SIX4

SIX homeobox 4
SIX homeobox 4
Identifiers
Symbols	SIX4 ; AREC3
External IDs	OMIM: 606342 MGI: 106034 HomoloGene: 69089 GeneCards: SIX4 Gene
Gene ontology
Molecular function	• RNA polymerase II core promoter proximal region sequence-specific DNA binding; • transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding;
Cellular component	• nucleus; • cytoplasm;
Biological process	• transcription from RNA polymerase II promoter; • skeletal muscle tissue development; • regulation of synaptic growth at neuromuscular junction; • male gonad development; • anatomical structure morphogenesis; • male sex determination; • olfactory placode formation; • regulation of protein localization; • protein localization to nucleus; • inner ear morphogenesis; • negative regulation of apoptotic process; • negative regulation of neuron apoptotic process; • tongue development; • sarcomere organization; • negative regulation of transcription, DNA-templated; • positive regulation of transcription, DNA-templated; • positive regulation of transcription from RNA polymerase II promoter; • male sex differentiation; • thymus development; • generation of neurons; • embryonic cranial skeleton morphogenesis; • regulation of epithelial cell proliferation; • myoblast migration; • pharyngeal system development; • myotome development; • fungiform papilla morphogenesis; • trigeminal ganglion development; • metanephric mesenchyme development; • regulation of branch elongation involved in ureteric bud branching; • positive regulation of ureteric bud formation; • positive regulation of branching involved in ureteric bud morphogenesis; • skeletal muscle fiber differentiation; • negative regulation of satellite cell differentiation;
	Sources: Amigo / QuickGO
Orthologs
Species	Human
Entrez	51804
Ensembl	ENSG00000100625
UniProt	Q9UIU6
RefSeq (mRNA)	NM_017420
RefSeq (protein)	NP_059116
Location (UCSC)	Chr 14:; 60.71 – 60.72 Mb
PubMed search	[1]
	v; t; e;

Homeobox protein SIX4 is a protein that in humans is encoded by the SIX4 gene.^[1]^[2]^[3]

References

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This article on a gene on human chromosome 14 is a stub. You can help Wikipedia by expanding it.

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[1]

[2]

[3]

SIX4

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