SAFETY DATA SHEET Version 8.

1
Revision Date 31.08.2023
according to Regulation (EC) No. 1907/2006 Print Date 29.01.2024
GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifiers
Product name : Formaldehyde solution
Product Number : 47608
Brand : Sigma
REACH No. : This product is a mixture. REACH Registration Number see
section 3.

1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company :
1.4 Emergency telephone
Emergency Phone # : +(44)-870-8200418 (CHEMTREC (GB))
+(353)-19014670 (CHEMTREC Ireland)
001-803-017-9114 (CHEMTREC India)

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Flammable liquids (Category 3), H226
Acute toxicity, Oral (Category 3), H301
Acute toxicity, Inhalation (Category 2), H330
Acute toxicity, Dermal (Category 3), H311
Skin corrosion (Sub-category 1B), H314
Serious eye damage (Category 1), H318
Skin sensitization (Category 1), H317
Germ cell mutagenicity (Category 2), H341
Carcinogenicity (Category 1B), H350
Specific target organ toxicity - single exposure (Category 1), Eyes, Central nervous system,
H370
Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
For the full text of the H-Statements mentioned in this Section, see Section 16.

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2.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram

Signal Word Danger

Hazard statement(s)
H226 Flammable liquid and vapor.
H301 + H311 Toxic if swallowed or in contact with skin.
H314 Causes severe skin burns and eye damage.
H317 May cause an allergic skin reaction.
H330 Fatal if inhaled.
H335 May cause respiratory irritation.
H341 Suspected of causing genetic defects.
H350 May cause cancer.
H370 Causes damage to organs (Eyes, Central nervous system).
Precautionary statement(s)
P202 Do not handle until all safety precautions have been read and
understood.
P210 Keep away from heat, hot surfaces, sparks, open flames and
other ignition sources. No smoking.
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated
clothing. Rinse skin with water.
P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable
for breathing. Immediately call a POISON CENTER/ doctor.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue
rinsing.
Supplemental Hazard none
Statements

Reduced Labeling (<= 125 ml)

Pictogram

Signal Word Danger

Hazard statement(s)
H330 Fatal if inhaled.
H317 May cause an allergic skin reaction.
H341 Suspected of causing genetic defects.
H350 May cause cancer.
H370 Causes damage to organs.
H314 Causes severe skin burns and eye damage.
H301 + H311 Toxic if swallowed or in contact with skin.
Precautionary statement(s)
P202 Do not handle until all safety precautions have been read and

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 understood.
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated
clothing. Rinse skin with water.
P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable
for breathing. Immediately call a POISON CENTER/ doctor.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue
rinsing.
Supplemental Hazard none
Statements
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.

Ecological information:
The substance/mixture does not contain components considered to have endocrine
disrupting properties according to REACH Article 57(f) or Commission Delegated regulation
(EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

Toxicological information:
The substance/mixture does not contain components considered to have endocrine
disrupting properties according to REACH Article 57(f) or Commission Delegated regulation
(EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

SECTION 3: Composition/information on ingredients

3.2 Mixtures
Synonyms : Formalin

Formula : CH2O
Molecular weight : 30,03 g/mol
Component Classification Concentration
formaldehyde
CAS-No. 50-00-0 Acute Tox. 3; Acute Tox. >= 30 - < 50
EC-No. 200-001-8 2; Acute Tox. 3; Skin Corr. %
Index-No. 605-001-00-5 1B; Eye Dam. 1; Skin
Registration 01-2119488953-20- Sens. 1; Muta. 2; Carc.
number XXXX 1B; STOT SE 3; H301,
H330, H311, H314, H318,
H317, H341, H350, H335
Concentration limits:
>= 25 %: Skin Corr. 1B,
H314; 5 - < 25 %: Skin
Irrit. 2, H315; 5 - < 25 %:

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 Eye Irrit. 2, H319; >= 5
%: STOT SE 3, H335; >=
0,2 %: Skin Sens. 1,
H317;

Methanol
CAS-No. 67-56-1 Flam. Liq. 2; Acute Tox. 3; >= 10 - < 20
EC-No. 200-659-6 STOT SE 1; H225, H301, %
Index-No. 603-001-00-X H331, H311, H370
Registration 01-2119433307-44- Concentration limits:
number XXXX >= 10 %: STOT SE 1,
H370; 3 - < 10 %: STOT
SE 2, H371;

For the full text of the H-Statements mentioned in this Section, see Section 16.

