Gigantism
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Recent papers in Gigantism
In 1886 Pierre Marie used the term "acromegaly" for the first time and gave a full description of the characteristic clinical picture. However several others had already given clear clinical descriptions before him and sometimes... more
Exceptionally preserved fossils from the Palaeozoic era provide crucial insights into arthropod evolution, with recent discoveries bringing phylogeny and character homology into sharp focus. Integral to such studies are anomalocaridids, a... more
Sauropod (or, more correctly, eusauropod) dinosaurs are highly distinctive, not only in their overall body form, but also in respect to many details of their anatomy. In comparison with basal dinosaurs, typical sauropods are characterized... more
Recent evidence for feathers in theropods has led to speculations that the largest tyrannosaurids, including Tyrannosaurus rex, were extensively feathered. We describe fossil integument from Tyrannosaurus and other tyrannosaurids... more
Ein Flügelfragment aus Seeablagerungen der Meisen heim-Formation des Unteren Rotliegend (Autunium) bei Obermoschel ist der erste Nachweis von Riesen-Urlibellen für das Permokarbon des Saar-Nahe-Beckens. Mit einer Flügelspannweite von... more
The herbivorous sauropod dinosaurs of the Jurassic and Cretaceous periods were the largest terrestrial animals ever, surpassing the largest herbivorous mammals by an order of magnitude in body mass. Several evolutionary lineages among... more
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En el mundo ficcional rabelaisiano, universo dominado por la abundancia, las dimensiones y cantidades colosales, el cuerpo humano no puede menos que alcanzar su afirmación hiperbólica más completa: el gigantismo. El objetivo de este... more
Endocrine disorders during growth and development that occur due to the secretion of excessive growth hormones are very rare in archaeological and modern populations. The human skeletal remains analyzed in this paper belong to an... more
This report suggests the association of congenital diaphragmatic hernia in Simpson-Golabi-Behmel syndrome by describing two unrelated males with this malformation. One male was the maternal half-nephew of our previously reported... more
El propósito del artículo es revisar la historia vital y sobre todo la historia post mórtem del “gigante” español con mayor proyección mediática de todos los tiempos: Agustín Luengo Capilla (1849-1875), conocido como “El Gigante... more
We reported on thirteen children affected with malformative syndromes associated with mental retardation. MRI examination showed in all of them different types of anomalies; agenesis of corpus callosum, ventricular dilatation and cerebral... more
The skeletons of 2 famous acromegalic giants: Charles Byrne (1761-1783) and Henri Cot = Joseph Dusorc (1883-1912) and the embalmed body of the famous acromegalic giant Édouard Beaupré (1881-1904) all ended up in the medical collections of... more
Familial acromegaly/gigantism occurring in the absence of multi- ple endocrine neoplasia type I (MEN-1) or the Carney complex has been reported in 18 families since the biochemical diagnosis of GH excess became available, and the genetic... more
X-linked acro-gigantism (X-LAG) is a new syndrome of pituitary gigantism, caused by microduplications on chromosome Xq26.3, encompassing the gene GPR101, which is highly upregulated in pituitary tumors. We conducted this study to explore... more
The aryl hydrocarbon receptor interacting protein (AIP) founder mutation R304* (or p.R304*; NM_003977.3:c.910C>T, p.Arg304Ter) identified in Northern Ireland (NI) predisposes to acromegaly/gigantism; its population health impact... more
Entre les années 1970 et 1980, les écologistes ont identifié les principes théoriques qui auraient pu guider la gestion des villes et des territoires, et être mis en pratique dans des expériences micro-territoriales, germes d'autres... more
Background: Thermal limits may arise through a mismatch between oxygen supply and demand in a range of animal taxa. Whilst this oxygen limitation hypothesis is supported by data from a range of marine fish and invertebrates, its... more
Based on the fossil record, we explore the macroevolutionary relationship between species richness and gigantism in cowries (Cypraeidae), the best-studied family of gastropods, with a global diversity distribution that parallels that of... more
Giant gastropods are among the largest mollusks in the fossil record, but their potential as paleoseasonality archives has received little attention. Here, we combine stable isotope and trace element analyses with microscopic observations... more
[first published in "Open monument : research into ephemeral, commemorative architecture and modernist patrimony ; [on the occasion of the Exhibition Open Monument at Kunstraum Kreuzberg, Bethanien Berlin, 4th May to 16th June 2013] / ed.... more
X-linked acrogigantism (X-LAG) syndrome is a newly-described form of inheritable pituitary gigantism that begins in early childhood and is usually associated with markedly elevated growth hormone (GH) and prolactin secretion by mixed... more
Terza e ultima parte della critica del gigantismo e delle sue ripercussioni nell'assetto territoriale e nel governo delle città.