[LJ 1221] OCTOBER 2016 Sub.

Code :1221

THIRD PROFESSIONAL B.S.M.S. DEGREE EXAMINATION

PAPER II – NOI NAADAL – II
(PRINCIPLES OF MODERN PATHOLOGY)

Q.P. Code : 601221

Time: Three Hours Maximum : 100 Marks
I. Elaborate on: (2 x 15 = 30)
fl;Liu tiuf:

1. Elaborate on “Pathogenesis of oedema” and add a note on any one important

types of oedema.
‘vbkhtpd; ngj;Njhn[dp]pi] tphpthf vOjp VnjDk; Xh; Kf;fpakhd
vbkhitf; Fwpj;J Fwpg;G tiuf?
2. Write an essay on “Pathogenesis Type II Diabetes Mellietus” and give an
account on Diabetic Ketoacidosis.
langl;b]; nky;ypl]; tif II-d; ngj;Njhn[dp]pi] gw;wp xU fl;Liu
vOjp> langl;b]; fPNlhm]pNlhrpiag; gw;wpf; Fwpg;G tiuf?

II. Write Notes on: (10 x 5 = 50)

RUf;fp tiuf:

1. Explain Radiation carcinogenesis.

NubNard; fhh;rpNdn[dp]p]; gw;wp tpthp?
2. Give an account of the pathological changes which occurs in articular cartilagec
and bone in degenerative joint disease (osteo arthritis).”
Bn[ndNul;bt; %l;L Nehapy; (M];bNah Mh;j;iul;B];) Mh;l;bf;Fshh;
fhh;l;bNy[; kw;Wk; vYk;Gfspd; Vw;gLk; ngjyh[pfy; khWghLfisf;
Fwpj;J Fwpg;G tiuf?
3. Write about the sequence of events in the pathogenesis of Human Immuno
Deficiency Virus (HIV) infection.
`PAkd; ,k;KNdh bgp]pad;]p itu]pdhy; Vw;gLk; ngj;Njhn[dp]pi]
epfo;Tfis njhlh;GgLj;jp vOJf?
4. Give an account
a. Common enzyme markers of cell death.
b. Important tumour markers.
Fwpg;G tiuf.
a. nry; nlj;jpy; Vw;gLk; nghJthd vd;irk; khh;f;fh;fs;.
b. Kf;fpakhd ba+kh; khh;f;fh;fs;.
5. Explain the lesions in Vitamin – D deficiency.
itl;lkpd; - D Fiwghl;bdhy; Vw;gLk; Neha;fis tpthp?
 6. Define pathological cellular adaptation and give an account on “Atrophy”
Ngj;jhyh[pf;fy; nry;Yyhh; mlhg;Nl\id tiuaWj;J ml;Nuhgp gw;wp
Fwpg;G tiuf?
7. Write laboratory findings of megaloblastic and haemolytic anaemias.
nkfNyhg;sh];bf; kw;Wk; `PNkhiyl;bf; mdPkpahtpd; Ma;T$l ghpNrhjid
KbTfis vOJf?
8. List out the factors influencing wound healing.
fhak; Fzkhjypd; jhf;fj;ij Vw;gj;Jk; fhuzpfisg; gl;baypLf?
9. Brief note on “Extra hepatic cholestasis”.
‘vf;];l;uh n`g;ghbf; Nfhyp];lhrp];’ gw;wp Fwpg;G tiuf?
10. Write about clinical features and diagnosis of tuberculosis.
,isg;G Nehapd; Neha; FwpFzq;fs; kw;Wk; Neha;f;fzpg;G gw;wp vOJf?

III. Short Answers on: (10 x 2 = 20)

FWfpa tpilia vOJ:

1. What is Myeloid Leukaemoid Reaction?

‘ikyha;L Yfpkha;l; hpahf;rd;’ vd;why; vd;d?
2. What is suppurative arthritis? Give causative agents of suppurative arthritis.
‘rg;GNubt; Mh;j;iul;B];’ vd;why; vd;d? mij cz;lhf;Fk;
Ez;Zaphpfis vOJf?
3. Define granuloma.
‘f;uhDNyhkh – tiuaW.
4. What is Karyotyping? Give its important application.
NfhpNahilgpq; vd;why; vd;d? mjd; Kf;fpa eilKiw gad;ghl;ilf;
Fwpg;gpLf?
5. What is malignant hypertension?
‘Nkypf;dd;l; i`gh;nld;\d; vd;why; vd;d?.
6. Who are called as “Blue Bloaters”?
‘GS g;shl;lh;]’; vd;W ahh; miof;fg;gLfpd;wdh;?
7. Define metaplasia. Give examples?
nklhgpNsrpah tiuaW cjhuzk; jUf?
8. What is cell injury?
‘nry;,d;Rhp’ vd;why; vd;d?
9. Name the three events of ‘Virchow’s triad’
‘tph;rht; biuabd;’ %d;W epfo;Tfs; ahit?
10. What is Philadephia chromosome?
/g;snly;gpah FNuhNkhNrhk; vd;why; vd;d?
********
[LK 1221] MAY 2017 Sub.Code :1221

THIRD PROFESSIONAL B.S.M.S. DEGREE EXAMINATION

PAPER II – NOI NAADAL – II
(PRINCIPLES OF MODERN PATHOLOGY)

Q.P. Code : 601221

Time: Three Hours Maximum : 100 Marks
I. Elaborate on: (2 x 15 = 30)
fl;Liu tiuf:

1. Write an essay on “Embolism”.

‘wl<hizq^l<’!.!hx<xq!gm<Mjv!ujvg/!
2. Explain chemical and biological carcinogens (etiology) and carcinogenesis
(Pathogenesis) of cancer.
!!!!!!-vsibe!lx<Xl<!hbzi\qg<gz<!gii<sqOeio\e<!)Ofib<g<giv{qgt<*!
!!!!!!nke<!gii<sqOeio\eq^q^<!)ohk<Okio\eq^q^<*!hx<xq!uqiquig!uquiq@!
!
II. Write Notes on: (10 x 5 = 50)
RUf;fp tiuf:

