IRF2

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Interferon regulatory factor 2 is a protein that in humans is encoded by the IRF2 gene.[1]

Function

IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.[2]

See also

Interactions

IRF2 has been shown to interact with BRD7,[3] EP300[4] and PCAF.[4][5]

References

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Further reading

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External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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