mZd _| `h amoJ H$m\
{dê$nVmAm| Am¡a {dH$bm§JVm H$m H$maH$ h¡ & Eogo {H$Ýht Xmo hoqë_W H¥${_ Ho$ d¡km{ZH$ Zm_
{b{IE Omo Bg amoJ Ho$ H$maH$ h¢ VWm \$mBbo[aE{gg Ho$ H$maU Xmo XrK©H$m{bH$ à^mdm|
(A{^ì`{º$`m|) H$m CëboI ^r H$s{OE & 2
3. (H$) ZrMo {XE JE J«m\$ (X) VWm (Y) _| n¥Ïdr na OZdar go {Xgå~a VH$ Ho$ dm{f©H$ gm¡a
{d{H$aU n[adV©Z H$mo Xem©`m J`m h¡ & BgH$m AÜ``Z H$a g§~§{YV àíZm| Ho$ CÎma
Xr{OE &

(i) J«m\$ H$mo nhMm{ZE Omo H«$_e: (I) CîUH${Q>~§Yr` joÌ, VWm (II) erVmoîU joÌ
Xem©Vm h¡ &

57/2/3 2
General Instructions :
Read the following instructions very carefully and strictly follow them :
(i) This question paper consists of 13 questions.
(ii) All questions are compulsory.
(iii) The question paper has three sections Section A, B and C.
(iv) Section A has 6 questions of 2 marks each.
(v) Section B has 6 questions of 3 marks each.
(vi) Section C has a case-based question of 5 marks.
(vii) There is no overall choice in the question paper. However, internal choices
have been provided in some questions. Attempt only one of the alternative
in such questions.
(viii) Wherever necessary, neat, proportional and properly labelled diagrams
should be drawn.
SECTION A
1. A patient who has undergone an organ transplant is put on

organism. 2
2. Though filariasis is not fatal, but the disease in humans is responsible for
considerable suffering, gross deformities and disability. Write the
scientific name of any two helminth worms causing the disease and state
two chronic manifestations of filariasis. 2

3. (a) Study the given graphs (X) and (Y) depicting the annual variation
in solar radiation on Earth from January to December and answer
the undermentioned questions.

(i) Identify the graph that depicts (I) tropical region, and
(II) temperate region, respectively.

57/2/3 3 P.T.O.
 (ii) joÌ AWdm joÌ (Y) _| go H$m¡Z-gm joÌ A{YH$ O¡d {d{dYVm Xem©EJm
(X)
? Xmo H$maU Xr{OE & 2
AWdm
(I) (i) gZ² 1920 Ho$ Amaå^ _| O~ Am°ñQ´>o{b`m _| ZmJ\$Zr H$mo bm`m J`m Vmo CgZo
dhm± ~hþV VoOr go \¡$b H$a V~mhr _Mm Xr VWm ~hþV A{YH$ g_pîQ> KZËd
dmbr àOm{V ~Z H$a nm[aV§Ì H$mo ApñWa H$a {X`m & BgHo$ dhm± bmIm|
\¡$bZo Ho$ H$maU H$s ì`m»`m H$s{OE &
(ii) EH$ Amdmg _| {eH$ma VWm na^jr Ho$ nmañn[aH$ g§~§Y Ho$ _hÎd H$m
CëboI H$s{OE & 2

4. ~m`moJ¡g g§`§Ì VWm Ho$ ZrMo {XE JE AmaoIm| H$m AÜ``Z H$aHo$ g§~§{YV
{ZåZ{b{IV àíZm| Ho$ CÎma Xr{OE :

Cn`w©º$ ~m`moJ¡g g§`§Ì _| go {H$g g§`§Ì H$m Cn`moJ J¡gr` BªYZ VWm {dÚwV Ho$ CËnmXZ Ho$
? AnZo CÎma H$s nwpîQ> _| g_w{MV H$maU {b{IE & 2

5.
~mha OmZo go nyd© CÝh| dhm± H$s n[apñW{V`m§o Ho$ à{V H$_-go-H$_ Xmo {XZm| VH$ n`m©ZwHy${bV
hmoZo H$s gbmh Xr OmVr h¡ & g_PmBE {H$ do {H$g àH$ma n`m©ZwHy${bV hmoVo h¢ & 2