1. Write about any one of the Viral haemarrhagic fever.

“juvz<!oalOv\qg<!hQui<gtqz<”!!WOkEl<!ye<jx!wPKg/!
2. Give an account on “Pathogenesis of amyloidosis.”
nolzib<Omi^q^<!.!ohOkio\eq^q^<!hx<xq!Gxqh<H!ujvg/!
3. Distinguish between the following.
a) Nephrotic oedema and nephritic oedema.
b) Dry gangrene and wet gangrene.
gQp<g{<mux<jx!OuXhMk<Kg/!!
!!!!!!!!n*!ofh<Ovicg<!lx<Xl<!ofh<jvcg<!wcli!
N* !cjv!lx<Xl<!oum<!Ogr<gqiqe<!
!
4. Briefly explain late systemic complications of Diabetes Mellitus.
fQiqpqU!Ofibqe<!fim<hm<m!sq^<mlqg<!okimi<Ofib<gjt!SVg<glig!uquiq@!
5. Write about “Aplastic anaemia”.
Whqzi^<cg<!neQlqbijuh<!hx<xq!wPKg@!
6. Briefly explain Etiopathogenesis of “Rheumatoid arthritis”.
ovilmib<m<M!Ni<k<jvm<C^qe<!=CObi!ohk<Okio\eq^qj^!hx<xq!
SVg<glig!uquiq@!
7. Write short note on “Mechanism of evolution of granuloma”.
“g<viEOzili”!wuZ~]e<!hx<xq!Gxqh<H!ujvg@!
8. Briefly explain the etiologic classification and pathogenesis of Hypertension.
oahi<ome<]eqe<!Ofib<g<giv{!ujghiM!lx<Xl<!ohk<Okio\eq^qj^!!
hx<xq!SVg<glig!uquiq@!
 9. Write short note on “Immune Thrombocytopenic Purpura”.
-l<Le<!k<vil<OhijsOmihqeqg<!hi<hqb,vi!hx<xq!sqXGxqh<H!ujvg@!
10. Explain lipid metabolism in the pathogenesis of fatty liver.
!0Ohm<c!zqui<!ohk<Okio\eq^qz<!ogiPh<H!!uti<sqjk!lix<xk<jkh<!
!hx<xq!uquiq@!
!
III. Short Answers on: (10 x 2 = 20)
FWfpa tpilia vOJ:!
!
1. What are teratogens? Give examples.
omvOmio\e<!we<xiz<!we<e@!dkiv{r<gt<!%Xg@!
2. Name two endocrine causes of obesity.
dmz<!hVlje!d{<mig<Gl<!-v{<M!dt<tqjms<!Svh<hq!giv{r<gtqe<!!
ohbi<!kVg@
3. List out any four important complications of wound healing.
gibl<!G{likzqz<!Wx<hMl<!fie<G!Lg<gqb!hg<g!uqjtUgjth<!hm<cbzqMg/!!
4. Who is father of Clinical Pathology? Name the test described by him for urobilinogen.
g<tqeqg<gz<!ohk<kiz\qbqe<!kf<jk!bii<@!b,OvihqzqOeio\e<!g{<mxqkzqz<!nui<!!
uqtg<gqb!om^<m<!ohbjv!wPKg@!!!!
5. Name the following
a) Etiologic factor which is a common denominator in all forms of
Chronic Obstructive Pulmonary Disease (COPD)
b) Fundamental biochemical hallmark of gout.
ohbi<!kVg/!!
!!!!!!!!!!n*!g<vieqg<!nh<^<m<vg<cu<!hz<leiq!c^Q^qe<!ohiKuie!Ofib<g<giv{q/!
!!!!!!!!!!N*!ogtm<ce<!nch<hjm!dbqi<Oukqbqz<!aiz<lii<g</
6. Clinical features of chikungunya virus infection.
sqg<Ge<Geqbi!juv^<!-e<0hg<seqz<!Wx<hMl<!Ofib<!GxqG{r<gt<!biju@!
7. What is latent jaundice?
Ozme<m<!\ie<c^<!we<xiz<!we<e@
8. Write any two important contrasting features of fat soluble and water soluble vitamins.
fQiqz<!gjvBl<!lx<Xl<!ogiPh<hqz<!gjvBl<!jum<mlqe<gtqe<!-V!Lg<gqb!!
OuXhiMgjt!wPKg@!
9. What are labile cells? Give example.
“ozjhz<!osz<gt<”!we<xiz<!we<e@!dkiv{l<!%Xg@!
10.Name the vitamins which are responsible for following deficiency manifestation.
a) Osteomalacia c) Beri – beri
b) Keratomalacia d) Scurvy.
gQp<g<g{<m!sk<K!GjxhiM!Ofib<gTg<Gg<!giv{lie!jum<mlqe<gtqe<!ohbi<gjt!
wPKg@!!
n* N^<cObilOzsqbi! ! -*!!ohiq.ohiq!
!!!!!!N*!ogvOmilOzsqbi! ! =* ^<gi<uq/!
********
[LL 1221] OCTOBER 2017 Sub. Code: 1221

THIRD PROFESSIONAL B.S.M.S. DEGREE EXAMINATION

PAPER II – NOI NAADAL – II

(PRINCIPLES OF MODERN PATHOLOGY)

Q.P. Code : 601221

Time: Three Hours Maximum : 100 Marks
I. Elaborate on: (2 x 15 = 30)
fl;Liu tiuf:

1. Write elaborately about the “Pathophysiology of Thrombosis” and give its

clinical effects.
k<vil<Ohi^q^qe<!ohk<Okihqsqbiz\qjb!uqiquig!wPkq!nke<!uqjtUgjtg<!!
%Xg@!!
2. Explain structural and numerical abnormalities of chromosomes and add a note
on developmental defects.
!!!!!GOviOliOsil<gtqe<!njlh<H!lx<Xl<!w{<gtqe<!liXhiMgjt!uquiqk<K!!!
!!!!!omuzh<ole<mz<!coh0g<jm!hx<xq!Gxqh<H!ujvg@!
!
II. Write Notes on: (10 x 5 = 50)
RUf;fp tiuf:

1. Brief note on “Cellular events of inflammation”.

kihqkk<kqz<!osz<gtqz<!Wx<hMl<!fqgp<Ugjt!Gxqk<K!sqX!Gxqh<H!ujvg@!
2. Write about ‘Complications of obesity’.
dmz<hVleqe<!okimi<!Ofib<gjt!hx<xq!wPKg@!
3. Write clinical application of the following
a. Glucose Tolerance Test (GTT).
b. Glycosylated haemoglobin (HbA1C).
gQp<g<g{<mux<xqe<!Ofibitqbqml<!fjmLjx!hbe<him<jm!wPKg/!!!
a. GTg<Ogi^<!mizve<^<!om^<m<!(GTT).!
b. g<jtgisqOzmm<!aQOliGOtihqe<!(HbA1C).!!!
4. Briefly explain about the etiologic and Laboratory findings of Iron deficiency
anaemia.
-Vl<H!sk<K!Gjxuiz<!Wx<hMl<!neQlqbiuqe<!Ofib<g<giv{r<gt<!lx<Xl<!!
Nb<U!%m!hiqOsikjegjt!SVg<glig!uquiq@!
5. Write about an ill-effects of radiation.
! OvcOb]eqeiz<!Wx<hMl<!kQb!uqjtUgjth<!hx<xq!wPKg@!
6. Write short note on “Protein Energy Malnutrition” (PEM).
 Hvk!sk<K!GjxhiM!hx<xq!sqX!Gxqh<H!ujvg@
7. Briefly explain “Pathogenesis of Leukaemia”.
Zg<gqlqbiuqe<!ohk<okio\eq^q^qj^h<!hx<xq!SVg<glig!uquiq@
8. Give an account on of “Gout”.
ogt0m<!hx<xqg<!Gxqh<H!ujvg@!!
9. Briefly explain “Pathogenesis of Type I Hypersensitivity” and give examples.
oahi<ose<sqcuqm<c!ujg!I.e<!ohk<Okio\eq^qj^!SVg<glig!!
dkiv{r<gTme<!uquiq@!!
10. Write short not on “Pathologic diagnosis of cancer”.
Hx<XOfibqe<!ohk<kizi\qgz<!Ofib<!g{qh<jh!hx<xq!sqX!Gxqh<H!ujvg@!
!
III. Short Answers on: (10 x 2 = 20)
FWfpa tpilia vOJ:!
!
1. Carcinal signs of inflammation.
! kihqkk<kqe<!Lg<gqblie!Ofib<!nxqGxqgt<!biju@!!
2. Name two essential phenomena which distinguish irreversible from reversible
cell injury.
ke<!-bz<H!fqjzjb!njmbik!osz<!hikqh<Hgjt!ke<!-bz<H!fqjz!!
njmBl<!osz<!hikqh<HgtqzqVf<K!OuXhMk<kqg<!gim<Ml<!-V!Lg<gqb!!
G{r<gjt!ohbiqMg@
3. Define stable cells-Give examples.
! ^<Omhqz<!osz<gt<!we<xiz<!we<e@!dkiv{r<gt<!kVg@!
4. Name the deficiency manifestation of any four important minerals.
! WOkEl<!fie<G!Lg<gqb!lqevz<gtqe<!Gjxhim<cje!ohbiqMg@!!!!
5. Who developed Pap test? Give its clinical application.
“Ohh<!om^<jm”!dVuig<gqbK!bii<@!nke<!fjmLjx!hbe<him<jm!wPKg@!
6. Mention the stages of shock.
! nkqi<s<sqbqe<!fqjzgjtg<!Gxqh<hqMg@!
7. Name any four Clostridial diseases?
g<ti^<cbiuqeiz<!uVl<!WOkEl<!fie<G!Ofib<gtqe<!ohbi<gjt!wPKg@
8. Give two clinical applications of Polymerase Chain Reaction (PCR).
hizqolOv^<!osbqe<!iqbig<seqe<<!-V!fjmLjx!hbe<him<jmg<!%Xg@!!
9. List out the risk factors modifying the course of essential hypertension.
wo^e<sqbz<!jahi<ome<seqe<!Ohig<jg!liXhMk<Kl<!giv{qgjt!!
hm<cbzqMg@!
10. Write two important causes of obstructive jaundice.
!!!!!Nh<^<vg<cu<!\ie<c^qg<gie!-V!Lg<gqb!giv{r<gjt!wPKg@!
********
[LM 1221] MAY 2018 Sub. Code: 1221

THIRD PROFESSIONAL B.S.M.S. DEGREE EXAMINATION

PAPER II – NOI NAADAL – II

(PRINCIPLES OF MODERN PATHOLOGY)

Q.P. Code : 601221

Time: Three Hours Maximum : 100 Marks
I. Elaborate on: (2 x 15 = 30)
fl;Liu tiuf:

1. Define Cell injury. What are the various forms of cellular response to an injury?
Explain the mechanism and morphology of irreversible cell injury.
nry; ,d;Rhpia tiuaWj;J mjd; khWghLfis tpsf;Ff. kw;Wk; kPs;
nry; rpijT Vw;gLk; tpjj;ij tpsf;Ff.

2. Write in detail about etiology, mode of spread, types, fate and complications
of Tuberculosis.
Ba+gh; FNshrp]; Nehapd; tUk; top> guTk; tpjk;> mjd; KbT>
rpf;fy;fis tpthp.
!!!!!!
II. Write Notes on: (10 x 5 = 50)
RUf;fp tiuf:

1. Write the TNM staging of cancer.

Nfd;rh; Nehapd; TNM epiyfis tpthp?

2. Write about necrosis and its types.

nef;Nuhrp];rpd; tiffis tpthp.

3. Explain the mechanism involved in oedema due to sodium and water retention.
Nrhbak; kw;Wk; ePh; Njq;Ftjhy; Vw;gLk; tPf;fj;ij tpthp

4. Write about the consequences of pulmonary embolism.

gy;kdhp vk;ghyprj;jpd; khWghLfis tpthp.

5. Explain the cellular events of inflammation.

jhgpjj;jpy; Vw;gLk; nry; khWghLfis tpthp.

6. What are the complications of wound healing?

Gz; Mw;Wjypy; Vw;gLk; rpf;fy;fis tpthp.

7. Explain the morphological features of osteoarthritis.

M];bNah Mh;jpiul;b]pad; GwkhWghLfis tpthp.
 8. Write about ill effects of ionizing radiation.
mad]pq; NubNardpd; ghjpg;Gfis vOJf.

9. Write about the type I hypersensitivity reaction.

i`g;gh; nrd;rpbtpl;b tif II tpthp.

21/ Explain TORCH complex.!

“lhh;r”; fhk;sf;]; tpthp.!
!
III. Short Answers on: (10 x 2 = 20)
FWfpa tpilia vOJ:!
!
1. Write about dystrophic calcification.
b];l;Nuhgpf; fhy;rpgpNfrd; gw;wp vOJf.

2. Define Hyperplasia.
i`g;gh; gpNsrpahit tiuaW.

3. Features of kwashiorkor.
Fthrpahf;fhpd; ,ay;Gfis vOJf.

4. Write shortly on Physical carcinogenesis.

gprpfy; fhh;rpNdh[d;]; gw;wp vOJf.

5. Write about infarction.

,d;gpuhf;rd; gw;wp vOJf.

6. Write lewis experiment.

yptp]; Nrhjidia gw;wp vOJf.

7. Write about cerebral beri-beri.

“nrhpnguy; nghp nghp” I tpthp.

8. Write any two complications of obesity.

Xgprpl;bapd; VjhtJ ,uz;L rpf;fy;fis vOJ.

9. Define RS cells.
RS nry;iy tiuaW.

10. Criggler-najjar syndrome.!

rph;[yh; - ep[hh; rpd;l;Nuhk; gw;wp vOJf.!

********
[LN 1221] OCTOBER 2018 Sub. Code: 1221

THIRD PROFESSIONAL B.S.M.S. DEGREE EXAMINATION

PAPER II – NOI NAADAL – II

(PRINCIPLES OF MODERN PATHOLOGY)

Q.P. Code : 601221

Time: Three Hours Maximum : 100 Marks
I. Elaborate on: (2 x 15 = 30)
fl;Liu tiuf:

1. Define inflammation. Explain the pathogenesis of acute inflammation.

kihqkk<jk!ujvbXk<K!dmec!kihqk!liXhiMgjt!uquiq/!

2. Explain the classification, etiology and pathogenesis of shock.

nkqi<s<sqbqe<!ujggt<?!giv{l<?!ohk<Okio\eq^<!uquiq/
!!!!!!
II. Write Notes on: (10 x 5 = 50)
RUf;fp tiuf:

1. Write about pathogenesis of Bronchiectasis.

hqvir<oag<mi^q^<!.!ohk<Okio\eqj^!uquiq/!