SECTION 4: First aid measures

4.1 Description of first-aid measures
General advice
First aiders need to protect themselves. Show this material safety data sheet to the doctor
in attendance.
If inhaled
After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately
apply artificial respiration, if necessary also oxygen.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with
water/ shower. Call a physician immediately.
In case of eye contact
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist.
Remove contact lenses.
If swallowed
After swallowing: fresh air. Make victim drink ethanol (e.g. 1 drinking glass of a 40%
alcoholic beverage). Call a doctor immediately (mention methanol ingestion). Only in
exceptional cases, if no medical care is available within one hour, induce vomiting (only in
fully conscious persons) and make victim drink ethanol again (approx. 0.3 ml of a 40%
alcoholic beverage/kg body weight/hour). Do not attempt to neutralise.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available

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SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air at elevated temperatures.
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by
keeping a safe distance or by wearing suitable protective clothing.
5.4 Further information
Remove container from danger zone and cool with water. Prevent fire extinguishing water
from contaminating surface water or the ground water system.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance
contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains. Risk of explosion.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions
(see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb®). Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary
measures against static discharge.
Hygiene measures

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 Immediately change contaminated clothing. Apply preventive skin protection. Wash hands
and face after working with substance.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and
sources of ignition. Keep locked up or in an area accessible only to qualified or authorized
persons.
Storage class
Storage class (TRGS 510): 3: Flammable liquids
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

8.1 Control parameters
Ingredients with workplace control parameters
8.2 Exposure controls
Personal protective equipment

Eye/face protection
Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety
goggles
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact
with this product. Dispose of contaminated gloves after use in accordance with
applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU)
2016/425 and the standard EN 374 derived from it.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,2 mm
Break through time: 60 min
Material tested:Dermatril® P (KCL 743 / Aldrich Z677388, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail
sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which
differ from EN 374, contact the supplier of the EC approved gloves. This
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 recommendation is advisory only and must be evaluated by an industrial hygienist
and safety officer familiar with the specific situation of anticipated use by our
customers. It should not be construed as offering an approval for any specific use
scenario.
Body Protection
Flame retardant antistatic protective clothing.
Respiratory protection
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following
standards: DIN EN 143, DIN 14387 and other accompanying standards relating to
the used respiratory protection system.
Recommended Filter type: Filter type ABEK
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory
protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Control of environmental exposure
Do not let product enter drains. Risk of explosion.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties
a) Physical state liquid, clear
b) Color colorless
c) Odor pungent
d) Melting No data available
point/freezing point
e) Initial boiling point 100 °C
and boiling range
f) Flammability (solid, No data available
gas)
g) Upper/lower Upper explosion limit: 70 %(V)
flammability or Lower explosion limit: 7 %(V)
explosive limits
h) Flash point 56,11 °C - closed cup
i) Autoignition No data available
temperature
j) Decomposition No data available
temperature
k) pH No data available
l) Viscosity Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
m) Water solubility completely solubleat 20 °C soluble

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 n) Partition coefficient: log Pow: 0,35
n-octanol/water
o) Vapor pressure 53 hPa at 39 °C
p) Density 1,09 g/mL at 25 °C1,09 g/mL at 20 °C
Relative density No data available
q) Relative vapor No data available
density
r) Particle No data available
characteristics

s) Explosive properties Not classified as explosive.

t) Oxidizing properties none
9.2 Other safety information
Relative vapor 1,04 - (Air = 1.0)
density