6. (H$)
OmVr h¡, AWm©V² dh g§H«$_U {OÝh| g_` ahVo BbmO Ûmam Q>mbm Om gH$Vm Wm &
(i) EM.AmB©.dr. Ho$ amoJr H$s g_`mZwdVu g§H«$_U hmoVr
h¡ ? {H$gr EH$ H$maU H$m CëboI H$s{OE &
57/2/3 4
 (ii) Which of the two regions, (X) or (Y), will show high biological
diversity and why ? Give two reasons. 2
OR

(b) (i) When prickly pear cactus was introduced into Australia in
early 1920s, it caused havoc and ecosystem instability by
achieving very high population densities. Explain the reason
for its rapid spread into millions of hectares of rangeland.

(ii) St -
habitat. 2

4. Study the given diagrams of Biogas plants

questions that follow :

Which one of the two biogas plants can be used for generating gas fuel and
electricity and why ? Give suitable reasons in support of your answer. 2

5. When tourists go to places of high altitude like Rohtang Pass or

Mansarovar, they are advised not to venture out for two days at least to
get acclimatized to the prevailing conditions there. Explain how they get
acclimatized. 2

6. (a) A person suffering from AIDS dies of opportunistic infections

(ARC) i.e., infections that could have been otherwise overcome.
(i)

57/2/3 5 P.T.O.
 (ii) EH$ OrdmUw VWm EH$ naOrdr H$m d¡km{ZH$ Zm_ {b{IE Omo _w»`V: ES²>g
g§H«${_V ì`{º$ na h_bm H$a gH$Vo h¢ &
(iii) ES²>g Ho$ {bE ì`mnH$ ê$n go Cn`moJ {H$E OmZo dmbo Z¡Xm{ZH$ narjU H$m
nyam Zm_ {b{IE & 2
AWdm
(I) Yy_«nmZ d go g§~§{YV {gJaoQ> Ho$ n¡Ho$Q>m| na
N>nr MoVmdZr Ho$ ~mdOyX g_mO _| Yy_«nmZ H$s AmXV ~Zr hþB© h¡ & Yy_«nmZ H$aZo
2

IÊS> ~
7. AmYw{ZH$ àm¡Úmo{JH$s H$s AmZwd§{eH$ B§Or{Z`[a¨J VH$ZrH$m| Ho$ {dH$mg go A~ h_ S>r.EZ.E.

ì`m»`m H$s{OE & 3

8. (H$) nwZ`m©oJO S>r.EZ.E. àm¡Úmo{JH$s Ho$ {dH$mg go gwajmË_H$ àmoQ>rZ à{VOZ ({Ogo
(Q>rHo$) Ho$ ê$n _| Cn`moJ {H$`m Om gH$Vm h¡) H$m {H$gr {df_OmV
(hoQ>oamobmoJg) V§Ì/OrdmUw AWdm AÝ` {H$gr nanmofr _| A{^ì`º$ hmoZm g§^d hmo

VWm à`wº$ nanmofr H$m Zm_ {b{IE &

(I) O~ H$moB© amoJOZH$ _mZd eara _| à{dîQ> hmoVm h¡, Vmo Vab à{Vajm AZw{H«$`m
(øy_moab Bå`yZ V§Ì) {H$g àH$ma {H«$`merb hmo OmVm h¡ ? ì`m»`m H$s{OE & 3

9. (H$) {H$gr nm[aV§Ì _| Hw$N> àOm{V`m± (ñnrerµO) nm[aV§Ì Ho$ _w»` H$m`mªo H$mo AÝ`
ñnrerµO H$s Anojm A{YH$ à^m{dV H$aVr h¢ & nm°b Eha{bH$ Zo AnZr [adoQ>
nmona n[aH$ënZm Ûmam BgH$s ì`m»`m {H$g àH$ma H$s ? 3

AWdm
(I) (i) O~ ZmBb nM© H$mo nyd© A\
H$s ñWm{ZH$ àOm{V`m| na {H$g à ?