2. Explain hypovolemic shock.

jaOhiOuizqlqg<!nkqi<s<sqjb!uquiq/!

3. Write the structural abnormalities of chromosomes.

GOviOliOsilqe<!dmx<%X!liXhiMgjt!uquiq/!

4. Discuss about the exogenous pigments.

wg<Osi\Qe^<!fqxlqgjt!hx<xq!wPKg/!

5. Write the difference between dry and wet gangrene.

cjv?!oum<!Ogr<iqeqe<!OuXhiMgjt!wPKg/!

6. Write the classifications of Anaemia.

neqlQbiuqe<!ujghiMgjt!uquiq/!

7. How will you differentiate AML from CML.

CML, AML!–!OuXhMk<K/!

8. Write short notes on Injury caused by Radiation.

OvcObse<!sqjkU!hx<xq!wPKg/
 9. Write about infarction.
-e<hqvig<^e<!hx<xq!wPKg/!

10. Explain the pathogenesis of unconjugated hyperbilirubinemia.!

ne<!gi{<\qOgmm<!jahi<hqzqVhqe<eqbiuqe<!ohk<Okio\eqsqj^!uquiq/!
!
III. Short Answers on: (10 x 2 = 20)
FWfpa tpilia vOJ:!
!
1. Define Atrophy.
nm<Ovihqjb!ujvbX/!

2. Write shortly about Pulmonary hypertension.

hz<leiq!jahi<ome<se<!hx<xq!sqX!Gxqh<H!ujvg/!

3. Felty’s Syndrome.
ohz<c!sqe<m<Ovil</!

4. Write any four types of abnormal RBC’S.

liXhm<m!-vk<k!sqgh<h[g<gjt!uquiq/!
!
5. Define phagocytosis and write the steps involved in phagocytosis.
OhOgijsOmisqjz!ujvbjx!osb<K!nke<!upqLjxgjt!wPKg/!

6. Write the fate of pulmonary tuberculosis.

hz<leiq!Cb,hi<GOtisq^qe<!Lcugjt!wPKg/!

7. Short notes on metastatic calcification.

olmi^<Omcg<!giz<sqhqOgse<!hx<xq!sqX!Gxqh<H!ujvg/!

8. Write about “Pickwickian” syndrome.

hqg<uqg<be<!sqe<m<Ovil<!wPKg/!

9. Write complications of malaria.

lOzvqbiuqe<!gil<hqtqOgsje!wPKg/!

10. Local factors determining the wound healing.!

H{<!NXkzqz<!okimi<Hjmb!giv{qgjt!wPKg/!

********
[LO 1221] MAY 2019 Sub. Code: 1221

THIRD PROFESSIONAL B.S.M.S. DEGREE EXAMINATION

PAPER II – NOI NAADAL – II

(PRINCIPLES OF MODERN PATHOLOGY)

Q.P. Code : 601221

Time: Three Hours Maximum : 100 Marks
I. Elaborate on: (2 x 15 = 30)
fl;Liu tiuf:

1. Explain Ischemia.
-^<gQlqbi!hx<xq!uquiq/!
!!
2. Explain Jaundice.
gilijz!Ofib<!hx<xq!uquiq/!!
!!!!!!
II. Write Notes on: (10 x 5 = 50)
RUf;fp tiuf:

1. Write about Pathogenesis of Bronchiectasis.

h<vir<gqbg<Omsq^qe<!ohk<Okio\eq^<!hx<xq!wPKg/!
!
2. What is Hypovolemic shock?
jaOhi!yzqlqg<!]ig<!we<xiz<!we<e@

3. Complication of tuberculosis.
cB,hi<GOzisq^q^qe<!hg<g!uqjtUgjt!wPKg/!

4. Write the complications of Rheumatoid arthritis.

ovilmib<m<!Nv<k<kjvm<C^qe<!sqg<gz<gjt!wPKg/!

5. Write about irreversible cell injury.

-i<iqui<shqt<!osz<!-R<Siq!hx<xq!uquiq/!

6. Explain free radicals mediated cell injury.

h<vQ!Ovcgz<!lQcObm<mM!osz<!-R<Siq!hx<xq!uquiq/!
!
7. Explain the acute complications of Diabetes mellitus.
m<bohm<C^<!olzqm<m^q<e<!ng<gqB,m<!gil<tqOgse<^<!uqtg<Gg/!
!
8. Pathological changes of vitamin A deficiency.
jum<mlQe<!A Gjxhim<cz<!gi{h<hMl<!Ofib<g<Gxqgt</!
 9. Write about pulmonary odema.
hz<Levq!wcli!Gxqk<K!wPKg/!
!
10. Explain Gangrene.
Ogr<g<vQe<!.!uqtg<Gg/!
!
III. Short Answers on: (10 x 2 = 20)
FWfpa tpilia vOJ:!
!
1. Explain - Pathologic calcifications.
ohk<kz\qg<!Ogz<sqhqg<Ogse<!.!uquvq/
2. What is Torch complex?
miv<s<!gil<otg<s<!we<xiz<!we<e@
3. What is over hydration?
Yui<jam<Ovse<!we<xiz<!we<e@
4. What is hyperplacia?
jahv<h<Otsqbi!we<xiz<!we<e@
5. What are the Cardinal signs of inflammation?
-e<ht
< Olseqe<!giv<cez<!jse<gt<!biju@
6. What is Wear and tear pigment?
uqbv<!n{<m<!cbv<!hqg<l{<m<!we<xiz<!we<e@!
7. What is Anisocytosis?
neq^<O^ijsOmi^q^<!we<xiz<!we<e@
8. Kline Felter’s syndrome.
gqjte<!ohz<mi<<!sqe<Ovil<^</
9. What is steatosis?
^<cbOmi^q^<!we<xiz<!we<e@
10. What is atrophy and hypertrophy?
nm<Ovihq!lx<Xl<!jahv<mO < vihq!we<xiz<!we<e@!
!

*********
[LP 1221] OCTOBER 2019 Sub. Code: 1221

THIRD PROFESSIONAL B.S.M.S. DEGREE EXAMINATION

PAPER II – NOI NAADAL – II

(PRINCIPLES OF MODERN PATHOLOGY)

Q.P. Code : 601221

Time: Three Hours Maximum : 100 Marks
I. Elaborate on: (2 x 15 = 30)
fl;Liu tiuf:

1. Explain wound healing.

H{<!NXkjz!uquiq/!