SECTION 10: Stability and reactivity

10.1 Reactivity
Vapor/air-mixtures are explosive at intense warming.
10.2 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Contains the following stabilizer(s):
Methanol (10 %)
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
Heating.
10.5 Incompatible materials
Strong oxidizing agents, Aniline, Phenol, Isocyanates, Acid anhydrides, Strong acids,
Strong bases, Amines, Peroxides, Acid chlorides, Alkali metals, Reducing agents
10.6 Hazardous decomposition products
In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects
Mixture
Acute toxicity
Oral: No data available
Acute toxicity estimate Inhalation - 4 h - 1,22 mg/l - vapor(Calculation method)

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 Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of
respiratory tract
Acute toxicity estimate Dermal - 551,05 mg/kg
(Calculation method)
Skin corrosion/irritation
Remarks: Mixture causes burns.
Serious eye damage/eye irritation
Remarks: Mixture causes serious eye damage.
Risk of blindness!
Respiratory or skin sensitization
May cause sensitization by skin contact.
Mixture may cause an allergic skin reaction.
Germ cell mutagenicity
Evidence of genetic defects.
Carcinogenicity
Possible carcinogen.

Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
Mixture causes damage to organs. - Eyes, Central nervous system
Mixture may cause respiratory irritation.
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
11.2 Additional Information
Endocrine disrupting properties
Product:
Assessment : The substance/mixture does not contain
components considered to have endocrine
disrupting properties according to REACH Article
57(f) or Commission Delegated regulation (EU)
2017/2100 or Commission Regulation (EU)
2018/605 at levels of 0.1% or higher.
burning sensation, Cough, wheezing, laryngitis, Shortness of breath, spasm, inflammation
and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis,
pulmonary edema, Material is extremely destructive to tissue of the mucous membranes
and upper respiratory tract, eyes, and skin., To the best of our knowledge, the chemical,
physical, and toxicological properties have not been thoroughly investigated.
Other dangerous properties can not be excluded.

This substance should be handled with particular care.

Handle in accordance with good industrial hygiene and safety practice.

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 Components
formaldehyde
Acute toxicity
LD50 Oral - Rat - 100 mg/kg
Remarks: (Lit.)
Acute toxicity estimate Oral - 100 mg/kg
(ATE value derived from LD50/LC50 value)
LC50 Inhalation - Rat - male and female - 4 h - < 0,57 mg/l - vapor
(OECD Test Guideline 403)
LD50 Dermal - Rabbit - 270 mg/kg
Remarks: (RTECS)
Acute toxicity estimate Dermal - 270 mg/kg
(ATE value derived from LD50/LC50 value)
Skin corrosion/irritation
Skin - Rabbit
Result: Causes burns. - 20 h
(OECD Test Guideline 404)
Serious eye damage/eye irritation
Remarks: Causes serious eye damage.
Respiratory or skin sensitization
Local lymph node assay (LLNA) - Mouse
Result: positive
(OECD Test Guideline 429)
Germ cell mutagenicity
Suspected of causing genetic defects.
Carcinogenicity
Presumed to have carcinogenic potential for humans
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
May cause respiratory irritation.
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available

Methanol
Acute toxicity
Acute toxicity estimate Oral - 100,1 mg/kg
(Expert judgment)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table
3.1/3.2)
Symptoms: Nausea, Vomiting
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 Acute toxicity estimate Inhalation - 4 h - 3,1 mg/l - vapor
(Expert judgment)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table
3.1/3.2)
Symptoms: Irritation symptoms in the respiratory tract.
Acute toxicity estimate Dermal - 300,1 mg/kg
(Expert judgment)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table
3.1/3.2)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation
Remarks: (ECHA)
Remarks: Drying-out effect resulting in rough and chapped skin.
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation
Remarks: (ECHA)
Respiratory or skin sensitization
Sensitisation test: - Guinea pig
Result: negative
(OECD Test Guideline 406)
Germ cell mutagenicity
Based on available data the classification criteria are not met.
Test Type: Ames test
Test system: Salmonella typhimurium
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster lung cells
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male and female - Bone marrow
Result: negative
Carcinogenicity
Did not show carcinogenic effects in animal experiments.
Reproductive toxicity
Based on available data the classification criteria are not met.
Specific target organ toxicity - single exposure
Causes damage to organs. - Eyes, Central nervous system
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table
3.1/3.2)
Acute oral toxicity - Nausea, Vomiting
Acute inhalation toxicity - Irritation symptoms in the respiratory tract.
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available

