Homeobox A10
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Homeobox protein Hox-A10 is a protein that in humans is encoded by the HOXA10 gene.[1][2][3]
Function
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants encoding different isoforms have been described.[3]
Interactions
Homeobox A10 has been shown to interact with PTPN6.[4]
See also
References
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External links
- HOXA10 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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