2. Discuss in detail about cellular adaptations.

osz<Zziv<!nmih<Omse<^<!hx<xq!uquvqg<g/!
!
II. Write Notes on: (10 x 5 = 50)
RUf;fp tiuf:

1. Explain pernicious Anaemia.

ohv<eQsqb^<!neQlqbiju!uqtg<Gg/
2. What is Karyotype abnormalities?
OgvqObijmh<!nh<eiv<lzqm<C^<!we<xiz<!we<e@
3. Explian yellow fever.
lR<st<!Svl<!.!uquiq/
4. Explain the disturbances in the volume of circulating blood.
-vk<k!Sx<Oxim<mk<kqe<!ntU!hikqh<H!– uqtg<Gg/
5. Write about Protein energy malnutrition.
HOvim<ce<!wev<\q!liz<fQB,m<CvQse<!we<xiz<!we<e@
6. Explain cholestasis.
Ogizq^<Omsq^<!uqtg<Gg/
7. Explain Amniotic fluid embolism.
nl<eQbicg<!h<Tbqm<!wl<hizqsl<!uqtg<Gg/!
8. Write short notes on repair.
vqh<Ohv<!Gxqk<K!sqXGxqh<H!wPKg/
9. Write notes on types of tuberculosis.
m<Bhv<GOtisq^<!ujggt<!Gxqk<K!wPKg/
10. What is Reiters syndrome?
!!!!!ovb<mv<^<!sqe<Ovil<!we<xiz<!we<e@!
!
III. Short Answers on: (10 x 2 = 20)
FWfpa tpilia vOJ:!
!
1. What is diver’s palsy?
jmuv<^! < hiz<sq!we<xiz<!we<e@
2. Define “bald tongue”and how it occurs?
“hiz<m<!mr<g”< !uqtg<gq?!wu<uiX!uVgqxK!we<hjkBl<!uqtg<Gg/
3. Define pavementation.
Ohu<ol{<Omse<!uqtg<Gg/
4. Auto splenectomy.
Nm<Omi!^<hqtQoeg<mlq!we<xiz<!we<e@
5. Define DIC.
DIC - uqtg<Gg/
6. Explain Madura foot.
lKvi!H,m<!uqtg<Gg/
7. What is cell injury?
osz<!-R<Svq!we<xiz<!we<e@!
8. Write Lewis experiment.
Z~bq^<wg<^<hvqol{<m<!Gxqk<K!wPKg/
9. Write any two complications of obesity.
yhqsqm<cbqe<!WOkEl<!-v{<M!sqg<gzie!fqjzgjt!wPKg/
10. Explain dystrophic calcification.
!!!!!c^<Ovihqg<!Ogz<sqhqg<Ogse<!uqtg<Gg/!

********
 THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
[BSMS 0321] MARCH 2021 Sub. Code: 1221
(MAY 2020 SESSION)
THIRD PROFESSIONAL B.S.M.S. DEGREE EXAMINATION
PAPER II – NOI NAADAL – PAPER II
(PRINCIPLES OF MODERN PATHOLOGY)
Q.P. Code : 601221
Time: Three Hours Maximum : 100 Marks
I. Elaborate on: (2 x 15 = 30)
fl;Liu tiuf:

1. Define Neoplasm. Explain the molecular pathogenesis and diagnosis of cancer.

epNahgpshrk; tiuaiw nra;J mjd; khypFyh; ngj;Njhn[dp];i]Ak;>
Gw;WNehia fzpf;Fk; KiwfisAk; tpthp.

2. Define Embolism and explain any two types.

vk;ghyprk; vd;why; vd;d? mjd; VNjDk; ,uz;L tiffis tpthp.
!!!!!!
II. Write Notes on: (10 x 5 = 50)
RUf;fp tiuf:

1. Write about pathogenesis of Emphysema.

vk;igrPkhtpd; ngj;Njhn[dpi] tpthp.

2. Chemical mediators of inflammation.

jhgpjj;jpd; Ntjpay; fhuzpfis tpthp.

3. Explain the acute complications of Diabetes mellitus.

ilahgpl]; nkypl]pd; cldb gf;f tpsiT Neha;fis tpthp.

4. Explain the pathogenesis of Dengue fever.

nlq;F Ruj;jpd; ngj;Njhn[dprpi] tpthp.

5. Write the diseases caused due to ionizing radiation.

maid]pq; NubNardhy; tUk; Neha;fis tpthp.

6. Write shortly on hyperemia and congestion.

i`gh;hPkpah> fd;[rd; tpthp.

7. Explain amoebic abscess.

“mkPgpf; mg;rpi]” tpsf;Ff.

8. Types of Gangrane.
Nfq;fphpdpd; tiffs;.
9. Structural abnormalities of chromosomes.
 FNuhNkhNrhkpd; clw;$W khWghLfis tpthp.

10. Explain Fatty liver.!

0Ngl;b ypth; tpthp.
!
III. Short Answers on: (10 x 2 = 20)
FWfpa tpilia vOJ:!
!
1. Write the pathogenesis of renal oedema.
uPdy; vbkhtpd; ngj;Njhn[dpri] vOJf.

2. What are lesions in vit. D. deficiency?

jum<mlqe<!D!Gjxhim<jm!wPKg/!

3. Define hypertrophy.
jahi<OmiOvihq!ujvbX/!

4. Write the stages of shock.

nkqi<ss
< qbqe<!ujggjt!wPKg/!

5. What is Virchow cells?

uqi<s<$!osz<!we<xiz<!we<e@!

6. Write about latent jaundice.

Ozme<m<!\ie<c^<!hx<xq!wPKg/!

7. Write shortly on dystrophic calcification.

c^<m<Ovihqg<!giz<sqhqOgse<!hx<xq!sqXGxqh<H!ujvg/!

8. What is fat necrosis?

0Ohm<!ofg<Ovisq^<!we<xiz<!we<e@!

9. Define Anti-oxidants.
N{<c!Ng<^qme<m<!ujvbX/!

10. Write the types of leprosy.!

ozh<vsq!Ofibqe<!ujggjt!wPKg/!

********
 THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[BSMS 0921] SEPTEMBER 2021 Sub. Code: 1221

(OCTOBER 2020 SESSION)

THIRD PROFESSIONAL B.S.M.S. DEGREE EXAMINATION

(Regulations for the candidates admitted from 2013-2014 to 2016-2017 and 2017 onwards)
PAPER II – NOI NAADAL – PAPER II (PRINCIPLES OF MODERN PATHOLOGY)
Q.P. Code : 601221

Time: Three Hours Answer ALL questions Maximum : 100 Marks

I. Elaborate on : 2x15 = 30

fl;Liu tiuf:

1. Write in detail about Oedema.

Vbkh gw;wp tpthp.

2. Write in detail about Anaemia with its classifications.

mdPkpah Fwpj;J tphpthf tpsf;fp> mjd; gphpTfis tphpthf tpsf;Ff.

