PHARMACEUTICS Notes

PHARMACEUTICS (3)
RRB PHARMACIST CLASSES

BY: SHUBHAM SHARMA
Q1. Match the ingredients according to their purpose in
the formulation and find out correct set
1. Film coating
(P) Sodium benzoate
2. Syrups
(Q) Ethyl cellulose
3. Emulsification
(R) Eudragit
4. Enteric coating
(S) Sucrose
(T) Sodium oleate
(a) 1-P, 2-Q, 3-R, 4-S

(b) 1-R, 2-S, 3-T, 4-Q
(c) 1-T, 2-P, 3-S, 4-Q
(d) 1-R, 2-S, 3-Q, 4-T
Q2. Match the following regions in GIT with the pH
levels indicated from P-T and find out correct answer
1. Mouth
(P) 5-6
2. Stomach
(Q) 6.8-7.5
3. Deodenum
(R) 6.8-7
4. Large intestine
(S) 3-5
(T) 1.5-3
(a) 1-Q, 2-T, 3-S, 4-R

(b) 1-P, 2-R, 3-S, 4-T
(c) 1-S, 2-T, 3-Q, 4-R
(d) 1-R, 2-S, 3-T, 4-P
Q3. In sugar coating of tablets, sub- coating is done
(a) To prevent moisture absorption
(b) To round the edge & build tablet Size
(c) To smoothen the surface
(d) To prevent the tablet from breaking due to vibration

Q4. Some possible causes are mentioned in P-T, for the
following defects during the film coating of tablets. Match them
1. Chipping
(P) Poor spreading during spraying
2. Cracking
(Q) Over heating during spraying
3. Orange peel
(R) Higher internal stresses in Film
4. Blistering
(S) Excessive coating process
(T) Precipitation of polymer due to high temperature/poor solvent
(a) 1-S, 2-R, 3-P, 4-Q

(b) 1-T, 2-S, 3-R, 4-P
(c) 1-P, 2-Q, 3-R, 4-S
(d) 1-R, 2-P, 3-Q, 4-T
Q5. Sub coating is given to the tablets
(a) To increase the bulkiness
(b) To avoid deterioration due to microbial attack
(c) To prevent the solubility in acidic medium
(d) To avoid stickness

Q6. The following ingredients are commonly used as
coating agents for film coating except
(a) CAP
(b) Carnauba wax
(c) HEC
(d) Sodium CMC

Q7. The ingredients mentioned in P-S are used in various stages
of sugar coating of tablets. Match them and find out correct
answer
1. Seal coating
(P) Gelatin
2. Sub coating
(Q) Carnauba wax
3. Syrup coating
(R) PEG 4000
4. Polyshing
(S) Cane sugar
(a) 1-S, 2-P, 3-R, 4-Q

(b) 1-Q, 2-S, 3-R, 4-P
(c) 1-P, 2-Q, 3-R, 4-S
(d) 1-R, 2-P, 3-Q, 4-S
Q8. The courster process can be used to
(a) Coat tablets
(b) Determine the disintegration time
(c) Gas sterilize parenteral solution
(d) Automatic filling of capsules

Q9. Which of the following is the first process that
must occur before a drug can become available for
absorption from a tablet dosage form?
(a) Dissolution of the drug in GI fluids
(b) Dissolution of the drug in epithelium
(c) Ionization of the drug
(d) Disintegration of the drug

Q10. A synthetic sweetening agent which is
approximately 200 times sweeter than sucrose & has
no taste is
(a) Saccharin
(b) Aspartame
(c) Cyclamate
(d) Sorbitol
Q11. Shellac is used the purpose of coating tablets as
(a) Polishing agent
(b) Film coating agent
(c) Enteric coating agent
(d) Sub-coating agent for sugar coating

Q12. Which of the following substance is used as
muco adhesive
(a) Acacia
(b) Sodium CMC
(c) Burnt sugar
(d) Saccharin
Q13. Diclofenac tablet with CAP has been administered to a
patient. Where do you expect the drug to be released?
(a) Stomach
(b) Oral cavity
(c) Small intestine
(d) Liver
Q14. Enteric coated tablet disintegrate in ..……hours in
simulated intestinal fluid
(a) 1
(b) 2
(c) 3
(d) 4
Q15. PH of the small intestine is
(a) 1-2
(b) 3-4
(c) 6
(d) 7-8
Q16. Lozenges were originally named as
(a) Capsule
(b) ODT
(c) Pastillies
(d) Sustained axn tab

A throat lozenge (also known as a cough drop,
sore throat sweet, troche, cachou, pastille or
cough sweet )
Q17. Empty capsule has moisture content in the range of
(a) 60%
(b) 12%-15 %
(c) 50%- 70%
(d) 30%
Q18. Moisture content is determined by
(a) Gas Chromatography
(b) K-F Method
(c) Both
(d) None
Q19. Foam stability is measured by
(a) IR Spectroscopy
(b) UV Spectroscopy
(c) Rotational viscometers
(d) All
Q20. Particle size is determined by
(a) Gas Chromatography
(b) Cascade impactor
(c) Light scatter decay
(d) Both b & c

