Eksaprolol
Изглед
Nazivi | |
---|---|
IUPAC naziv
1-(2-Cikloheksilfenoksi)-3-(propan-2-ilamino)propan-2-ol
| |
Drugi nazivi
Esprolol
| |
Identifikacija | |
3D model (Jmol)
|
|
ChemSpider | |
KEGG[1] | |
UNII | |
| |
Svojstva | |
C18H29NO2 | |
Molarna masa | 291,44 g·mol−1 |
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa). | |
Reference infokutije | |
Exaprolol je antagonist bet-adrenoreceptora.[4]
Sinteza
[уреди | уреди извор]Reference
[уреди | уреди извор]- ^ Joanne Wixon; Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast. 17 (1): 48—55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
- ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.
- ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.
- ^ Van Waarde, A; Doorduin, J; De Jong, JR; Dierckx, RA; Elsinga, PH (2008). „Synthesis and preliminary evaluation of (S)-11C-exaprolol, a novel beta-adrenoceptor ligand for PET”. Neurochemistry International. 52 (4–5): 729—33. PMID 17961850. doi:10.1016/j.neuint.2007.09.009.
- ^ Carissimi, M; Gentili, P; Grumelli, E; Milla, E; Picciola, G; Ravenna, F (1976). „Basic ethers of cyclohexylphenols with beta-blocking activity: Synthesis and pharmacological study of exaprolol”. Arzneimittel-Forschung. 26 (4): 506—16. PMID 8056.