II . Write notes on: 10x5 = 50

RUf;fp tpil vOJf

1. Short notes on PEM.

gp,vk; gw;wp vOJf.
2. What is Ischaemia.
,];fpkpah vd;why; vd;d?
3. Complications of Thrombosis.
j;uhk;Nghrp]; rpf;fy;fs; tpsf;Ff.
4. Write about Pathogenesis of irreversible cell injury.
,h;hpth;rpgps; nry; ,Q;Rhpapd; ngj;Njhn[dprp]; Fwpj;J vOJf.
5. Short notes on Malaria.
kNyhpah rpW Fwpg;G tiuf.
6. Injury caused by Radiation.
NubNardpdhy; cz;lhFk; rpijT.
7. Complications of Obesity.
cly;gUkdhy; Vw;gLk; rpf;fy;fs; ahit?
 8. Define phagocytosis and write the steps involved in phagocytosis.
NgNfhirl;Nlhrp]; tpsf;Ff. NgNfhirl;Nlhrp]pf;F fhuzkhd topKiwfis
vOJf.
9. Write the pathogenesis of acute inflammation.
mf;a+l;,d;g;sNkrdpd; ngj;Njhn[dprp]; gw;wp vOJf.
10. Short notes on Liver function test.
ypth; /gq;;\d; nl]l; - rpW Fwpg;G tiuf.
III. Write short notes on: 10x2= 20

FWfpa tpilvOJf .

1. Types of microscopes.
ikf;Nuh];Nfhg;]; tiffs;.
2. Write pathogenesis of Leukaemia.
Yf;fPkpahtpd; ngj;Njhn[dprp]; vOJf.
3. What is TNM Staging of cancer.
Nfd;rh; Nehapd; bvd;vk; ];Nl[pq; vd;d?
4. Clinical features of Osteoarthritis.
M];bNahMh;j;iul;b]pd; f;spdpf;fs; gPr;rh;];.
5. Write the clinical applications of PAP test.
Ngg; nl];bd; f;spdpf;fs; mg;spNfrd;]; Fwpj;J vOJf.
6. Causes of Thrombocytopenia.
j;uhk;Nghirl;NlhgPdpah fhuzq;fs; ahit?
7. What is hypertrophy and hyperplasia?
ifgh;l;Nuhgp kw;Wk; ifgh;g;Nsrpah vd;why; vd;d?
8. Give the example for dry gangrene.
l;iu Nfq;fphPDf;F vLj;Jf;fhl;Lj; jUf.
9. Microscopical picture of ALL.
v vy; vy; - fhzg;gLk; Ez;Nzhf;fp tpsf;fk;.
10. Complications of obesity.
xgprpl;bapd; rpf;fy;fs;.
********
 THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[BSMS 0222] FEBRUARY 2022 Sub. Code: 1221

(MAY 2021 EXAM SESSION)

THIRD PROFESSIONAL B.S.M.S. DEGREE EXAMINATION

(Regulations for the candidates admitted from 2013-2014 to 2016-2017 and 2017-2018 onwards)
PAPER II – NOI NAADAL – PAPER II (PRINCIPLES OF MODERN PATHOLOGY)
Q.P. Code : 601221

Time: Three Hours Answer ALL questions Maximum : 100 Marks

I. Elaborate on : 2x15 = 30
!gm<Mjv!ujvg;!
!
1. Explain –Pathogenesis of cell injury.
osz<!-e<\`iq!ohk<Okio\eqsq^<!uquiq/!
!!
2. Explain the mechanism of spreading of Tumour.
Oge<si<!hvUl<!Ljxjb!uquiq/
!
II . Write notes on: 10x5 = 50 !!
!!!RUf;fp tpil vOJf:

1. Write the Investigations of Anaemia.

neQlqbiuqe<!hiqOsikjegjt!uquiq/!
2. Write the TNM staging of Cancer.
Oge<si<!Ofibqe<!fqjzgjt!uquiq/!
3. Write about Pathologic calcification and its types.
Ofib<!fqjz!S{<{hcll<!lx<Xl<!nke<!ujggt<!sqXGxqh<H!ujvg/!
4. Contrasting features of Kwashiorkor and Marasmus.
Gui]qbi<gi<?!lvi^<l^<!OuXhiMgt<!uquiq/!
5. Explain HLA System.
HLA!sq^<ml<!uquiq/!
6. Fate of Thrombus.
vk<k!gm<c!liXkz<!njmBl<!uqkl</!
7. Numerical abnormalities of chromosomes.
GOviOliOsil<gtqe<!w{<!liXhiM!uquiq/!
8. Write short notes on Aplastic anaemia.
whqti^<cg<!neQlqbi!uqtg<Gg/!
9. Fracture Healing.
we<H!OsVkz<!uquiq/!
10. Role of chemical mediators of Inflammation.
kihqkl<!d{<mig<Gukqz<!Oukqbz<!ohiVm<gtqe<!osbz</!

III. Write short notes on: 10x2= 20

 FWfpa tpilvOJf:

1. Drug induced Hemolytic Anaemia.

lVf<Kgtiz<!K~{<mh<hMl<!aQOlijzm<cg<!neQlqbi/!
2. Causes of ischaemia in arteries.
ficgtqz<!-^<gQlqbi!d{<miukx<G!giv{l<
3. KVIEM’s Test
uql<^<!om^<m<!we<hK!we<e/!
4. Purpura.
hi<h<H,vi/!
5. Heart Failure cells.
aii<m<!0ohbqzqbi<!osz<gt</
6. Vitamins which act as Antioxidants.
Ne<m<c!Ng<^qom{<m<!Ng!osbz<hMl<!jum<mlqe<gt<!biju@!
7. Define Dysplasia.
c^<hqOtsqbi!–!ujvbX/
8. Write types of abnormal RBC’s.
liXhm<m!-vk<k!squh<h[g<gjt!wPK/!
9. Complications of obesity.
yhqsqm<cbqe<!sqg<gz<gjt!wPK/!
10. Hb Bart’s Hydrops foetalis.
Hb him<^<!jam<Ovih<^<!h<hQmizq^</
********
 THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[BSMS 0522] MAY 2022 Sub. Code: 1221

(OCTOBER 2021 EXAM SESSION)

THIRD PROFESSIONAL B.S.M.S. DEGREE EXAMINATION

(Regulations for the candidates admitted from 2013-2014 to 2016-2017 and 2017-2018 onwards)
PAPER II – NOI NAADAL – PAPER II (PRINCIPLES OF MODERN PATHOLOGY)
Q.P. Code : 601221

Time: Three Hours Answer ALL questions Maximum : 100 Marks

I. Elaborate on : 2x15 = 30
!gm<Mjv!ujvg;!
!
1. Explain wound healing.
H{<!NXkjz!uquiq/!
!!
2. Discuss in detail about cellular adaptations.
osz<Zzii<!nmih<Omse<^<!hx<xq!uquiqg<g/
!
II . Write notes on: 10x5 = 50 !!
!!!RUf;fp tpil vOJf:

1. Explain pernicious Anaemia.

ohi<eQsqb^<!neQlqbiju!uqtg<Gg/!
!
2. What is Karyotype abnormalities?
OgiqObijmh<!nh<eii<lzqm<C^<!we<xiz<!we<e@!
!
3. Explain Yellow fever.
lR<st<!Svl<!.!uquiq/!
!
4. Explain the disturbances in the volume of circulating blood.
-vk<kl<!Sx<Oxim<mk<kqe<!ntU!hikqh<H!–!uqtg<Gg/!
!
5. Write about Protein energy malnutrition.
HOvim<ce<!wei<\q!liz<fQB,m<CiQse<!we<xiz<!we<e@!
!
6. Explain cholestasis.
Ogizq^<Omsq^<!uqtg<Gg/!
!
7. Explain Amniotic fluid embolism.
nl<eqbicg<!h<Tbqm<!wl<hizqsl<!uqtg<Gg/!
!
8. Write short notes on repair.
Iqh<Ohi<!Gxqk<K!sqXGxqh<H!wPKg/!
P.T.O.
 9. Write notes on types of tuberculosis.
m<Bhi<GOtisq^<!ujggt<!Gxqk<K!wPKg/!
!
10. What is Reiters syndrome?
ovb<mi<^<!sqe<Ovil<!we<xiz<!we<e@!