(ii) Eogr Xmo {dXoeO IanVdma àOm{V`m| (ñnrerµO) Ho$ Zm_ {b{IE Omo h_mao
Xoe H$s XoeO àOm{V`m| Ho$ ApñVËd Ho$ {bE {dZmeH$mar {gÕ hþB© h¢ & 3

57/2/3 6
 (ii) Give the scientific name of one bacterium and one parasite
which mainly attack a person suffering from AIDS.
(iii) Write the full form of the name of the widely used diagnostic
test for AIDS. 2
OR
(b) In spite of the statutory warning on cigarette packets against

prevalent in the society. Enumerate four important health hazards

to a smoker. 2

SECTION B

7. With the advent of sophisticated techniques of genetic engineering, we

can now readily purify and isolate DNA. Name and explain the different
steps involved in the separation and isolation of DNA fragments once cut
by restriction endonucleases. 3

8. (a) Development of recombinant DNA technology has made the

in heterologous systems/bacteria or any other organism. Give an

example of a vaccine developed by such a technology and the host
used.
(b) Explain how a humoral immunity system gets into action when a
foreign antigen enters into a human body. 3

9. (a) ce in driving

3
OR
(b) (i) How has the introduction of Nile Perch into Lake Victoria in
East Africa had a devastating effect on the indigenous
species in the lake ?
(ii) Name two invasive weed species which have posed a threat
to the existence of our native species. 3

57/2/3 7 P.T.O.
10. O~ ñn. (_bo[a`m naOrdr) _mZd eara _| à{dîQ> hmoVo h¢ V~ `h Ab¢{JH$
àOZ Bg Ad{Y _| à^m{dV ì`{º$ _bo[a
(g§H«${_V) ahVm h¡ & Ab¢{JH$ àOZZ Ho$ AZoH$ MH«$m| Ho$ ~mX naOrdr AnZm OrdZ MH«$
nyam H$aZo hoVw b¢{JH$ àmdñWm _| àdoe H$aVm h¡ & O~ EH$ _mXm _ÀN>a g§H«${_V
amoJr H$mo H$mQ>Vr h¡, Vmo Ho$ OrdZ MH«$ _|
Ho$ ~ZZo VH$ Ho$ {d{^Þ b¢{JH$ MaUm| H$mo Xem©BE & 3

11. ZrMo {XE JE {MÌ _| EH$ àmH¥${VH$ ~¥hV² Amdmg H$mo Xem©`m J`m h¡, Omo _mZd J{V{d{Y`m|
Ho$ H$maU H«${_H$ ê$n go bJmVma N>moQ>o -N>moQ>o IÊS>m| _| {d^m{OV hmoVm Om ahm h¡ & `h

JB© h¢ &

Amdmg _| ~Zo N>moQ>o-N>moQ>o IÊS Ho$ H$maU Amdmg hm{Z>

(H$) ? AnZo CÎma H$s nwpîQ> _| Xmo g_w{MV H$maU
Xr{OE &
(I) _m¡{bH$ Amdmg H$m Bg àH$ma IÊS>m| _| {d^mOZ Ho$ {bE nm[apñW{VH$ eãXmdbr H$m
Zm_ {b{IE & 3

12. H¥${f _| O¡d àm¡Úmo{JH$s H$m EH$ Cn`moJ OrdmUw Ho$ H«$mB© OrZm| Ûmam

(H$) {H$g {d{eîQ> Bt H$m°Z© ~moaa)

H$mo {Z`§{ÌV H$aVm h¡ ?
(I) OrdmUw Ûmam {Z{_©V Bt {df H$sQ> H$mo {H$g àH$ma _ma XoVr h¡ ? ì`m»`m H$s{OE & 3

57/2/3 8
10. When Plasmodium sp. (malarial parasite) enters the human body, it
reproduces asexually and increases its number. During this course, the
affected person suffers from malaria. After a number of asexual cycles,
the parasite, in order to complete its life cycle, enters the sexual phase of
its life. Trace the sexual stages in the life cycle of Plasmodium in a
female Anopheles mosquito, when it bites an infected person, up to the
formation of mature infective stages of the parasite. 3

11. Given below is a picture of a natural large habitat that is being

continuously broken into smaller patches. This process is continuing,
increasing and expanding over time due to human impact, thereby posing
a great risk to the existence of species in the habitat.