Q21. Which of the following is not added in lozenges?
(a) Sweetener
(b) Binder
(c) Disintegrant
(d) All
Q22. Department of Transport Test (DOT) is performed
for which of the following?
(a) Aerosols
(b) Glass containers
(c) Capsules
(d) None
Q23. Measurement of particle size in pharmaceutical aerosol is
by
(P) Cascade impactor
(Q) Light scatter decay
(R) K-F method
(S) IR
(a) P, Q
(b) Q, R
(c) R, S
(d) P, S
Q24. Identify the correct non-flammable Propellant
(a) Trichloro monofluoro methane
(b) Dichloro monofluoro methane
(c) Di methyl ether
(d) Di fluoro methane

Q25. Which one of the following device is used to
increase the efficiency of drug delivery via aerosols?
(a) Tube spacers
(b) Metered valves
(c) Actuator
(d) Pressure valve

Q26. To dispense inhalation aerosols, which containers
are used?
(a) Stain less steel containers
(b) Tin plate containers
(c) Glass containers
(d) Al containers
Q27. The equipment listed P-T is used for the identification of
properties of aerosol mentioned below. Match them.
1. Particle size determination

(P) Pycnometer
2. Identification of propellants
(Q) Rotaional viscometer
3. Stability of foam
(R) Tag open cap apparatus
4. Flash point
(S) IR spectroscopy
(T) Cascade impaction
(a) 1-P, 2-Q, 3-R, 4-S

(b) 1-Q, 2-P, 3-S, 4-T
(c) 1-T, 2-S, 3-Q, 4-R
(d) 1-R, 2-S, 3-P, 4-Q
Q28. Among the propellants used in aerosols, one of the
following is used for topical pharmaceutical aerosols
(a) Tri chloro monofluoro methane
(b) Di chloro difluoro methane
(c) Di chloro tetrafluoro ethane
(d) Propane
Q29. Which one of the following propellant is used in
the aerosol for oral use
(a) Propane
(b) Oxygen
(c) Methane
(d) Trichloro monofluoro methane

Q30. pH of human tear is
(a) 7.2
(b) 8
(c) 7.6
(d) 4.6
Q31. Opthalmic solution is sterilized by
(a) Autoclave
(b) Hot air oven
(c) Both
(d) Bacterial filters

Q32. Which of the following one is used to adjust the isotonicity
(a) Dextrose
(b) Boric acid
(c) NaCl
(d) All the above

Q33. Which drug is formulated as first pharmaceutical
aerosol?
(a) Epinephrine
(b) Codeine
(c) Chloropromazine
(d) Probenecid
Q34. Select the equation that gives the rate of drug
dissolution from a tablet
(a) Fick’s law
(b) Henderson-Hassel batch equation
(c) Noyes-Whitney equation
(d) Michelis Menton equation

PHARMACEUTICS Notes

Uploaded by

Copyright:

Available Formats

PHARMACEUTICS Notes

Uploaded by

Document Information

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

PHARMACEUTICS Notes

Uploaded by

Copyright:

Available Formats

PHARMACEUTICS (3)

RRB PHARMACIST CLASSES

(a) 1-P, 2-Q, 3-R, 4-S

(a) 1-Q, 2-T, 3-S, 4-R

(a) To prevent moisture absorption

(b) To round the edge & build tablet Size

(c) To smoothen the surface

(d) To prevent the tablet from breaking due to vibration

(a) 1-S, 2-R, 3-P, 4-Q

(a) To increase the bulkiness

(b) To avoid deterioration due to microbial attack

(c) To prevent the solubility in acidic medium

(d) To avoid stickness

(b) Carnauba wax

(d) Sodium CMC

(a) 1-S, 2-P, 3-R, 4-Q

(a) Coat tablets

(b) Determine the disintegration time

(c) Gas sterilize parenteral solution

(d) Automatic filling of capsules

(a) Dissolution of the drug in GI fluids

(b) Dissolution of the drug in epithelium

(c) Ionization of the drug

(d) Disintegration of the drug

(a) Polishing agent

(b) Film coating agent

(c) Enteric coating agent

(d) Sub-coating agent for sugar coating

(b) Sodium CMC

(c) Burnt sugar

(b) Oral cavity

(c) Small intestine

(d) Sustained axn tab

(c) 50%- 70%

(a) Gas Chromatography

(b) K-F Method

(c) Rotational viscometers

(a) Gas Chromatography

(b) Cascade impactor

(c) Light scatter decay

(d) Both b & c

(b) Glass containers

(P) Cascade impactor

(Q) Light scatter decay

(R) K-F method

(a) Trichloro monofluoro methane

(b) Dichloro monofluoro methane

(c) Di methyl ether

(d) Di fluoro methane

(a) Tube spacers

(b) Metered valves

(d) Pressure valve

(a) Stain less steel containers

(b) Tin plate containers

(c) Glass containers

1. Particle size determination

(a) 1-P, 2-Q, 3-R, 4-S

(a) Tri chloro monofluoro methane

(b) Di chloro difluoro methane

(c) Di chloro tetrafluoro ethane