III. Write short notes on: 10x2= 20

FWfpa tpilvOJf:

1. What is Leukemia?
-vk<k!Hx<X!we<xiz<!we<e@!
!
2. What is miliary T.B?
lqzqbiq!cB,hi<GOtisq^<!we<hK!we<e@!

3. Secondary risk factors predisposing to Thrombus.

k<Ovil<h^<!uv!giv{lie!-v{<mil<!fqjz!iq^<g<!hig<mi<gt<!wju@!
!
4. What is Pathological atrophy?
ohk<kzi\qg<gz<!nm<Ovihq!we<xiz<!we<e@!
!
5. What is steatosis?
^<cbOmisq^<!we<xiz<!we<e@!
!
6. What is Lepra Cells?
ozh<vi!osz<^<!we<xiz<!we<e@!
!
7. Define Pavementation.
Ohu<ole<Omse<!ujvbX/!

8. Write about dystrophic calcification.

c^<m<Ovihqg<!giz<sqhqOgse<!sqXGxqh<H/!
!
9. Explain Cancer diet.
Oge<si<!Ofib<g<gie!d{U!Ljxgt</!
!
10. Pap test – Give its clinical application.
Ohh<!om^<m<!fjmLjx!hbe<him<jm!wPK/
********
 THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[BSMS 1022] OCTOBER 2022 Sub. Code: 1221

(MAY 2022 EXAM SESSION)

THIRD PROFESSIONAL B.S.M.S. DEGREE EXAMINATION

(Regulations for the candidates admitted from 2013-2014 to 2016-2017 and 2017-2018 onwards)
PAPER II – NOI NAADAL – PAPER - II (PRINCIPLES OF MODERN PATHOLOGY)
Q.P. Code : 601221

Time: Three Hours Answer ALL questions Maximum : 100 Marks

I. Elaborate on : 2x15 = 30
!gm<Mjv!ujvg;!
!
1. Explain Karyotypic abnormolities of chromosomes.
GOviOliOsil<!GjxhiMgjt!uquiqk<K!wPK//!
!!
2. Definition and Types of Embolism and explain about thrombo embolism and pulmonary
thrombo embolism.
wl<hizqsl<!ujvbXk<K?!nke<!ujgh<hiMgjt!wPkq!k<vil<Ohi!wl<hizqsl<?!
hz<Olieiq!k<vil<Ohi!wl<hizqsl<!uquiqk<K!wPkUl</
!
II . Write notes on: 10x5 = 50 !!
!!!RUf;fp tpil vOJf:

1. Difference between nephrotic and nephritic oedema.

ofh<Ovim<cg<?!ofh<jvm<cg<!wClijl!OuXhMk<Kg/!
!
2. Explain Aplastic Anaemia
Whqti^<cg<!neQlqbi!uquiq/!
!
3. Giant cells – Explain.
o\b<e<m<!osz<!.!ujvbX!
!
4. Contrasting features of necrosis and apoptosis.
ofg<Ovisq^<?!nh<nh<Omisq^<!-v{<jmBl<!OuXhMk<Kg/!
!
5. Pathogenesis of systemic Lupus Erythematosus.
ohk<Okio\eqsq^<!.!sq^<mlqg<!Z~h<h^<!wiqk<kqliOmi^^</!
!
6. Strepto coccol infections.
^<omh<Omi!gig<gz<!Ofib<gt<!ujvbX/!
!
7. Diagnosis and prognosis of Amyloidosis.
njlOzib<Omisq^<!Ofib<!liXhiM?!Ofib<!g{qh<H!wPKg/!
!
8. Difference between AML, CML.
AML – CML!OuXhMk<K/!
P.T.O.
 9. Pathological changes of Vit A deficiency.
Vit. A!Gjxhim<ce<!Ofib<!fqjz!liXhiMgt<!uqtg<G/!
!
10. Explain Transfusion reactions.
-vk<kl<!lix<Xkzqz<!Wx<hMl<!uqjtUgjt!uquiq/!

III. Write short notes on: 10x2= 20

FWfpa tpilvOJf:

1. Wernicke-korsakoff’s Syndrome.
Oui<eqg<!Ogii<sOgi0h<!sq{<Ovil</!
!
2. Cardinal signs of Inflammation.
kihqkk<kqe<!Lg<gqb!GxqG{r<gt</!

3. Wear and Tear pigment.

uqbi<!lx<Xl<!cbi<!hqg<ol{<m<!
!
4. Define Ochronosis.
Yg<OviOei^q^<!we<xiz<!we<e@!
!
5. Normal values of MCV, MCH, MCHC.
MCV, MCH, MCHC -ux<xqe<!-bz<hie!ntU!biK@!!

6. Write few causes for thrombocyto penia.

-vk<kkm<Mgt<!Gjx!fqjxg<gie!YiqV!giv{r<gjt!wPK/!
!
7. Howell-jolly –bodies.
auz<\izq!hic^</!

8. Who are called blue bloaters?

‘HT!h<tim<mi<^’< !we<X!bii<!njpg<gh<hMgqe<xei<@!
!
9. Write diagnosis of tuberculosis.
cB,hi<GOtisq^<!Ofib<!g{qh<H!hx<xq!wPK/!
!
10. Cytokines as immune Modulators.
jsm<Omijge<^<!dmz<ue<jlbqz<!osbz<hiM/
********
 THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[BSMS 0323] MARCH 2023 Sub. Code: 1221

(OCTOBER 2022 EXAM SESSION)

THIRD PROFESSIONAL B.S.M.S. DEGREE EXAMINATION

(Regulations for the candidates admitted from 2013-2014 to 2016-2017 and 2017-2018 onwards)
PAPER II – NOI NADAL – PAPER - II (PRINCIPLES OF MODERN PATHOLOGY)

