IRF2
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Interferon regulatory factor 2 is a protein that in humans is encoded by the IRF2 gene.[1]
Function
IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.[2]
See also
Interactions
IRF2 has been shown to interact with BRD7,[3] EP300[4] and PCAF.[4][5]
References
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Further reading
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External links
- IRF2 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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