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SECTION 12: Ecological information
12.1 Toxicity
Mixture
No data available
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.
12.6 Endocrine disrupting properties
Product:
Assessment : The substance/mixture does not contain components
considered to have endocrine disrupting properties
according to REACH Article 57(f) or Commission
Delegated regulation (EU) 2017/2100 or Commission
Regulation (EU) 2018/605 at levels of 0.1% or higher.

12.7 Other adverse effects

No data available
Components
formaldehyde
Toxicity to fish static test LC50 - Morone saxatilis - 6,7 mg/l - 96 h
Remarks: (ECHA)

Toxicity to daphnia static test EC50 - Daphnia pulex (Water flea) - 5,8 mg/l - 48 h
and other aquatic (OECD Test Guideline 202)
invertebrates

Toxicity to algae static test EC50 - Desmodesmus subspicatus (green algae) -

4,89 mg/l - 72 h
(OECD Test Guideline 201)
Toxicity to bacteria static test EC50 - activated sludge - 19 mg/l - 3 h
(OECD Test Guideline 209)
Toxicity to daphnia semi-static test NOEC - Daphnia magna (Water flea) - >= 6,4
and other aquatic mg/l - 21 d
invertebrates(Chronic (OECD Test Guideline 211)
toxicity)

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 Methanol
Toxicity to fish flow-through test LC50 - Lepomis macrochirus (Bluegill) -
15.400,0 mg/l - 96 h
(US-EPA)
Toxicity to daphnia semi-static test EC50 - Daphnia magna (Water flea) - 18.260
and other aquatic mg/l - 96 h
invertebrates (OECD Test Guideline 202)

Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata (green

algae) - ca. 22.000,0 mg/l - 96 h
(OECD Test Guideline 201)
Toxicity to bacteria static test IC50 - activated sludge - > 1.000 mg/l - 3 h
(OECD Test Guideline 209)
Toxicity to NOEC - Oryzias latipes (Orange-red killifish) - 7.900 mg/l - 200
fish(Chronic toxicity) h
Remarks: (External MSDS)

SECTION 13: Disposal considerations

13.1 Waste treatment methods
No data available

SECTION 14: Transport information

14.1 UN number
ADR/RID: 1198 IMDG: 1198 IATA: 1198
14.2 UN proper shipping name
ADR/RID: FORMALDEHYDE SOLUTION, FLAMMABLE
IMDG: FORMALDEHYDE SOLUTION, FLAMMABLE
IATA: Formaldehyde solution, flammable
14.3 Transport hazard class(es)
ADR/RID: 3 (8) IMDG: 3 (8) IATA: 3 (8)
14.4 Packaging group
ADR/RID: III IMDG: III IATA: III
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
Further information : No data available

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SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
Authorisations and/or restrictions on use
REACH - Restrictions on the manufacture, : Methanol
placing on the market and use of certain
dangerous substances, mixtures and articles
(Annex XVII)

National legislation
Seveso III: Directive 2012/18/EU of the H2 ACUTE TOXIC
European Parliament and of the Council
on the control of major-accident hazards
involving dangerous substances.
P5c FLAMMABLE LIQUIDS

H2 ACUTE TOXIC

P5c FLAMMABLE LIQUIDS

22 Methanol

Other regulations
Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or
stricter national regulations where applicable.
Take note of Dir 94/33/EC on the protection of young people at work.
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out

SECTION 16: Other information

Full text of H-Statements referred to under sections 2 and 3.
H225 Highly flammable liquid and vapor.
H226 Flammable liquid and vapor.
H301
H301 + H311 Toxic if swallowed.
H311 Toxic if swallowed or in contact with skin.
H314 Toxic in contact with skin.
H315 Causes severe skin burns and eye damage.
H317 Causes skin irritation.
H318 Toxic if swallowed or in contact with skin.
H319 Causes severe skin burns and eye damage.
H330 May cause an allergic skin reaction.
H331 Fatal if inhaled.
H335 May cause respiratory irritation.

