1. In Gabriel synthesis, amine is always: (1) aliphatic primary amine (3) (2) aliphatic secondary amine (3) aromatic primary amine (4) aromatic secondary amine (4)
2. In the Hofmann-Bromamide rearrangement
intermediate compounds are: R – C– NHBr || (1) O 5. O || R — C— N — Br Na + (2) (3) R — N == C == O The end product B of the above reaction is: (4) All of these (1)
3. In the given reaction CH3–CH2–NH–CH2–CH2–Cl (2)
(i)CH I(excess) ⎯⎯⎯⎯⎯⎯3 (ii)AgOH/ →[X] is the major product; [X] will be: (3) (1) CH2 = CH2 (2) CH2 = CHCl (3) 1 : 1 ratio of (1) and (2) (4) (4) CH3 – CH2 – Cl
4. The major product formed in the reaction: 6. For the following compounds, which is the strongest base and which is strongest acid?
p−TsOH(Trace) ⎯⎯⎯⎯⎯⎯ C H , → 6 6
(1) (1) II = Strongest base, I = Strongest acid (2) IV = Strongest base, III = Strongest acid (2) (3) III = Strongest base, IV = Strongest acid (4) II = Strongest base, III = Strongest acid
1 7. Repeated Hofmann elimination reaction (exhaustive 11. How many amide isomer exist for C4H9ON that methylation followed by heating with AgOH) will do not form amine on treatment with Br2-NaOH? often remove a nitrogen atom from an amine 12. How many amide isomers exist for C5H11ON that molecule. Which of the following compounds is the on treatment with NaOH/Br2 give amines? likely product in this case? 13. How many total amide isomers exist for C3H7ON?
(1) (2) 14. How many tertiary amines are possible for C6H15N?
15. How many different isomers of amine exist for
(3) (4) C5H13N that on treatment with tosyl chloride to form precipitate which does not dissolve in KOH solution?
8. Which of the following compounds loses optical
16. How many different isomers of C4H11N on activity due to pyramidal inversion? heating with CS2 followed by the addition of HgCl2 gives alkyl isothiocyanide(RNCS)? (1) (2) 17. An organic acid X has molecular formula C8H16O2 X on heating with NH3 forms Y. Y on treatment with alkaline Br2 solution forms Z. Z on treatment with nitrous acid followed by heating with (3) (4) concentrated H2SO4 solution gives 2, 4-dimethyl- 2-pentene. How many different acids X can 9. Which of the following compounds is an amine? satisfy the above-mentioned condition?
(1) (2) 18. How many different isomers exist for C4H11N?
19. Of the following reactions, how many reaction,
are used for the preparation of amines? (3) (4)
10. Cyclohexanol can be converted into
cyclohexylamine by following two routes. Which of the following methods is expected to give good yield of cyclohexylamine? (1) 20. Of the following amines how many can be separated by Hofmann’s mustard oil reaction?
(2)
(3) Both are equally suitable
(4) Neither of the two
2 21. Find out number of reactions which involve 23. How many 1° amine of the formula C5H13N can electron deficient nitrogen during reaction be used to resolve racemic 2-methylbutanoic acid? mechanism.
24. (a)
X = moels of KOH consumed is :
(b)
25. Number of moles of N2 liberated by reaction of
(c)
(d)
(e) With NaNO2/HCl/0° in excess are : (f)
(g)
(h)
22. Examine the structural formulas of following
compounds and identify how many compounds are more basic than aniline.