Habitat loss due to creation of patches in a habitat

(a) Do you agree with the above statement ? Give two suitable reasons
in support of your answer.

(b) Write the ecological term used for such patches formed in an
original habitat. 3

12. An application of biotechnology in agriculture involves production of pest

Bacillus thuringiensis.

(a) Proteins coded by which specific Bt toxin genes control corn borer ?

(b) How does Bt toxin produced by the bacteria kill the insect ?
Explain. 3
57/2/3 9 P.T.O.
 IÊS> g
13. (H$) nwZ`m©oJO S>r.EZ.E. àm¡Úmo{JH$s Ho$ {dH$mg Zo {M{H$Ëgm VWm H¥${f Ho$ joÌm| _| AZoH$
H«$m§{VH$mar n[adV©Zm| Ho$ XadmOo Imob {XE h¢ & d¡km{ZH$ BgHo$ Cn`moJ go Or{dV
AWdm _¥V H$mo{eH$mAm| go {d{eîQ> ©aU VWm
CZHo$ hoa-\o$a H$aZo _| g_W© hþE h¢ & AmZwd§{eH$ ê$n go Ordm| Ho$ ê$nm§VaU hoVw _w»`
MaUm| H$mo {ZåZ AmaoI Ûmam Xem©`m J`m h¡ & {XE JE AmaoI H$m AÜ``Z H$s{OE
VWm {ZåZ{b{IV àíZm| Ho$ CÎma Xr{OE :

(i) S>r.EZ.E. H$mo H$mQ>Zo Ho$ {bE dmbo

dm§{N>V S>r.EZ.E. H$mo H$mQ>Zo Ho$ {bE Xmo {^Þ-{^Þ àH$ma Ho$ à{V~§YZ
µOm| H$m Cn`moJ {H$`m OmVm h¡ ? H$maU XoVo hþE AnZo CÎma H$s
nw{îQ> H$s{OE &
(ii) MaU (X) _| {dOmVr` S>r.EZ.E. H$mo g§dmhH$ S>r.EZ.E. _| g_m{dîQ>> H$aZo
Ho$ {bE {H$g E§µOmB_ H$m Cn`moJ {H$`m OmVm h¡ ?
(iii) ê$nm§V[aV _| {dOmVr` (~mhar) S>r.EZ.E. H$s AZoH$
à{V{b{n`m| Ho$ {Z_m©U H$mo Xem©Zo dmbo MaU (Y) H$mo {H$g nm[a^m{fH$
eãXmdbr Ûmam OmZm OmVm h¡ ?
(iv) pBR322 _| {ZåZ H$mo Xem©Zo Ho$ {bE AmaoI
~ZmBE :
(I) Q>oQ´>m H$moB© EH$ à{V~§YZ µO ñWb
(II) E§{n{g{bZ à{VamoYr OrZ H$m H$moB© EH$ à{V~§YZ µO ñWb
(III) _yb (ori) ñWb

(v) ßbmpµÁ_S> pBR322 _| rop{H$gH$m Hy$Q> boIZ H$aVm h¡ ? 5 1=5

AWdm
57/2/3 10
 SECTION C

13. (a) Development of recombinant DNA technology has opened gates to

many breakthroughs in the fields of medicine and agriculture. This
has enabled scientists to isolate, sequence and manipulate
individual genes obtained from diverse living or dead cells. Given
below is a diagram showing the basic steps involved in genetically
modifying an organism. Study the given diagram and answer the
questions that follow :