Q.P. Code: 601221

Time: Three Hours Answer ALL questions Maximum : 100 Marks

I. Elaborate on : (2x15 = 30)

!gm<Mjv!ujvg;!
!
1. Define Cancer. Explain the differences between benign and malignent tumours,
greading, sterging and diagnosis of Cancer.
Oge<sjv! ujvbjx! osb<K! hvUl<! lx<Xl<! hvui! Oge<sjv! OuXhMk<kq?!
gqOvcr<?!^<Om\qe<!lx<Xl<!!Ofib<!g{qh<H!Ljxgjt!uquiq/!
!!
2. Explain Megaloblastic anaemia.
olgOzihqti^<cg<!neQlqbiju!uquiq/
!
II . Write notes on: (10x5 = 50) !!
!!!RUf;fp tpil vOJf:

1. Write the structural abnormalities of Chromosome.

GOviOliOsilqe<!dmx<%X!liXhiMgjt!wPKg/!
!
2. Write about infarction.
-e<hqvig<^e<!hx<xq!uquiq/!
!
3. Write types, fate and complications of Tuberculosis.
cB,hi<GOtisq^<!ujgh<hiM?!LcU?!sqg<gz<gjt!wPK/!
!
4. Pathogenesis of hypoxic cell injury.
jahig<sqg<!osz<!-R<Siqbqz<!Ofib<!dVuig<gl</!
!
5. Explain DHF (Dengu Haemorrhagic Fever).
omr<G!aqlviq\<!gib<s<sz<!hx<xq!uquiq/!
!
6. Write short note on Pathologic diagnosis of cancer.
Hx<X!Ofibqe<!ohk<kzi\qg<gz<!Ofib<!g{qh<jh!hx<xq!sqX!Gxqh<H!ujvg/!
!
7. Write about Thalassemia.
kz^Qlqbi!hx<xq!wPKg/!
!
 8. Explain Sidero blastic Anaemia.
sqmOvihqti^<cg<!neQlqbi!hx<xq!wPKg/ P.T.O.!
9. Describe Granulomotous inflammation.
liXhm<m!kihqkl<!hx<xq!wPKg/!
!
10. Pathogenesis of Amyloidosis.
njlzib<Omisq^<!ohk<Okio\eqsq^</ !

III. Write short notes on: (10x2= 20)

FWfpa tpilvOJf:

1. What is Leukemia?
-vk<k!Hx<X!we<xiz<!we<e@!
!
2. What is miliary T.B?
lqzqbiq!cB,hi<GOtisq^<!we<hK!we<e@!

3. Secondary risk factors predisposing to Thrombus.

k<Ovil<h^<!uv!giv{lie!-v{<mil<!fqjz!iq^<g<!hig<mi<gt<!wju@!
!
4. What is Pathological atrophy?
ohk<kzi\qg<gz<!nm<Ovihq!we<xiz<!we<e@!
!
5. What is steatosis?
^<cbOmisq^<!we<xiz<!we<e@!!

6. What is Lepra Cells?

ozh<vi!osz<^<!we<xiz<!we<e@!
!
7. Define Pavementation.
Ohu<ole<Omse<!ujvbX/!

8. Write about dystrophic calcification.

c^<m<Ovihqg<!giz<sqhqOgse<!sqXGxqh<H/!
!
9. Explain Cancer diet.
Oge<si<!Ofib<g<gie!d{U!Ljxgt</!
!
10. Pap test – Give its clinical application.
Ohh<!om^<m<!fjmLjx!hbe<him<jm!wPK/
********
 THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[BSMS 0923] SEPTEMBER 2023 Sub. Code: 1221

(MAY 2023 EXAM SESSION)

THIRD PROFESSIONAL B.S.M.S. DEGREE EXAMINATION

(Regulations for the candidates admitted from 2013-2014 to 2016-2017 and 2017-2018
onwards)
PAPER II – NOI NADAL – PAPER - II (PRINCIPLES OF MODERN PATHOLOGY)

Q.P. Code: 601221

Time: Three Hours Answer ALL questions Maximum: 100 Marks

I. Elaborate on: (2x15 = 30)

!!gm<Mjv!ujvg;!
!
1. Define apoptosis. Explain the molecular mechanism, morphological changes and enlist the
disorders with abnormal apoptosis.
mg;Nghg;nlhrpi] tiuaiw nra;J> mjd; cUthf;fk;> cUttpay; khWghLfs; kw;Wk;
mrhjhuz mg;Nghg;nlhrpdhy; cz;lhFk; Neha;epiyfis gw;wp vOJf.

2. Define thrombosis. Explain the etiopathogenesis and fate of thrombus.

j;Nuhk;Ngh]pi] tiuaiw nra;J mjd; <l;bNahngj;Njhn[dprp]; kw;Wk; Ma;T$l
gupNrhjidfis gw;wp vOJf/!
!
II . Write notes on: (10x5 = 50) !!
! RUf;fp tpil vOJf:
!
1. Write the characteristics of an anaplastic cell.
mdhgpsh];bf; nry;ypd; jd;ikfis gw;wp vOJf.

2. What are the lab findings of HIV/AIDS?

vr;.I.tp/va;l;]; Nehia fz;lwpa cjTk; Ma;tf khWghLfs; ahit?

3. Explain the role of cytokines in inflammation.

jhgpjj;jpy; irl;Nlhifapd;fspd; gq;fspg;ig tptupj;J vOJf.

4. Write the difference between dry and wet gangrene.

l;iukw;Wk; ntl; fhq;fpuPd; NtWghLfis vOJf.

5. Write about the classification of hemolytic anemia.

`PNkhiybf; mdPkpahtpd; tiffis vOJf.

6. Explain chemical carcinogenesis.

nfkpf;fy; fhu;rpNdhn[dprp]; gw;wp vOJf.

7. Write about the factors influencing wound healing.

Gz; MWjypy; jhf;fj;ij cz;lhf;Fk; fhuzpfs; ahit?

8. Write about the lesions in vitamin-C deficiency.

itl;lkpd;-rp Fiwghl;bdhy; cz;lhFk; khWghLfis vOJf.

P.T.O.
9. Applications of pap smear.
ghg; ];kpaupd; gpuNahfq;fis vOJf.

10. Write about the pathogenesis of fatty liver.

ghl;byptu; Neha; cz;lhFk; tpjj;jpid vOJf/ !

III. Write short notes on: (10x2= 20)

FWfpa tpilvOJf:

1. Pompe’s disease.
ghk;g]
; ; Neha;.

2. Causes of pancytopenia.
ghd;irl;NlhgPdpah cz;lhf fhuzq;fs;.

3. Define metaplasia with examples.

nkl;lhgpNsrpahit vLj;Jf;fhl;Lld; tiuaiw nra;f.

4. Congenital syphilis.
fd;n[dply; rpgpyp];.

5. Heart failure cells.

`hu;l; ngapypau; nry;fs;.

6. Define granuloma.
fpuhDNyhkh‐ tiuaiw nra;f.

7. Howell Jolly bodies.

N`hty; [hyp ghB];.

8. Sjogren’s syndrome.
[hfpud;’]; rpd;Nuhk;.

9. Oncogenic DNA viruses.

Md;Nfhn[dpf; b.vd;.V itu];fs;.

10. Marasmus.
kuh];k];.
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