NEUROD1
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Neurogenic differentiation 1 (NeuroD1), also called β2,[1] is a transcription factor of the NeuroD-type. It is encoded by the human gene NEUROD1.
It is a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.[2]
Interactions
NEUROD1 has been shown to interact with MAP3K10,[3] MAFA[4] and Cyclin D1.[5]
References
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Further reading
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External links
- NEUROD1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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