NFE2L3
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Nuclear factor erythroid 2-related factor 3, also known as NF-E2-related factor 3 or Nrf3, is a transcription factor that in humans is encoded by the NFE2L3 gene.[1][2]
Function
This gene encodes a member of the cap 'n' collar basic-region leucine zipper (bZIP) family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors (MAF) to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope.[1]
References
Further reading
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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