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    Rammbo Worksheet Prognosis Jawaban Sesuai Worksheet

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    Disa Edralyn
    The document describes a randomized controlled trial that evaluated the effects of balanced crystalloids versus colloids for fluid management in major abdominal surgery patients. It summarizes: - 160 patients were randomly assigned in a blinded manner to receive either balanced crystalloids or colloid solutions for intraoperative fluid boluses. - Patients and investigators were blinded to treatment group assignment. Outcome measurements were performed objectively by investigators blinded to treatment. - Both treatment groups received similar premedication, anesthesia induction, and intraoperative maintenance, limiting potential confounding factors between groups.

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    Rammbo Worksheet Prognosis Jawaban Sesuai Worksheet

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    Disa Edralyn
    32 views3 pages
    The document describes a randomized controlled trial that evaluated the effects of balanced crystalloids versus colloids for fluid management in major abdominal surgery patients. It summarizes: - 160 patients were randomly assigned in a blinded manner to receive either balanced crystalloids or colloid solutions for intraoperative fluid boluses. - Patients and investigators were blinded to treatment group assignment. Outcome measurements were performed objectively by investigators blinded to treatment. - Both treatment groups received similar premedication, anesthesia induction, and intraoperative maintenance, limiting potential confounding factors between groups.

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    The document describes a randomized controlled trial that evaluated the effects of balanced crystalloids versus colloids for fluid management in major abdominal surgery patients. It summarizes: - 160 patients were randomly assigned in a blinded manner to receive either balanced crystalloids or colloid solutions for intraoperative fluid boluses. - Patients and investigators were blinded to treatment group assignment. Outcome measurements were performed objectively by investigators blinded to treatment. - Both treatment groups received similar premedication, anesthesia induction, and intraoperative maintenance, limiting potential confounding factors between groups.

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    32 views3 pages

    Rammbo Worksheet Prognosis Jawaban Sesuai Worksheet

    Uploaded by

    Disa Edralyn
    The document describes a randomized controlled trial that evaluated the effects of balanced crystalloids versus colloids for fluid management in major abdominal surgery patients. It summarizes: - 160 patients were randomly assigned in a blinded manner to receive either balanced crystalloids or colloid solutions for intraoperative fluid boluses. - Patients and investigators were blinded to treatment group assignment. Outcome measurements were performed objectively by investigators blinded to treatment. - Both treatment groups received similar premedication, anesthesia induction, and intraoperative maintenance, limiting potential confounding factors between groups.

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    VALIDITAS INTERNAL

    RAMMBO Worksheet Prognosis Jawaban Sesuai Worksheet


    1. Recruitment Apakah subjek mewakili, dilakukan YA ;
    randomisasi dan terdapat kemiripan One hundred and sixty patients were
    antara kedua grup subjek ? enrolled in the protocol. All patients had
    maintenance-balanced crystalloid
    administration of 3 ml · kg–1 · h–1. A
    closed-loop system delivered additional
    100-ml fluid boluses (patients were
    randomized to receive either a
    balanced-crystalloid or colloid solution)
    according to a predefined goal-directed
    strategy, using a stroke volume and
    stroke volume variation monitor. All
    patients were included in the analysis.
    2. Allocation Apakah penempatan I dan C diacak dan YA ; The morning of surgery, blinded
    disembunyikan? fluid solutions (visually identical plastic
    Kelompok I dan C sebanding sebanding bags of 500ml) were delivered to the
    pada awal percobaan? anesthesiologist in charge of the patient.
    VALIDITAS INTERNAL
    RAMMBO Worksheet Prognosis Jawaban Sesuai Worksheet
    3. Maintenance Apakah kelompok memperoleh YA ; . In both groups, premedication
    kointervensi yang sama? consisted of 0.5 mg of alprazolam, given
    the morning of the surgery. Some
    patients had an epidural catheter placed
    prior to anesthesia induction in the
    operating room; however, most patients
    received only a spinal morphine
    injection.
    Anesthesia was induced with lean body
    weight–adjusted doses of propofol (2
    mg/kg), remifentanil (Minto
    Pharmacokinetics model: 2 to 6 ng/ ml),
    and rocuronium (0.5 mg/kg), and was
    maintained with remifentanil (2 to 6
    ng/ml) and volatile anesthetic (either
    sevoflurane or desflurane, depending on
    physician prefer- ences). After
    intubation, a protective ventilation
    approach was applied, consisting of a
    tidal volume of 8 ml/kg of lean body
    weight, a positive end expiratory
    pressure of 5 to 7 cm H2O, and
    recruitment maneuvers whenever
    necessary. The respiratory rate was set
    to achieve an end-tidal carbon diox- ide
    VALIDITAS INTERNAL
    RAMMBO Worksheet Prognosis Jawaban Sesuai Worksheet
    4. Measurement Apakah subjek dan penilai disamarkan YA ; Study fluids were only identified by
    Binding terhadap perlakuan ? the assigned patient number. The
    Outcome Apakah pengukurannya objektif preparation, storage, and dispensing of
    the study fluids was done independently
    by the hospital pharmacy of each insti-
    tution. Importantly, all investigators
    remained blinded to the treatment
    allocation until the end of the study and
    the finalization of the statistical analysis.
    Intraoperative data were collected by
    the investigators and postoperative data
    by nurses, residents in anesthesiology,
    and research medical students not
    involved in the trial. The Post-Operative
    Morbidity Survey (POMS) score was
    determined on the morning of
    postoperative day 2 (POD2) by two
    investigators who remained blinded to
    the group allocation at that time (A.J.
    and A.D.).

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