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 H341 Suspected of causing genetic defects.
H350 May cause cancer.
H370 May cause an allergic skin reaction.
H371 Causes serious eye damage.
Full text of other abbreviations
ADN - European Agreement concerning the International Carriage of Dangerous Goods
by Inland Waterways; ADR - Agreement concerning the International Carriage of
Dangerous Goods by Road; AIIC - Australian Inventory of Industrial Chemicals; ASTM -
American Society for the Testing of Materials; bw - Body weight; CMR - Carcinogen,
Mutagen or Reproductive Toxicant; DIN - Standard of the German Institute for
Standardisation; DSL - Domestic Substances List (Canada); ECx - Concentration
associated with x% response; ELx - Loading rate associated with x% response; EmS -
Emergency Schedule; ENCS - Existing and New Chemical Substances (Japan); ErCx -
Concentration associated with x% growth rate response; GHS - Globally Harmonized
System; GLP - Good Laboratory Practice; IARC - International Agency for Research on
Cancer; IATA - International Air Transport Association; IBC - International Code for the
Construction and Equipment of Ships carrying Dangerous Chemicals in Bulk; IC50 - Half
maximal inhibitory concentration; ICAO - International Civil Aviation Organization;
IECSC - Inventory of Existing Chemical Substances in China; IMDG - International
Maritime Dangerous Goods; IMO - International Maritime Organization; ISHL - Industrial
Safety and Health Law (Japan); ISO - International Organisation for Standardization;
KECI - Korea Existing Chemicals Inventory; LC50 - Lethal Concentration to 50 % of a
test population; LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose);
MARPOL - International Convention for the Prevention of Pollution from Ships; n.o.s. -
Not Otherwise Specified; NO(A)EC - No Observed (Adverse) Effect Concentration;
NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable Effect Loading
Rate; NZIoC - New Zealand Inventory of Chemicals; OECD - Organization for Economic
Co-operation and Development; OPPTS - Office of Chemical Safety and Pollution
Prevention; PBT - Persistent, Bioaccumulative and Toxic substance; PICCS - Philippines
Inventory of Chemicals and Chemical Substances; (Q)SAR - (Quantitative) Structure
Activity Relationship; REACH - Regulation (EC) No 1907/2006 of the European
Parliament and of the Council concerning the Registration, Evaluation, Authorisation and
Restriction of Chemicals; RID - Regulations concerning the International Carriage of
Dangerous Goods by Rail; SADT - Self-Accelerating Decomposition Temperature; SDS -
Safety Data Sheet; TCSI - Taiwan Chemical Substance Inventory; TECI - Thailand
Existing Chemicals Inventory; TSCA - Toxic Substances Control Act (United States); UN
- United Nations; UNRTDG - United Nations Recommendations on the Transport of
Dangerous Goods; vPvB - Very Persistent and Very Bioaccumulative
Classification of the mixture Classification procedure:
Flam. Liq.3 H226 Based on product data or
assessment
Acute Tox.3 H301 Calculation method
Acute Tox.2 H330 Calculation method
Acute Tox.3 H311 Calculation method
Skin Corr.1B H314 Calculation method
Eye Dam.1 H318 Calculation method
Skin Sens.1 H317 Based on product data or

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 assessment
Muta.2 H341 Calculation method
Carc.1B H350 Calculation method
STOT SE1 H370 Calculation method
STOT SE3 H335 Calculation method

Further information
The above information is believed to be correct but does not purport to be all inclusive
and shall be used only as a guide. The information in this document is based on the
present state of our knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any guarantee of the properties of
the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any
damage resulting from handling or from contact with the above product. See
www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional
terms and conditions of sale.

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match the product purchased as we transition our branding. However, all of the
information in the document regarding the product remains unchanged and matches the
product ordered. For further information please contact mlsbranding@sial.com.

Sigma- 47608 Page 16 of 16

The life science business of Merck operates as MilliporeSigma in the US and

Canada