(i) Are two different types of restriction endonucleases used,

one to cut the vector DNA and another to cut the desired
DNA to be cloned ? Support your answer, giving reason.
(ii) Which enzyme is used at step (X) to integrate the foreign
DNA with the vector DNA ?
(iii) What is the term used for step (Y) showing multiple copies
of the foreign DNA being formed in transformed E. coli ?
(iv) Draw a diagram of E. coli cloning vector pBR322 to show the
following :
(I) Any one restriction endonuclease site in tetracycline
resistance gene
(II) Any one restriction endonuclease site in ampicillin
resistance gene
(III)
(v) What does rop code for in plasmid pBR322 ? 5 1=5
OR
57/2/3 11 P.T.O.
 (I) _mZd amoJm| H$s {M{H$Ëgm VWm H¥${f joÌm| Ho$ {Z`§ÌU Ho$ {bE Ama.EZ.E.
ì`{VH$aU (Ama.EZ.E.i) H$s {M{H$Ëgr` EO|Q> Ho$ ê$n _| ~hþV A{YH$ g§^mdZmE±
h¢ & H$moboñQ>oam°b CnmnM` {dH$mam| H$s {M{H$Ëgm _| Ama.EZ.E.i Ho$ Cn`moJ Ho$
AÜ``Z Ho$ {bE EH$ à`moJ {H$`m J`m & Hw$N> bmoJm| _| AmZwd§{eH$ CËn[adV©Z hmoVo
h¢ {Og_| -Y_Zr amoJ hmo OmVo h¢ &

Ho$ ñVa H$mo H$_ H$aZo go {bnmoàmoQ>rZm| H$s g§»`m VWm aº$ H$moboñQ>oam°b H$s
_mÌm _| H$_r Am gH$Vr h¡ &

Q´>ogr {µO_a_¡Z VWm CZHo$ gh`mo{J`m| Zo 2006 _| Ama.EZ.E.i H$m Cn`moJ A_mZd
àmB_oQ²>g dmZam| _| Ho$ ñVa (_mÌm) H$mo H$_ H$aZo Ho$ {bE
{H$`m & (i) dmZam| Ho$ EH$ g_yh H$mo Ama.EZ.E.i {M{H$Ëgm (Aën ì`{VH$mar
Ama.EZ.E., SiRNAs) H$s (1 mg/kg SiRNAs) H$s IwamH$ Xr JB©, (ii) dmZam|
Ho$ Xÿgao g_yh H$mo Ama.EZ.E.i {M{H$Ëgm hoVw (2·5 mg/kg SiRNAs) H$s IwamH$
Xr JB©, VWm (iii) dmZam| Ho$ Vrgao g_yh H$mo {Z`§ÌU à{VXe© hoVw gobmBZ {ZdoeZ
(

à`moJm| go àmßV n[aUm_m| H$mo ZrMo {XE JE J«m\$ Ûmam Xem©`m J`m h¡ :

57/2/3 12
 (b) RNA interference (RNAi) holds great potential as a therapeutic
agent for the treatment of human diseases and as a bicontrol agent
for controlling pests in the agricultural fields. An experiment was
treatment of
disorders of cholesterol metabolism. Some people possess genetic

them to coronary artery diseases.

lipoproteins and lower the blood cholesterol.

Tracy Zimmerman and her colleagues used RNAi in 2006 to reduce

-human primates Cynomolgus monkeys.
(i) One group of monkeys were given RNAi treatment (Small
interfering RNAs, SiRNAs) (doses 1 mg/kg SiRNAs), (ii) Second
group of monkeys were given RNAi treatment (doses 2·5 mg/kg
SiRNAs), and (iii) Third group of monkeys were injected saline as
control .

The results of the experiments are illustrated in the graph given

below :

57/2/3 13 P.T.O.
 (i) dmZam| H$s gobmBZ VWm 2·5 mg/kg SiRNAs Ûmam {M{H$Ëgm Ho$ 264 KÊQ>m|
Ho$ níMmV² àmßV ñV§^m| (X VWm Z) H$s ì`m»`m Amn {H$g àH$ma H$a|Jo ?
(ii) gOrd OJV _| Ordm| Ho$ Cg g§dJ© H$m Zm_ {b{IE {OZ_| Ama.EZ.E.
ì`{VH$aU (RNAi) hmoVm h¡ & ?

(iii) Ama.EZ.E. ì`{VH$aU (Ama.EZ.E.i) Ûmam dm§{N>V OrZ H$mo em§V

? 5

57/2/3 14
 (i) What do you interpret from the bars (X and Z) obtained after
264 hours of treatment of monkeys with saline and
2·5 mg/kg SiRNAs treatment ?

(ii) Name the category of organisms in the living world, where

RNA interference (RNAi) takes place. Why ?

(iii) What is the basic principle involved in RNA interference

(RNAi) in silencing the preferred genes ? 5

57/2/3 P.T.O.